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Contact SupplierSildalist is a combination medication that is not a standard, FDA-approved drug. It is a brand name for a tablet that contains two active ingredients:
Sildenafil Citrate (the active ingredient in )
Tadalafil (the active ingredient in Cialis)
These two ingredients are combined into a single tablet to treat erectile dysfunction (ED).
Mechanism of Action
Both sildenafil and tadalafil belong to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.Their mechanism of action is to increase blood flow to the , which helps to achieve and maintain an erection during sexual arousal.
When a man is sexually stimulated, a chemical called nitric oxide (NO) is released in the .
Nitric oxide activates an enzyme that produces cyclic guanosine monophosphate (cGMP). cGMP causes the smooth muscles in the to relax, allowing blood to flow into the erectile tissues and cause an erection.
The enzyme PDE5 breaks down cGMP, causing the erection to subside.
By inhibiting PDE5, sildenafil and tadalafil allow cGMP to accumulate, leading to prolonged smooth muscle relaxation and improved blood flow.
The combination of both drugs is intended to provide the benefits of each: sildenafil's rapid onset of action and tadalafil's long-lasting effects, which can last for up to 36 hours.
Uses
Sildalist is used to treat erectile dysfunction (impotence) in men.The dual ingredients are meant to help men achieve and maintain an erection for a longer duration compared to a single-ingredient PDE5 inhibitor.
Important Precautions and Side Effects
Because Sildalist contains two powerful PDE5 inhibitors, it is essential to be aware of the potential risks and side effects. Since this is not a medically regulated product, its safety and efficacy may not have been rigorously tested.
Common Side Effects:
Headache
Flushing (reddening of the face)
Nasal congestion
Dizziness
Indigestion or heartburn
Back pain and muscle aches (more common with tadalafil)
Visual disturbances (e.g., blurred vision, a blue tint to vision)
Serious Side Effects (Less Common, but Require Immediate Medical Attention):
Priapism: A prolonged and painful erection lasting more than 4 hours.This can cause permanent damage to the if not treated immediately.
Sudden Vision Loss: A sudden decrease or loss of vision in one or both eyes.
Sudden Hearing Loss: A sudden decrease or loss of hearing, sometimes accompanied by ringing in the ears and dizziness.
Cardiovascular Issues: Sildalist can lower blood pressure.It should never be taken with nitrates (medications for chest pain, such as nitroglycerin), as the combination can cause a life-threatening drop in blood pressure.
Liver and Kidney Problems: Individuals with liver or kidney impairment should exercise extreme caution.