Other Products / Services #3275455

Mometasone Is A Medium-potency Synthetic Corticosteroid With Antiinflammatory, Antipruritic And Vasoconstrictive Properties. Mometasone Provides A Favorable Ratio Of Topical To Systemic Activity Due To Its Primary Local Effect Along With The Extensive Hepatic Metabolism And The Lack Of Active Metabolites. Though  It Is Effective For Treatment Of Asthma, Glucocorticoids Do Not Affect Asthma Symptoms Immediately. Maximum Improvement In Symptoms Following Inhaled Administration Of Mometasone Furoate. Antiinflammatory Actions Of Corticosteroids Are Thought To Involve Phospholipase A2 Inhibitory Proteins, Lipocortins, Which Control The Biosynthesis Of Potent Mediators Of Inflammation Such As Prostaglandins And Leukotrienes. Mometasone Furoate Is Used In The Treatment Of Inflammatory Skin Disorders (Such As Eczema And Psoriasis)(Topical Form) , Allergic Rhinitis (Topical Form) (Such As Hay Fever), Asthma (Inhalation Form)  For Patients Unresponsive To Less Potent Corticosteroids And Penile Phimosis. In Terms Of Steroid Strength, It Is More Potent Than Hydrocortisone And Less Potent Than Dexamethasone.

Details

• Synonyms - 9a, 21-dichloro-11b, 17-dihydroxy-16a -methylpregna-1, 4-diene-3, 20-dione 17-(2-furoate)                                                                                
• Cas Number - 83919-23-7
• Mol.Formula - C27h30cl2o6
• Mol.Weight - 521.44
• Mometasone Furoate Monohydrate Is A White Crystalline Powder, Insoluble In Water, Soluble In Acetone & Chloroform, Freely Soluble In
• Tetrahydrofuran. Its Melting Range Is 218°C To 220°C.
• Standard - Offered Of Pharmaceutical Grade BP/USP/EP
• Packing - Offered In Export Worthy Packing Of 5 Kilos Or As Per Our Customer Requirements.

Paracetamol (Acetaminophen) Is Used To Treat Many Conditions Such As Headache, Muscle Aches, Arthritis, Backache, Toothaches, Colds And Fevers. Paracetamol Is Widely Used Over The Counter. It Is Commonly Used To Help With Headaches, Other Minor Aches And Pains, And Is A Major Ingredient In Many Cold Medications. In Combination With Opioid Analgesics, Paracetamol Is Used In The Management Of More Severe Pain Such As Post-surgical And Cancer Pain. Though Paracetamol Is Used To Treat Inflammatory Pain, It Is Not Classified As An Nsaid Because It Exhibits Only Weak Anti-inflammatory Activity. Paracetamol Is Not Considered Carcinogenic At Therapeutic Doses. It Is Classified As A Mild Analgesic. It Is Also Used As An Intermediate For Pharmaceuticals(As A Precursor In Penicillin) And Azo Dyes, Stabilizer For Hydrogen Peroxide, Photographic Chemicals.

Details

• Synonyms - N-(4-hydroxyphenyl) Acetamide.
• Cas Number - 103-90-2
• Mol. Formula - Ch3conhc6h4oh
• Mol. Weight - 151.17
• It Is An Odorless, Slightly Bitter Taste White Crystalline Powder With Melting Range 169°c-172°c.it Is Soluble In Organic Solvents Such As Methanol And Ethanol But Slightly Soluble In Water And Ether.
• Standard - Offered Of Pharmaceutical Grade BP/USP/EP
• Packing - Offered In Export Worthy Packing Of 25 Kilos Or As Per Our Customer Requirements.

