Troyvit D3 Capsules for Oral Consumption

Cholecalciferol (Vitamin D3) is a BCS – II vitamin with challenges to aqueous solubility which results in low dissolution and limits absorption. As Vitamin D is not completely miscible in water, it cannot be taken with water. To overcome this limitation and to bridge the gap, Troikaa has developed Troyvit D3, a formulation of Cholecalciferol capsules that utilizes the LiquiCaps technology with a Self Emulsifying Drug Delivery System (SEDDS).Troyvit D3 LiquiCaps (Liquid-filled & sealed hard gelatin capsule), are formulated by SEDDS.LiquiCaps are 2-piece hard capsules, filled with oily medicaments & sealed with a band. Nitrogen bubble in the LiquiCaps keeps active ingredient fresh and intact.The major benefits offered by LiquiCaps over soft gelatin capsules include lower microbial load in the thin gelatin shell of LiquiCaps, as compared to the heavy microbial burden in softgels. Furthermore, LiquiCaps disintegrate much faster as compared to softgels & hence release the active ingredient promptly on ingestion.SEDDS converts vitamin D3 into a soluble hydrophilic shell and improves its solubility. SEDDS enables the formation of relatively stable oil-in-water (o/w) emulsions upon aqueous dilution owing to the gentle agitation of the gastrointestinal fluids. When the formulation is released into the lumen of the gut it disperses to form a fine emulsion so that the drug remains in solution in the gut, thereby offering very high surface area for absorption. This helps in quick absorption of the drug and improves oral bioavailability