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Studies have shown that the effectiveness of Zostavax wanes substantially over time, leaving recipients with reduced protection against herpes zoster. Zostavax, a live-attenuated varicella-zoster virus (VZV) vaccine, is used to prevent herpes zoster (shingles) and the long-lasting nerve pain that can follow, known as postherpetic neuralgia, in individuals 50 years of age and older.
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