Turmeric is A diarylheptanoid. About Two Centuries Ago, Isolation of a “yellow Coloring-matter” from the Rhizomes of Curcuma Longa (turmeric) & Was Named Curcumin.  Turmeric's other Two Curcuminoids are Desmethoxycurcumin and bis-desmethoxy- Curcumin. the Curcuminoids Are natural Phenols that are Responsible for the Yellow Color of Turmeric. Curcumin Can Exist in Several Tautomeric forms, Including a 1, 3-diketo form and Two Equivalent Enol Forms. the Enol Form is More Energetically Stable in the Solid Phase and in Organic Solvents, While in Water the 1, 3-diketo dominates. Curcumin Can Be Used For boron Quantification in the Curcumin Method. It Reacts With boric Acid to Form a Red-color Compound, Rosocyanine. Curcumin is a Bright-yellow Color Powder and May Be Used as A food Coloring. Curcumin is Powerful Anti-inflammatory Effects and is a Very Strong Antioxidant. Combat Cancer Stem Cells and Enhance Heart Health and Inhibit the Formation of Ldl (bad) Cholesterol.

 

Details :

• Synonyms -  (1e, 6e)-1, 7-bis (4-hydroxy-3-methoxyphenyl) Hepta-1, 6-diene-3, 5-dione
• Cas Number -  458-37-7
• Mol. Formula -  C21h20o6
• Mol. Weight: 368.38.
• It is Orange Crystalline Powder with Its Melting Point of 183 °C. It is Slightly Soluble in Hot Water
• Standard -  Offered of Pharmaceutical Grade.
• Packing -  Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements.

Artesunate is a water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-shistosomiasis, antiviral, and potential anti-neoplastic activities. Upon hydrolysis of artesunate's active endoperoxide bridge moiety by liberated heme in parasite-infected red blood cells, reactive oxygen species and carbon-centered radicals form, which have been shown to damage and kill parasitic organisms. Additionally, in vitro studies demonstrate that this agent induces dna breakage in a dose-dependent manner. Artesunate has also been shown to stimulate cell differentiation, arrest the cell cycle in the g1 and g2m phases, inhibit cell proliferation, and induce apoptosis through mitochondrial and caspase signaling pathways. Artemisinin is isolated from the plant artemisia annua. Artesunate is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection.

Pheniramine maleate is antihistamine with anticholinergic properties used to treat allergicconditions such as hay fever or urticaria. Its relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine. Pheniramine is also commonly found in eyedrops used for the treatment of allergic conjunctivitis.Pheniramine is generally sold in combination with other medications, rather than as a stand-alone drug, although some formulations are available containing pheniramine by itself. One of this histamine h1 antagonist with little sedative action. Pheniramine maleate is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus.

Bimatoprost is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension.Bimatoprost is a prostaglandin analog. The chemical classification of bimatoprost is prostaglandins.

Rizatriptan is a serotonin-1b and serotonin-1d receptor agonist. The mechanism of action of rizatriptan is as a serotonin 1b receptor agonist and serotonin 1d receptor agonist. Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxy tryptamine1 receptor subtype agonist.

Chlorzoxazone is a centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. Chlorzoxazone is a muscle relaxant. The physiologic effect of chlorzoxazone is by means of centrally-mediated muscle relaxation.Chlorzoxazone is a benzoxazolone derivative with mild sedative and centrally-acting muscle relaxant activities. Although its exact mechanism of action is unknown chlorzoxazone(cz) appears to act at the spinal cord and subcortical levels of the brain to inhibit multisynaptic reflex arcs involved in producing and maintaining muscle spasms. This agent is extensively hydroxylated by cytochrome p450 2e1 (cyp2e1) to 6-hydroxychlorzoxazone (hcz), 11, 12 which is subsequently glucuronidated and eliminated renally. Highly selective for cyp2e1, cz may be used as a selective probe for phenotyping cyp2e1 in humans; the ratio of hcz-to-cz plasma concentrations obtained 2 to 4 hours after oral administration of cz may be used as a phenotypic measure of cyp2e1 enzymatic activity

We are Offering Various Types of Antioxidants like Tbhq (tertiary Butyl Hydroquinone), Bha (butylated Hydroxy Anisole), Bht (butylated Hydroxy Toluene) Etc. We Can also Supply other Antioxidants On Specific Demand.

