Ketotifen fumarate is a cycloheptathiophene blocker of histamine h1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
Ketotifen fumarate is the fumarate salt of ketotifen, a cycloheptathio- phene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (h1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.

Ketotifen fumarate is a cycloheptathiophene blocker of histamine h1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
Ketotifen fumarate is the fumarate salt of ketotifen, a cycloheptathio- phene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (h1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.