Tolnaftate

We are offering tolnaftate.
Tolnaftate is a synthetic antifungal agent. Tolnaftate is a thiocar- bamate derivative with either fungicidal or fungistatic property. tolnaftate is a selective, reversible and non-competitive inhibitor of membrane-bound squalene-2, 3- epoxidase, and an enzyme involved in the biosynthesis of ergosterol. Inhibition leads to the accumulation of squalene and a deficiency in ergosterol, an essential component of fungal cell walls, thereby increasing membrane permeability, disrupting cellular organization and causing cell death. In addition, this agent may also distort the hyphae and stunts mycelial growth in susceptible fungi.
synonyms: o-naphthalen-2-yl n-methyl-n-(3-methylphenyl) carbamothioate
cas number: 2398-96-1, mol. Formula: c19h17nos, mol.weight: 307.41
tolnaftate is white crystalline powder. It is soluble in water 0.0000702 mgml at 25 °c with melting range of 110.5°c to 111.5°c.
standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements