Microcrystalline Cellulose

Total molds & yeast countNMT 1000 cfu/g
Ether soluble substancesNMT 0.05%
Sulphated ashNMT 0.10 %
Assay(Dried)97.00 to 102.00%
Supply TypeManufacturer, Exporter, Supplier, Retailer
Preferred Buyer Location All over the world

Product Details

Assay(Dried)97.00 to 102.00%
S.Aureus & P.AeruginosaAbsent in 1g.
E.Coli & SalmonellaAbsent in 10g.
Total molds & yeast countNMT 1000 cfu/g
Total viable aerobic countNMT 1000 cfu/g
Loss on Drying<7%
Heavy metals , limit testLead <0.5 ppm, Arsenic <1 ppm, Mercury < 1ppm, Cadmium < 0.5
ConductivityNMT 75 μS.cm-1
Identification a) Zinc chloride test b) Degree of polymerisationa) Violet Blue Colour b) NMT 350
Ether soluble substancesNMT 0.05%
pH5.00 to 7.50
Water soluble substancesNMT 0.25%
SolubilityPractically insoluble in water, acetone, anhydrous ethanol, toluene, dilute acids & in a 50g/l solution of sodium hydroxide.
Sulphated ashNMT 0.10 %

Microcrystalline Cellulose is a purified, partly depolymerised cellulose with shorter, crystalline polymer chains. Its strong binding performance make MCC one of the most commonly used fillers and binders in drug formulations, together with Lactose. The product is manufactured by controlled partial hydrolysis of high purity wood pulp, followed by purification and drying.

These grades are ideally suited to be used in the majority of tablet and capsule formulations processed by direct compression, capsule filling, wet granulation, dry granulation or extrusion-spheronisation. While KEVICEL PH 101 is mainly applied in wet granulation and extrusion-spheronisation, KEVICEL PH 102 and KEVICEL PH 112 possess excellent properties for use in direct compression processes. KEVICEL PH 112 is recommended for application in formulations with moisture sensitive drugs, due to its low moisture content.

Specifications Of Micro Crystalline Cellulose

GRADE
Grade	PARTICLE SIZE DISTRIBUTION				BULK DENSITY (gm/ml)	MOISTURE (%W/W)	DOP
Grade	D10(MIC)	D50(MIC)	D90(MIC)	APS(MIC)	BULK DENSITY (gm/ml)	MOISTURE (%W/W)	DOP
KEVICEL 101	NMT 30	40-60	NLT 80	50	0.27-0.34	3.0-5.0	200-250
KEVICEL 102	NMT 45	70-100	NLT 40	90	0.26-0.34	3.0-5.0	200-250
KEVICEL 112	NMT 45	70-100	NLT 140	50	0.26-0.34	0.0-1.5	200-250
KEVICEL 200	NMT 70	150-200	NLT 260	180	0.31-0.39	3.0-5.0	200-250