Lafutidine, Form : Organic Molecular Entity, CAS No. : 118288-08-7

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the LAFUTIDINEfinished formulations moreover LAFUTIDINE API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of LAFUTIDINE API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of
LAFUTIDINE inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the LAFUTIDINE to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.  

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also LAFUTIDINE formulations in many countries for many years. Niksan pharmaceutical currently exports LAFUTIDINE API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

LAFUTIDINEis a histamine H₂-receptor antagonist used mainly for the treatment of gastric ulcers, gastroesophageal reflux disease (GERD), and other acid-related gastrointestinal disorders. It reduces gastric acid secretion and promotes mucosal defense

SYNONYSMS:FRG-8813, (+)-Lafutidine

IUPAC NAME: 2-[[2-[(furanylmethyl)thio]ethyl]amino]-N-[4-(piperidin-1-ylmethyl)phenyl]acetamide

CAS NO:118288-08-7

FORMULA:C22H29N3O4S

MOLECULAR MASS:  431.55 g/mol

STORAGE CONDITIONS:Store Lafutidine in a tightly closed container at room temperature (20°C to 25°C). Keep away from excessive heat, moisture, and direct light.

HOW TO USE:Typical adult dose for peptic ulcer — 10 mg twice daily or as directed by a physician. Dosage may vary depending on the severity of the condition and patient profile.

HOW LAFUTIDINE WORKS:Lafutidine competitively inhibits histamine H₂ receptors on gastric parietal cells, reducing both basal and stimulated gastric acid secretion. It also enhances mucosal blood flow and stimulates mucus secretion, offering gastroprotective effects.

PHARMACOKINETICS OF LAFUTIDINE:

Absorption: Rapidly absorbed after oral administration.

Metabolism: Extensively metabolized in the liver.

Elimination half-life: ~2–4 hours.

Excretion: Mainly through urine as metabolites.

SIDE EFFECTS OF LAFUTIDINE: The normal side effects caused by lafutidine are Headache, diarrhea, constipation, dry mouth, rash, dizziness, or nausea. Rarely: hypersensitivity reactions, liver enzyme elevation.

PRECAUTIONS: Use with caution in patients with renal or hepatic impairment. Not recommended in pregnancy or lactation unless prescribed. Avoid exceeding recommended dose.

CDSCO APPROVAL:

Lafutidine Tablets-5mg/10mg 16.11.09

Lafutidine Tablets-5mg/10mg 19.01.10

FORMULATIONS AVAILABLE IN MARKET:

LAFUTIDINE 10 MG tablets

LAFUTIDINE + DOMPERIDONE tablets/capsules

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

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