Vardenafil

Vardenafil
CAS NO.: 224785-91-5
Molecular Formula: C23H32N6O4S
Molecular weight:525.06
Purity:99%
Suitable for: adult
Certification:GMP, ISO 9001, USP, BP
Appearance: White to almost white crystalline powder, odorless, a little acerbity,
soluble in water, ethanol
Use: It is pharmaceutical raw material, indicated for the treatment of erectile dysfunction.
Description:
Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to citrate and Tadalafil. The difference between the Vardenafil molecule and citrate is that a nitrogen atom has different position and the change of piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both and Vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat lon ger than .
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Furthermore, Vardenafil lengthens the QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as Amiodarone).
Application:
Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from vaginal penetration to ejaculation.
Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure).
Further, Vardenafil causing lengthening of the QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as amiodarone).