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Contact SupplierSofosbuvir/Velpatasvir (often sold under the brand name Epclusa) is a fixed-dose combination antiviral medication used to treat chronic hepatitis C virus (HCV) infection. It pairs two direct-acting antivirals—sofosbuvir and velpatasvir—in a single oral tablet.
Sofosbuvir is an NS5B RNA-dependent RNA polymerase inhibitor. It blocks a key viral enzyme that the hepatitis C virus needs to replicate its genetic material.