Paracetamol

Paracetamol, 4-acetamidophenol, acetaminophen
synonyms: 4-acetamidophenol;4-acetaminophenol;4'-hydroxyacetanilide;4-hydroxyacetanilide;4-(acetylamino)phenol;acetaminophen;acetyl-p-aminophenol;akos bbs-00008094
cas: 103-90-2
mf: c8h9no2
mw: 151.16
einecs: 203-157-5
chemical properties white solid
usage antiinfectant
usage dispersing agent in liquid scintillation counting
usage analgesic; antipyretic
general description odorless white crystalline solid. Bitter taste. Ph (saturated aqueous solution) about 6.
Air & water reactions slightly soluble in water.
Reactivity profile 4-acetamidophenol is sensitive to light. Incompatible with strong oxidizers. .
Fire hazard flash point data for 4-acetamidophenol are not available; however, 4-acetamidophenol is probably combustible.
Biological activity cyclooxygenase inhibitor; may be selective for cox-3 (ic 50 values are 460, > 1000 and > 1000 μ m for canine cox-3, and murine cox-1 and cox-2 respectively). Widely used analgesic and antipyretic agent.
Paracetamol, 4-acetamidophenol, acetaminophen usage:
1. Antipyretic analgesics, international non proprietary drug called paracetamol. It is the most commonly used non anti-inflammatory antipyretic analgesic, antipyretic effect similar to aspirin, the analgesic effect is weak, no anti rheumatic effects of anti inflammation, is the best varieties of acetanilide drugs. Particularly suitable for carboxylic acid can not be used drugs patients. For the common cold, toothache embolism. Acetaminophen is intermediate in organic synthesis, hydrogen peroxide stabilizer, photographic chemicals.
2. Used as antipyretic, analgesic, anti rheumatic drugs.