Plastic Norditropin Pen

Beginning of adult growth hormone deficiency : In adults, insulin tolerance testing is the most common diagnostic test.  However, compared to the insulin tolerance test, these tests are less convincing for diagnosis.
Dose :

• Dose of 0.025-0.035 mg / kg of body weight per day or 0.7-1.0 mg / m² of body surface area per day
• Prader-Willi Syndrome
• Dose of 0.025-0.035 mg / kg of body weight per day or 0.7-1.0 mg / m² of body surface area per day.
• The recommended dose is usually 0.035 mg / kg body weight per day until reaching the final size.

Subcutaneous injection is the recommended route of administration. Some studies have shown that a replacement of the im injection with sc injection leads to an acceleration of growth in one year. Moreover, an im injection causes a high, supraphysiological, but brief serum growth hormone level. The sc injection makes it possible to achieve more regular serum concentrations, better suited to the physiological values. During injection sc, the injection site must be changed between each injection, in order to avoid the appearance of lipoatrophy.
Duration of treatment: The duration of the treatment usually carried out continuously for several years depends on the evolution of the body size and the intended therapeutic objective
Warnings and Precaution :

• The maximum recommended daily dose (see “ Dosage / Directions for Use”) should not be exceeded.
• Long-term effect
• There are no long-term data for Norditropin in both Turner’s syndrome and chronic renal failure, and treatment should be under strict medical supervision.

Side effects : Especially in adults, fluid retention accompanied by peripheral edema may occur. Carpal tunnel syndrome is rare, but may occur in adults. Symptoms are usually transient, dose-dependent, and may require a dose reduction.