TBHQ a Highly Effective antioxidant in Foods, Used as A preservative for Unsaturated vegetable Oils and Many Edible Animal Fats.  It Can Be Combined with other Preservatives such As bha. Its Primary Advantage is Enhancing Storage Life. Synonyms: 2-tert-butylbenzene-1, 4-diol – Cas Number: 1948-33-0, Mol. Formula: C10h14o2, Mol. Weight: 166.22. It is White Crystalline Powder with Its Melting Range of 126°C -129°C. It is Insoluble in Water.

BHA (butylated Hydroxy Anisole) is An antioxidant consisting of a Mixture of Two isomeric organic Compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. It is a Waxy Solid Used as Food Additive, Antioxidant & Preservative in Food, Food Packaging, Animal Feed, Cosmetics, Rubber, and Petroleum Products. bha also is Commonly Used in Medicines, such As isotretinoin, Lovastatin, And simvastatin, among Others.  Synonyms: 2-tert-butyl-4-methoxyphenol;3-tert-butyl-4-methoxyphenol-– Cas Number: 25013-16-5, Mol. Formula: C11h16o2, Mol. Weight: 180.24. It is White to Slightly Yellowpowder with Its Melting Range of 48°c -55°c. It is Insoluble in Water.

BHT (butylated Hydroxytoluene), also Known As dibutylhydroxytoluene, Useful for Its antioxidant properties. It is Used as Food Additive, Household Product Ingredient, Industrial Additive, Personal Care Product/cosmetic Ingredient, Pesticide Ingredient, Plastic/rubber Ingredient and Medical/veterinary/research.

 

Details :

• Synonyms - 2-tert-butyl-4-methoxyphenol; 2, 6-ditert-butyl-4-methylphenol
• Cas Number - 128-37-0
• Mol. Formula: C15h24o
• Mol. Weight - 220.35.
• It is White Crystalline Powder with Its Melting Range of 69°C -73°C. It is Insoluble in Water.
• Standard - Offered of Food Grade FFC
• Packing - Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements.

Zinc sulfate monohydrate can be used in electrolytes for zinc plating. It can be used as a mordant in dyeing. It can also be used in medicine as an astringent and emetic. Zinc sulfate monohydrate can be used to supply zinc in animal feeds, fertilizers, and agricultural sprays.

Diacerein (inn), also known as diacetylrhein, is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis (swelling and pain in the joints). It works by inhibiting interleukin-1 beta. A 2005 cochrane review found diacerein to be slightly, but significantly, more effective than placebo in improving pain and slowing the progress of osteoarthritis in the hip and knee.

Lidocaine is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacaine or prilocaine. Lidocaine is an amide local anesthetic and antiarrhythmic. The physiologic effect of lidocaine is by means of local anesthesia. The chemical classification of lidocaine is amides.Lidocaine is a synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gatedsodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia.

The physiologic effect of levetiracetam is by means of decreased central nervous system disorganized electrical activity.Levetiracetam is a pyrrolidine with antiepileptic activity. The exact mechanism through which levetiracetam exerts its effects is unknown but does not involve inhibitory & excitatory neurotransmitter activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity.

Drotaverine hydrochloride is an antispasmodic, and an analogue of papaverine. Is an antispasmodic drug, used to enhance cervical dilation during childbirth.Drotaverine hydrochloride is structurally related to papaverine, is a selective inhibitor of phosphodiesterase 4, and has no anticholinergic effects.

Mebendazole is a benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. Mebendazole is an antihelminthic.Mebendazole is a synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. This results in a depletion of glycogen stores and leads to reduced formation of atp required for survival and reproduction of the helminth. This eventually causes the helminths death.

Mecobalamin (mecobalamin, mecbl, or meb12) is a cobalamin, a form of vitamin b12. It differs from cyanocobalamin in that the cyanide is replaced by a methyl group. Methylcobalamin features octahedral cobalt (iii) centre. Methylcobalamin can be obtained as bright red crystals. From the perspective of coordination chemistry, methyl cobalamin is notable as a rare example of a compound that contains metal-alkyl bonds. Nickel-methyl intermediates have been proposed for the final step of methanogenesis. Mecobalamin is equivalent physiologically to vitamin b12, and can be used to prevent or treat pathology arising from a lack of vitamin b12 (vitamin b12 deficiency) such as pernicious anemia. Methylcobalamin is also used in the treatment of peripheral neuropathy, diabetic neuropathy & as a preliminary treatment foramyotrophic lateral sclerosis.

