Niclosamide Drug

Niclosamide Bolus is anthelmintic containing Niclosamide B.P. Vet, active against tapeworms and intestinal flukes such as paramphistomum in ruminants. Niclosamide Bolus inhibits phosphorylation in the mitochondria of cestodes. Both in vitro and in vivo, the scolex and proximal segments are killed on contact with the drug. The loosened scolex may be digested in the intestine; hence, it may be impossible to identify the scolex in the faeces. Niclosamide Bolus is taenicidal in action and eliminates not only the segments but also scolex.