Sumatriptan Succinate, CAS No. : 103628-46-2, Purity : 98%

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the SUMATRIPTAN SUCCINATEfinished formulations moreover SUMATRIPTAN SUCCINATE API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Sumatriptan Succinate API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of
Sumatriptan Succinate inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Sumatriptan Succinate to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.  

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Sumatriptan Succinate formulations in many countries for many years. Niksan pharmaceutical currently exports Sumatriptan Succinate API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

SUMATRIPTAN SUCCINATE belongs to a group of medicines called triptans, or serotonin (5-HT1) agonists. We do not yet understand what causes migraines and cluster headaches. However, your symptoms may be due to the temporary widening of blood vessels in your head.

SYNONYSMS: Sumatriptanum ,  ,  

FORMULA:C14H21N3O2S · C4H6O4

MOLECULAR MASS:  413.49 g/mol

STORAGE CONDITIONS:Sumatriptan succinate should be stored at room temperature, away from heat, moisture, and direct light. It's crucial to keep the container tightly closed and stored in a cool, well-ventilated area. Avoid storing it near sources of ignition or incompatible materials like strong acids or bases. 

HOW TO USE: Usually inject it into your thigh. The medicine generally works in 10 to 15 minutes. If your headache improves but then comes back, you can inject another dose after 1 hour. If the first sumatriptan injection does not help, do not have another one for the same attack.

HOW SUMATRIPTAN SUCCINATE WORKS:Sumatriptan acts as an agonist on 5-HT1B/1D receptors by inducing vasoconstriction in the basilar artery and blood vessels within the dura mater. The drug reduces peripheral nociception either by selective cranial vasoconstriction or by affecting trigeminovascular nerves.

PHARMACOKINETICS OF SUMATRIPTAN SUCCINATE:Sumatriptan has a volume of distribution of 50±8L for a 6mg subcutaneous dose ⁷, or 2.7L/kg. Sumatriptan is 14%-21% bound to protein in circulation. Sumatriptan is predominantly metabolized by monoamine oxidase A ^{7,10,8,10,5,9}. The main metabolites are the inactive indole acetic acid and indole acetic acid glucuronide.

SIDE EFFECTS OF SUMATRIPTAN SUCCINATE: The normal side effects caused by SUMATRIPTAN SUCCINATE are flushing, tingling feeling, feeling warm or cold, drowsiness, tiredness, weakness, dizziness, upset stomach, diarrhea, nausea, muscle cramps.

PRECAUTIONS: Tell your doctor if you are allergic to the medicine. Sumatriptan should not be taken while you are using certain other medicines. Before taking sumatriptan, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.