Acute Systemic Toxicity Services

Systemic toxicity studies are conducted to evaluate the adverse effects of a substance on the entire body or specific organ systems following its absorption into the bloodstream. These studies help determine how a substance affects various physiological functions and organ health over time. They are a critical component of safety assessments for a wide range of products and substances.

These studies are important for evaluating the safety of:

• Pharmaceuticals – to ensure drugs do not cause harmful effects at therapeutic doses

• Chemicals – including those used in agriculture, industry, or cleaning products

• Food additives – to verify safety for human consumption over time

• Cosmetics – especially products absorbed through the skin

• Industrial compounds – to assess occupational and environmental exposure risks

Systemic toxicity studies provide essential data for regulatory agencies to set exposure limits, labeling requirements, and usage guidelines to protect human and environmental health.