Pantoprazole, Brand Name : Pantoansh-DSR, Form : Powder

Niksan Pharmaceutical is leading manufacturer and distributer of thePantoprazole among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Pantoprazole API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Pantoprazole in the domestic level as well as the international market. 

Niksan Pharmaceutical provides Pantoprazole API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Pantoprazole API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Pantoprazole is a type of medicine called a proton pump inhibitor (PPI). Proton pumps are enzymes in the lining of your stomach that help it make acid to digest your food. Pantoprazole prevents proton pumps from working properly. This reduces the amount of acid the stomach makes.

SYNONYMS: Pantoprazol, Pantoprazole, Pantoprazolum

IUPAC NAME:6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole

CAS NO: 102625-70-7

FORMULA: C₁₆H₁₅F₂N₃O₄S

MOLECULAR MASS:383.37

STORAGE OF PANTOPRAZOLE:Store PROTONIX I.V. for Injection vials at 20° - 25°C (68° - 77°F); excursions permitted to 15° - 30°C (59° - 86°F). [See USP Controlled Room Temperature.] Protect from light.

APPLICATIONS OF PANTOPRAZOLE:Pantoprazole reduces the amount of acid your stomach makes. It's used for heartburn, acid reflux and gastro-oesophageal reflux disease (GORD) – GORD is when you keep getting acid reflux. It's also taken to prevent and treat stomach ulcers.

HOW TO USE: For the treatment of conditions where the stomach produces too much acid, pantoprazole is usually taken twice a day. The delayed-release tablets are usually taken with or without food, and the granules are usually taken 30 minutes before a meal. Take pantoprazole at around the same time(s) every day.

HOW PANTOPRAZOLE WORKS: Proton pumps are enzymes in the lining of your stomach that help it make acid to digest your food. Pantoprazole prevents proton pumps from working properly. This reduces the amount of acid the stomach makes.

CONTRAINDICATIONS OF PANTOPRAZOLE: Pantoprazole is contraindicated in patients with a history of hypersensitivity to the drug itself, components of the formulation, and/or other benzimidazole PPIs, including omeprazole, lansoprazole, rabeprazole, esomeprazole, or dexlansoprazole.

PHARMACOKINETICS OF PANTOPRAZOLE:Pantoprazole is extensively metabolized in the liver through the cytochrome P-450 system, predominantly by CYP2C19 demethylation with subsequent sulfation and has a serum elimination half-life of about 1.1 hours. Pantoprazole does not accumulate, and its pharmacokinetics are not altered by multiple daily dosing.

SIDE EFFECTS OF PANTOPRAZOLE:  Check with your doctor immediately if you or your child has stomach cramps, bloated feeling, watery and severe diarrhea which may also be bloody sometimes, fever, nausea or vomiting, or unusual tiredness or weakness. Pantoprazole may increase your risk of having fractures of the hip, wrist, and spine.