Medical Grade Tacrolimus Ointment, Color : White

Tacroheal Ointment is a brand name for a topical medication containing the active ingredient tacrolimus.It is a type of immunosuppressant, specifically a calcineurin inhibitor, used to treat certain inflammatory skin conditions.

Here is a detailed description of Tacroheal Ointment:

1. Active Ingredient and Mechanism of Action

• Active Ingredient: Tacrolimus.

   

   

• Mechanism: Tacrolimus works by inhibiting an enzyme called calcineurin.This inhibition prevents the activation of certain immune cells (T-cells) that are responsible for causing inflammation and allergic reactions in the skin.By suppressing this immune response, the ointment helps to reduce the symptoms of skin conditions like itching, redness, and inflammation.

   
   
   

   

2. Indications (What it's used for) Tacroheal Ointment is primarily prescribed for:

• Moderate to Severe Atopic Dermatitis (Eczema): It is used for short-term and intermittent long-term management of eczema in adults and children who have not responded well to or cannot tolerate other conventional therapies, such as topical corticosteroids.

   

   

3. Dosage and Administration

• Formulation: It is an ointment for topical use only.

   

   

• Application: A thin layer of the ointment should be applied to the affected areas of clean, dry skin.It should be rubbed in gently and thoroughly.

   
   

   

• Frequency: The typical dosage is twice a day, or as directed by a healthcare professional.

   

   

• Important Instructions:

  • It should not be applied to open wounds or broken skin.

     

     

  • Do not cover the treated area with an occlusive dressing, such as a bandage or wrap, unless specifically instructed by a doctor, as this can increase systemic absorption and the risk of side effects.

     

     

  • Wash hands before and after application, unless the hands are the treated area.

  • The medication should be used for a limited duration and discontinued when the symptoms of eczema have cleared up. If there is no improvement after a certain period (e.g., six weeks), a doctor should be consulted.

     

     

4. Common Side EffectsThe most frequent side effects are local and occur at the application site, especially during the first few days of treatment. These can include:

• Burning or stinging sensation

   

   

• Itching

   

   

• Redness (erythema)

   

   

• Increased skin sensitivity to hot and cold temperatures.

   

   

These side effects often decrease as the skin condition improves. Other possible, but less common, side effects include headache and inflammation of hair follicles.

5. Warnings and Precautions

• Long-Term Use: The long-term safety of tacrolimus ointment is not fully established.There have been rare cases of skin cancer and lymphoma in patients treated with this medication, though a direct causal link has not been proven.For this reason, continuous, long-term use is generally discouraged.

   
   
   

   

• Immune System: Because it is an immunosuppressant, it should be used with caution in patients with a weakened immune system or skin conditions that could increase systemic absorption, such as Netherton's syndrome.

   

   

• Sun Exposure: Tacroheal Ointment can increase sensitivity to sunlight.Patients should avoid or limit sun exposure and use protective clothing and sunscreen while using this medication.

   
   

   

• Alcohol Consumption: Drinking alcohol while using the ointment may cause facial flushing or redness and a feeling of warmth.

   

   

• Pregnancy and Breastfeeding: It is recommended to consult a doctor before using the ointment if you are pregnant, planning to become pregnant, or breastfeeding, as the effects on the fetus or infant are not fully known.

   

   

• Children: It is not recommended for use in children under 2 years of age.For children between 2 and 15 years old, the 0.03% strength is typically used.