Lercanidipine 200MG

Niksan Pharmaceutical is leading manufacturer and distributer of theLercanidipine among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Lercanidipine API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Lercanidipine in the domestic level as well as the international market. 

Niksan Pharmaceutical provides Lercanidipine API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Lercanidipine API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Lercanidipine is a calcium channel blocker medicine used to treat high blood pressure (hypertension). If you have high blood pressure, taking lercanidipine helps prevent heart disease, heart attacks and strokes.

SYNONYMS: Lercanidipine, Lercanidipino

IUPAC NAME: 3-{1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

CAS NO: 100427-26-7

FORMULA: C₃₆H₄₁N₃O₆

MOLECULAR MASS:611.72 g/mol

STORAGE OF LERCANIDIPINE:Store below 30°C. Protect from light and moisture. C08CA13 - lercanidipine; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.

APPLICATIONS OF LERCANIDIPINE:Lercanidipine is used to treat high blood pressure. Your GP may also prescribe it to prevent: heart disease. heart attacks.

HOW TO USE: It's best to take lercanidipine in the morning but you can take it at any time of day. Try to make sure you take it at the same time every day. Take lercanidipine on an empty stomach, at least 15 minutes before a meal.

HOW LERCANIDIPINE WORKS: Lercanidipine is a type of medicine called a calcium channel blocker. Like other calcium channel blockers, lercanidipine works by blocking calcium going into muscles in the heart and blood vessels. Muscles need calcium to contract, so when you block the calcium, it makes the muscle cells relax and widen.

CONTRAINDICATIONS OF LERCANIDIPINE: Lercanidipine is contraindicated in patients with severe hepatic impairment or renal impairment (GFR < 30 ml/min), including patients undergoing haemodialysis (see section 4.2 and section 4.3). Lercanidipine has been associated with the development of cloudy peritoneal effluent in patients on peritoneal dialysis.

PHARMACOKINETICS OFLERCANIDIPINE: Lercanidipine is slowly but completely absorbed from the gut. It has a total bioavailability of 10% due to an extensive first-pass effect, or up to 40% if taken after a fatty meal. Highest blood plasma levels are reached after 1.5 to 3 hours.

SIDE EFFECTS OF LERCANIDIPINE:  Headaches. Make sure you rest and drink plenty of fluids, Reddening of your face, neck or chest (flushing) This usually happens when you first start taking lercanidipine, A fast, pounding or irregular heartbeat (palpitations), Swollen ankles (oedema)

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