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Contact SupplierGeneral knowledge of goji berry: High glucose-induced barrier impairment of human retinal pigment epithelium is ameliorated by treatment with Goji berry extracts through modulation of cAMP levels Human retinal pigment epithelium cells were used to investigate the mechanisms underlying blood-retinal barrier disruption under conditions of chronic hyperglycemia. The treatment with 25 mM glucose caused a rapid drop in the transepithelial electrical resistance (TEER), which was reversed by the addition of either a methanolic extract from Goji (Lycium barbarum L.) berries or its main component, taurine. Intracellular cAMP levels increased concurrently with the high glucose-induced TEER decrease, and were correlated to an increased activity of the cytosolic isoform of the enzyme adenylyl cyclase. The treatment with plant extract or taurine restored control levels. Data are discussed in view of a possible prevention approach for diabetic retinopathy. Description Best class: Organic goji berry Size250 Organic Goji Berry Organic farming system as far as possiblethe use of available resources in the system of agriculture, in the farmingsystem to encourage and promote biological cycle, including microbial, plantand animal, and make full use of the organic matter and nutrient elements in aclosed system, using agricultural techniques to avoid possible pollution, so asto maintain and improve. Long term fertility goji berry base soil, realize thesustainable development of Chinese