Moxifloxacin Hydrochloride Is The Hydrochloride Salt Preparation Of Moxifloxacin, An 8-Methoxy-Fluoroquinone Compound With Broad-Spectrum Bactericidal Activity Against Gram-Positive & Gram-Negative Strains. 8-Methoxy-Fluoroquinones Are Described To Inhibit The Activities Of Topo Ii (DNA Gyrase) & Topoisomerase Iv. The 8-Methoxy Group Of Moxifloxacin Is Suggested To Confer A Lowered Propensity For Resistance Development As Compared To Other C-8 Substituted Quinolones, & Moxifloxacin Demonstrates Potent Activity Against Wild-Type And First-Step Gyrase- & Topoisomerase Iv-Resistant Mutants. Moxifloxacin Shows Activity Against Methicillin-Susceptible Staphy Lococci, Penicillin-Susceptible And Penicillin-Resistant Pneumococci, Penicillin-Susceptible & Penicillin-Resistant Viridans Group streptococci, Group A streptococci, m. Catarrhalis, & H. Influenzae in Vitro.
Synonyms : 7-[(4as,7as)-1,2,3,4,4a,5,7,7a-Octahydropyrrolo[3,4-B]Pyridin-6-Yl]-1-Cyclopropyl-6-Fluoro-8-Methoxy-4-Oxoquinoline-3-Carboxylic Acid;Hydrochloride.
Moxifloxacin Hydrochloride is a Slightly Yellow to Yellow Crystalline Substance. It is Sparingly Soluble in Water (24 Mg/ml), Dmso (88 Mg/ml At 25 °c), and Ethanol (<1 Mg/ml At 25 °c) with Melting Ran.

Moxifloxacin Hydrochloride Is The Hydrochloride Salt Preparation Of Moxifloxacin, An 8-Methoxy-Fluoroquinone Compound With Broad-Spectrum Bactericidal Activity Against Gram-Positive & Gram-Negative Strains. 8-Methoxy-Fluoroquinones Are Described To Inhibit The Activities Of Topo Ii (DNA Gyrase) & Topoisomerase Iv. The 8-Methoxy Group Of Moxifloxacin Is Suggested To Confer A Lowered Propensity For Resistance Development As Compared To Other C-8 Substituted Quinolones, & Moxifloxacin Demonstrates Potent Activity Against Wild-Type And First-Step Gyrase- & Topoisomerase Iv-Resistant Mutants. Moxifloxacin Shows Activity Against Methicillin-Susceptible Staphy Lococci, Penicillin-Susceptible And Penicillin-Resistant Pneumococci, Penicillin-Susceptible & Penicillin-Resistant Viridans Group streptococci, Group A streptococci, m. Catarrhalis, & H. Influenzae in Vitro.
Synonyms : 7-[(4as,7as)-1,2,3,4,4a,5,7,7a-Octahydropyrrolo[3,4-B]Pyridin-6-Yl]-1-Cyclopropyl-6-Fluoro-8-Methoxy-4-Oxoquinoline-3-Carboxylic Acid;Hydrochloride.
Moxifloxacin Hydrochloride is a Slightly Yellow to Yellow Crystalline Substance. It is Sparingly Soluble in Water (24 Mg/ml), Dmso (88 Mg/ml At 25 °c), and Ethanol (<1 Mg/ml At 25 °c) with Melting Ran.