Methoxsalen is a naturally occurring furocoumarin compound found in several species of plants, including psoralea corylifolia. It is a photo- active substance that forms dna adducts in the presence of ultraviolet an irradiation. Methoxsalen is a photoactivated radical generator & psoralen. The mechanism of action of methoxsalen is photoabsorption. The physiologic effect of methoxsalen is by means of photosensitizing activity. The chemical classification of methoxsalen is psoralens.Methoxsalen is a naturally occurring substance isolated from the seeds of plant ammi majus with photoactivating properties. As member of the family of compounds known as psoralens or furocoumarins, methox salen's exact mechanism of action is unknown; upon photo-activation, methoxsalen has been observed to bind covalently to & crosslink dna.

Mupirocin is a topically used antibiotic from a strain of pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin disorders, nasal infections, and wound healing. Mupirocin is a rna synthetase inhibitor antibacterial. The mechanism of action of mupirocin is as a rna synthetase inhibitor.Mupirocin is a natural crotonic acid derivative extracted from pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl trna synthase.

Pamidronate disodium is the disodium salt of the synthetic bisphospho- nate pamidronate. Although its mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation.Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase & bone resorption. Studies suggest that pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-b pathway activation, via the endothelial protein c receptor.

Quinine is an alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

Simethicone is a poly (dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base. Simethicone is an orally administered anti-foaming agent used to reduce bloating, discomfort or pain caused by excessive gas mainly swallowed air, with small amounts of hydrogen and methane in the stomach or intestines.

Tamoxifen is an estrogen agonistantagonist. The mechanism of action of tamoxifen is as a selective estrogen receptor modulator one of the selective estrogen receptor modulators with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue but as an estrogen (stimulating agent) in cholesterol metabolism, bone density &cell proliferation in the endometrium.tamoxifen base is an antineoplastic nonsteroidal selective estrogen receptor modulator (serm). Tamoxifen competitively inhibits the binding of estradiol to estro- gen receptors, thereby preventing the receptor from binding to the estrogen-response element on dna. The result is a reduction in dna synthesis & cellular response to estrogen. In additiontamoxifen up-regulates the production of transforming growth factor b (tgfb), a factor that inhibits tumor cell growth & down-regulates insulin-like growth factor 1 a factor that stimulates breast cancer cell growth.

Tropicamide is a machr m4 antagonist (id50=214.20 nmoles) found on blood vessels and neuronal cells. The compound can weaken anti-inflammatory effects and is used in ocular studies. One of the muscarinic antagonists with pharmacologic action similar to atropine and used mainly as an ophthalmic parasympatholytic or mydriatic.

Vincristine is an antitumor alkaloid isolated from vinca rosea. vincristine is an antitumor vinca alkaloid isolated from vinca rosea. It is marketed under several brand names, many of which have different formulations such as marqibo (liposomal injection) and vincasar. vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, hodgkin's disease, acute erythraemia, and acute panmyelosis. Vincristine sulfate is often chosen as part of polychemotherapy because of lack of significant bone-marrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy).

Iron polymaltose complex (ipc) is a non-ionic complex which does not release any free radicals unlike other ionized iron salts iron polymaltose complex (ipc) is a non-ionic complex which does not release any free radicals unlike other ionized iron salts. It is used as an iron supplement, especially in the treatment of iron deficiencies such as anemia and also during pregnancy and lactation period.

Vecuronium bromide is the bromide salt form of vecuronium, a synthetic steroid derivative of the naturally occurring alkaloids of curare with a muscle relaxant property. Vecuronium bromide competes with acetyl- choline for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This leads to skeletal muscle relaxation and paralysis.Monoquaternary homolog of pancuronium a non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.