Ursolic Acid

We are offering Ursolic Acid.
Product name:ursolic acid
plant source:loquat leaf
appearance:white power.
Used:leaf
assay:20%-95% test by hplc
cas no.:77-52-1
molecular formula:c30h48o3
molecular weight:456.68
ursolic acid description
ursolic acid, a carboxylic acid present in a wide variety of plants in the form of a free acid or an aglycone
of triterpene saponins.it is also known as urson, prunol, micromerol, and malol, is a pentacyclic triterpenoid
compound which naturally occurs in a large number of vegetarian foods, medicinal herbs, and plants1,2. For a
long time, it was considered to be pharmacologically inactive3. Thus, ursolic acid and its alkali salts
(e.g. Potassium or sodium ursolates) were exclusively used as emulsifying agents in pharmaceutical, cosmetic,
and food preparations3,4. However, upon closer examination, ursolic acid was found to be medicinally active
both topically and internally1. Its anti-inflammatory, antitumor (skin cancer), and antimicrobial properties make it useful in cosmetic applications1.
ursolic acid [(3b)-3-hydroxyurs-12-en-28-oic acid] rarely occurs without its isomer oleanolic acid [(3b)-3-hydroxyolean-12-en-28-oic acid]. They may occur in their free acid form, as shown in figure 1, or as aglycones for triterpenoid
saponins which are comprised of a triterpenoid aglycone linked to one or more sugar moieties. Ursolic and
oleanolic acids are similar in pharmacological activity1. Several ursolic acid derivatives, both natural
and synthetic, have been reported. Novel ursolic acid derivatives, including ursane-type triterpenoid saponins, naturally occur as secondary metabolites through complex metabolic processes in different parts of the plant5,8-12 synthetic derivatives obtained from ursolic acid have been reported and evaluated for their pharmacological action3,13-16.