Tiamulin Fumarate

We are offering tiamulin fumarate
synonyms: ((2-(diethylamino)ethyl)thio)acetic acid 8-ester with (3as,4r,5s,6s,8r,9r,9ar,10r)-octahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl-3a,9-propano-3ah-cyclopentacycloocten-1(4h)-one fumarate;denagard;,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles;14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate;14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato;81723hfu;dynamutilin;sandoz81723hfu
cas: 55297-96-6
mf: c32h51no8s
mw: 609.81
einecs: 259-581-6
mp 147-148°c
storage temp. 2-8°c
chemical properties white solid
usage tiamulin is a semi-synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity. The hemi-fumarate provides a stable salt with improved water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action of inhibiting protein synthesis by binding to domain v of 23s rrna.
Usage a derivative of pleuromutilin. Antibacterial.