Tinidazole, CAS No. : 19387-91-8

Tinidazole is a nitroimidazole antitrichomonal agent effective against trichomonas vaginalis, entamoeba histolytica, and giardia lamblia infections. Tinidazole is a nitroimidazole antimicrobial. The chemical classification of tinidazole is nitroimidazoles.
Tinidazole is a 5-nitroimidazole derivative with antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized & yields nitrite anions & metronidazole. Metronidazole's nitro group in turn is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and dna strand breaks with multiple hits having an additive effect and ultimately leading to cell death.