Deferasirox Dispersible Tablets 125 Mg (Defrataj 125 Mg)

DefraTaj (deferasirox) binds to iron and removes it from the blood stream. DefraTajis used to treat iron overload caused by blood transfusions in adults and children at least 2 years old. DefraTaj is a tridentate ligand that binds iron with high affinity, forming a 2:1 complex that is excreted in bile and eliminated primarily via the feces. DefraTaj is indicated for the treatment of chronic iron overload due to frequent blood transfusions (≥7 ml/kg/month of packed red blood cells) in patients with beta thalassemia major aged 6 years and older. DefraTaj is also indicated for the treatment of chronic iron overload due to blood transfusions when deferoxamine therapy is contraindicated or inadequate in the following patient groups: in patients with beta thalassemia major with iron overload due to frequent blood transfusions (≥7 ml/kg/month of packed red blood cells) aged 2 to 5 years in patients with beta thalassemia major with iron overload due to infrequent blood transfusions