Primidone, Color : White, Form : Powder, Taste : Slightly Bitter

Niksan Pharmaceutical is leading manufacturer and distributer of thePrimidone among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Primidone API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Primidone in the domestic level as well as the international market. 

Niksan Pharmaceutical provides Primidone API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Primidone API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Primidone is one type of antiepileptic medication developed to treat seizures, commonly for partial and generalized seizures.

SYNONYMS: 2-deoxyphenobarbital, Primidon, Primidona, Primidone, Primidonum

IUPAC NAME: 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione

CAS NO: 125-33-7

FORMULA: C₁₂H₁₄N₂O₂

MOLECULAR MASS:218.25 g/mol

STORAGE OF PRIMIDONE : Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

APPLICATIONS OF PRIMIDONE :Primidone is used alone or with other medications to control certain types of seizures. Primidone is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain.

HOW TO USE: Primidone comes as a tablet to take by mouth. It is usually taken 3 to 4 times a day.

HOW PRIMIDONE WORKS: Primidone is used alone or with other medications to control certain types of seizures. Primidone is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain.

CONTRAINDICATIONS OF PRIMIDONE : Primidone is contraindicated in patients who are known to be hypersensitive to barbituric acid derivatives. Contraindications to primidone include patients with a history of porphyria. By inducing the enzymes responsible for porphyrin synthesis, barbiturates may worsen acute porphyria.

PHARMACOKINETICS OFPRIMIDONE: Primidone is well absorbed and distributed throughout the body. Maximum plasma concentration is reached in about 2 h after administration of a 250 mg tablet. Primidone is metabolized in the liver to active metabolites: and phenylethylmalonic acid (PEMA).

SIDE EFFECTS OF PRIMIDONE:  The most common side effect of primidone therapy is sedation and drowsiness. Ataxia, diplopia, and nystagmus occur at the initiation of treatment. Other adverse reactions include dizziness, vertigo, epigastric pain, megaloblastic anemia, respiratory depression, polyuria, skin rash, facial edema.

PRECAUTIONS: Check with your doctor before taking any of the above while you are using this medicine. Primidone may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Even if taken at bedtime, it may cause some people to feel drowsy or less alert on arising.

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