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Biguanides + Sulfonyl Urea

Our product range contains a wide range of Metformin Hydrochloride Sr Glimipiride Tablets, Glimepiride Metformin Hcl Pioglitazone and Metformin 1000 Mg + Glimipiride Tablets

Metformin Hydrochloride Sr Glimipiride Tablets

900 - 1,500 / Box Get Latest Price
  • Brand Name Novimet G1/G2
  • Form Tablets
  • Application Clinical, Hospital
  • Grade Allopathic
  • Packaging Type Blister
  • Packaging Size 10*10, 10*15
  • Medicine Type Pharmaceutical.
  • Number Of Flower Metformin Tablets
  • Country of Origin India

Novimet G1/G2 Tablets

Metformin 500 mg + Glimepiride tablets are a combination medication used to manage type 2 diabetes mellitus. This formulation combines two antidiabetic agents: **Metformin**, which belongs to the class of biguanides, and **Glimepiride**, a sulfonylurea.

### **Metformin (500 mg)**:

- **Mechanism**: Lowers blood sugar levels by improving insulin sensitivity, reducing hepatic glucose production, and increasing glucose uptake by muscle cells.

- **Function**: Primarily targets insulin resistance and helps in reducing fasting and postprandial blood glucose levels.

### **Glimepiride**:

- **Mechanism**: Stimulates the pancreas to produce more insulin by enhancing the release of insulin from pancreatic beta cells.

- **Function**: Helps in managing blood sugar levels, particularly by addressing insufficient insulin production.

### **Usage**:

- **Indication**: Primarily prescribed for patients with type 2 diabetes who cannot manage their blood sugar levels adequately through diet and exercise alone.

- **Administration**: Usually taken once or twice daily with meals to reduce the risk of gastrointestinal upset and to enhance absorption.

### **Precautions**:

- **Monitoring**: Regular monitoring of blood sugar levels is necessary to avoid hypoglycemia or hyperglycemia.

- **Side Effects**: Common side effects include gastrointestinal disturbances (nausea, diarrhea), hypoglycemia (especially with improper dosing), and potential allergic reactions. Long-term use of metformin may also affect vitamin B12 levels.

This combination helps to improve overall glycemic control by targeting both insulin resistance (via Metformin) and pancreatic insulin production (via Glimepiride), making it an effective therapy for managing type 2 diabetes.

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Glimepiride Metformin Hcl Pioglitazone

1,950 - 2,700 / Box Get Latest Price
  • Brand Name Novimet GP1/GP2
  • Form Tablets
  • Packaging Size 15*10 Tablets
  • Packaging Type Box
  • Usage Type 2 Diabetes Mellitus
  • Shelf Life 24 Months
  • Country of Origin India

Novimet GP1/GP2 Tablets

**Glimepiride 1 mg + Metformin 500 mg + Pioglitazone 15 mg Tablets**

This combination tablet contains three antidiabetic agentsGlimepiride, Metformin, and Pioglitazoneused to manage blood sugar levels in individuals with type 2 diabetes mellitus.

1. **Glimepiride (1 mg)**: A sulfonylurea that helps lower blood sugar by increasing the release of insulin from the pancreas.

2. **Metformin (500 mg)**: A biguanide that reduces glucose production in the liver and improves the body's sensitivity to insulin, helping to control blood sugar levels.

3. **Pioglitazone (15 mg)**: A thiazolidinedione that enhances insulin sensitivity in muscle and adipose tissue, making it easier for cells to absorb glucose from the bloodstream.

This combination works synergistically to help patients achieve better glycemic control, especially when diet, exercise, or monotherapy is insufficient. It is typically prescribed under medical supervision for the treatment of type 2 diabetes.

**Uses**:

- Type 2 diabetes management

**Dosage**:

Take as directed by a healthcare provider, usually once daily with meals to reduce gastrointestinal side effects.

**Precautions**:

- Regular monitoring of blood sugar levels is recommended.

- Inform your healthcare provider about any history of heart disease, liver problems, or kidney disease.

- This combination may increase the risk of hypoglycemia (low blood sugar) and may not be suitable for all patients.

**Side Effects**:

- Hypoglycemia

- Gastrointestinal discomfort (e.g., nausea, diarrhea)

- Weight gain

- Edema (swelling)

Consult a healthcare professional for personalized advice.

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Metformin 1000 Mg + Glimipiride Tablets

1,200 - 1,300 / Box Get Latest Price
  • Brand Name Novimet G1/G2 Forte
  • Form Tablets
  • Application Clinical, Hospital
  • Grade Allopathic
  • Packaging Type Blister
  • Packaging Size 10*10
  • Medicine Type Pharmaceutical.
  • Country of Origin India

Novimet G1/G2 Forte Tablets

**Metformin 1000 mg + Glimepiride Tablets** are a combination of two antidiabetic medications used to manage type 2 diabetes mellitus. These tablets help control blood sugar levels in patients who cannot achieve adequate glycemic control through diet and exercise alone.

### Active Ingredients:

1. **Metformin (1000 mg)**: Belongs to the class of biguanides, which works by:

- Reducing glucose production in the liver.

- Increasing the body's sensitivity to insulin.

- Improving the uptake and utilization of glucose by muscles.

2. **Glimepiride**: A sulfonylurea that:

- Stimulates the pancreas to release insulin.

- Helps the body to use insulin more effectively.

### Indications:

- Used to treat type 2 diabetes mellitus in adults.

- Helps in reducing the risk of diabetes-related complications when combined with a proper diet and exercise program.

### Dosage:

- The dosage of this combination is typically determined by the physician based on the patient's condition and response to treatment.

### Mechanism of Action:

This combination works by two mechanisms:

1. **Metformin** reduces glucose absorption in the intestines and hepatic glucose production.

2. **Glimepiride** enhances insulin secretion from the pancreatic beta cells and improves the bodys response to insulin.

### Key Benefits:

- Provides effective control over high blood sugar levels.

- Reduces the risk of complications such as heart disease, kidney damage, and nerve problems caused by uncontrolled diabetes.

### Side Effects:

- Common side effects include gastrointestinal discomfort (nausea, diarrhea), hypoglycemia (low blood sugar), dizziness, or weight gain.

### Precautions:

- Should not be used in patients with type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver dysfunction.

- Regular monitoring of blood glucose levels is advised.

- Not recommended during pregnancy or breastfeeding without medical advice.

Always take this medication as prescribed by your healthcare provider and ensure regular follow-up to manage blood sugar effectively.

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