Listing ID #4370829
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Contact SupplierMicrocrystalline Cellulose is a purified, partly depolymerised cellulose with shorter, crystalline polymer chains. Its strong binding performance make MCC one of the most commonly used fillers and binders in drug formulations, together with Lactose. The product is manufactured by controlled partial hydrolysis of high purity wood pulp, followed by purification and drying.
These grades are ideally suited to be used in the majority of tablet and capsule formulations processed by direct compression, capsule filling, wet granulation, dry granulation or extrusion-spheronisation. While KEVICEL PH 101 is mainly applied in wet granulation and extrusion-spheronisation, KEVICEL PH 102 and KEVICEL PH 112 possess excellent properties for use in direct compression processes. KEVICEL PH 112 is recommended for application in formulations with moisture sensitive drugs, due to its low moisture content.
GRADE | |||||||
Grade | PARTICLE SIZE DISTRIBUTION | BULK DENSITY (gm/ml) |
MOISTURE (%W/W) |
DOP | |||
D10(MIC) | D50(MIC) | D90(MIC) | APS(MIC) | ||||
KEVICEL 101 | NMT 30 | 40-60 | NLT 80 | 50 | 0.27-0.34 | 3.0-5.0 | 200-250 |
KEVICEL 102 | NMT 45 | 70-100 | NLT 40 | 90 | 0.26-0.34 | 3.0-5.0 | 200-250 |
KEVICEL 112 | NMT 45 | 70-100 | NLT 140 | 50 | 0.26-0.34 | 0.0-1.5 | 200-250 |
KEVICEL 200 | NMT 70 | 150-200 | NLT 260 | 180 | 0.31-0.39 | 3.0-5.0 | 200-250 |