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UMA Brothers

UMA Brothers
location Mumbai, Maharashtra

gstGST : 27AGPPS8689E1ZF 4.6/5
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Our Products

  1. Medicines Tonics And Drugs 30 Products available
  2. Industrial Acid 29 Products available
  3. Industrial Chemicals 16 Products available
  4. Drugs 15 Products available
  5. Catalysts And Absorbents 13 Products available
  6. Pharmaceutical Raw Materials 11 Products available
  7. Api Intermediate 8 Products available
  8. Pharmaceutical Chemical 8 Products available
  9. Pharmaceuticals Tablets 6 Products available
  10. Pharmaceutical Medicine 5 Products available
  11. Cardiovascular Drugs 3 Products available
  12. Antibiotic Drugs 3 Products available
  13. Anti Hiv Medicines 3 Products available
  14. Ores And Minerals 3 Products available
  15. Antibacterial Drugs 3 Products available
  16. Active Pharmaceutical Ingredients 3 Products available
  17. Anti Inflammatory Drugs 3 Products available
  18. Antihypertensive Drugs 3 Products available
  19. Antihistamines 3 Products available
  20. Anti Diabetic Drugs 3 Products available
  21. Corrosion And Rust Control Products 3 Products available
  22. Vaccines 2 Products available
  23. Psoriasis Ointment 2 Products available
  24. Muscle Relaxant 2 Products available
  25. Micronutrient Fertilizers 1 Products available
  26. Gastrointestinal Drug 1 Products available
  27. Cooking Spices 1 Products available
  28. Anti Cancer Medicine 1 Products available
  29. Mineral Supplements 1 Products available
  30. Pharmaceutical Injectables 1 Products available
  31. Arthritic Drugs 1 Products available
  32. Analgesics 1 Products available
  33. Food Additives 1 Products available
  34. Nervous & Brain System Drugs 1 Products available
  35. Antiepileptic Drugs 1 Products available
  36. Anti Infective Agent 1 Products available
  37. Dietary Supplements 1 Products available
  38. Eye Drops 1 Products available
  39. Osteoporosis Medications 1 Products available
  40. Anti Allergic Drug 1 Products available
  41. Antimigraine Drug 1 Products available
  42. Antimalarial Drugs 1 Products available
  43. Others Products 2 Products available

Drugs

We are leaders in the market for providing best range of Famotidine, Ketorolac Tromethamine Powder, Isoniazid, INDINAVIR and Lisinopril

Famotidine

Famotidine
  • Type Pharmaceutical Raw Material
  • Solubility Soluble in Glacial acetic Acid, Slightly Soluble In methanol, Very Slightly Soluble In water
  • Form Powder
  • Packing 25 Kilos Or As Per Our Customer Requirements
  • color White
  • Standard Grade Pharmaceutical Grade BP/USP/EP

Famotidine is A histamine H2-receptor Antagonist that Inhibits stomach Acid production. It is Commonly Used in the Treatment Of peptic Ulcer disease And gastroesophageal Reflux disease. Unlike cimetidine, the First H2antagonist, Famotidine Has No Effect On The cytochrome P450 enzyme System, and Does Not Appear To interact with other Drugs. Relief Of heartburn, Acid Indigestion, and Sour Stomach Treatment For gastric and duodenal Ulcerstreatment for Pathologic Gastrointestinal Hypersecretory Conditions such As zollinger-ellison Syndrome and multiple Endocrine Adenomastreatment. For gastroeso- Phageal Reflux (gerd)treatment For esophagitis Prevention Of nsaid Induced Peptic Ulcers. Famotidine is also Given to Dogs and Cats with Acid Reflux. famotidine Has Been Used in Combination with An H1 Antagonist to Treat and Prevent Urticaria caused By An Acute Allergic Reaction.

Details

  • Synonyms - 3-[[2-(diaminomethylideneamino)-1, 3-thiazol-4-yl] Methyl Sulfanyl]-n'-sulfamoylpropanimidamide
  • Cas Number - 76824-35-6
  • Mol. Formula - C8h15n7o2s3
  • Mol. Weight - 337.43
  • It is White to Pale Yellow colour Crystals with Melting range of 163°C -164 °C. Freely Soluble in Glacial acetic Acid, Slightly Soluble In methanol, Very Slightly Soluble In water, and Practically Insoluble Inethanol
  • Standard - Offered of Pharmaceutical Grade BP/USP/EP
  • Packing - Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements.

Molecular Structure


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Ketorolac Tromethamine Powder

Ketorolac Tromethamine Powder
  • Min. Order (MOQ) 25 Kilogram

Ketorolac tromethamine is a pyrrolizine carboxylic acid derivative structurally related to indomethacin. It is a non-steroidal anti-inflammatory agent used for analgesia for postoperative pain and inhibits cyclooxygenase activity. Ketorolac tromethamine is the tromethamine salt of ketorolac, a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic & antipyretic properties.ketorolac tromethamine, a non-selective inhibitor of the cyclooxygenases (cox), inhibits both cox-1 & cox-2 enzymes. This agent exerts its anti-inflammatory effect by preventing conversion of arachidonic acid to prostaglandins at inflammation site mediated through inhibition of cox-2, which is undetec- table in most tissues but is up-regulated at the inflammation sites. Since cox-1 is expressed virtually in all tissues, inhibition of cox-1 enzyme by this agent prevents normal state production of prostaglandins, which plays housekeeping roles in the protection of the gastrointestinal tract, regulating renal blood flow, and functioning in platelet aggregation. As a result, inhibition of cox-1 is usually associated with adverse effects such as gastrointestinal toxicity and nephrotoxicity.

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Isoniazid

Isoniazid
  • Min. Order (MOQ) 25 Kilogram
Antibacterial agent used primarily as a tuberculostatic. Isoniazid remains the treatment of choice for tuberculosis. Isoniazid is an antimycobacterial.Isoniazid is a synthetic derivative of nicotinic acid with antimyco bacterial properties. Although mechanism of action is still unclear, isoniazid appears to block the synthesis of mycolic acids, major components of the mycobacterial cell wall.this agent is only active against actively growing mycobacteria because, as a pro-drug, it requires activation in susceptible mycobacterial species. Isoniazid also interferes with mycobacterial metabolism of vitamin b6. Resistance occurs due to decreased bacterial wall penetration.
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INDINAVIR

INDINAVIR
  • Min. Order (MOQ) 25 Kilogram
Indinavir is a potent and specific hiv protease inhibitor that appears to have good oral bioavailability.indinavir anhydrous is a protease inhibitor. The mechanism of action of indinavir anhydrous is as a hiv protease inhibitor.Indinavir anhydrous is an anhydrous formulation of indinavir, a synthetic hydroxyaminopentane amide agent that selectively inhibits the protease of both human immunodeficiency virus 1 and 2. The incorporation of a basic amine into the hydroxyethylene backbone improves its aqueous solubility and its oral bioavailability.
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Lisinopril

Lisinopril
  • Min. Order (MOQ) 25 Kilogram
Lisinopril anhydrous is an angiotensin converting enzyme inhibitor. The mechanism of action of lisinopril anhydrous is as an angiotensin-converting enzyme inhibitor. One of the angiotensin-converting enzyme inhibitors (ace inhibitors), orally active, that has been used in the treatment of hypertension and congestive heart failure.Lisinopril anhydrous is the anhydrous form of the long-acting angiotensin-converting enzyme (ace) inhibitor lisinopril with antihyper- tensive activity. Lisinopril, a synthetic peptide derivative, competitively binds to and inhibits ace, thereby blocking the conversion of angiotensin I to angiotensin ii. This prevents the potent vasoconstrictive actions of angiotensin ii and results in vasodilation. Lisinopril also decreases angiotensin ii-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
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Leflunomide

Leflunomide
  • Min. Order (MOQ) 25 Kilogram
Leflunomide is an antirheumatic agent. Leflunomide is a derivative of isoxazole used for its immunosuppressive and anti-inflammatory properties. As a prodrug, leflunomide is converted to an active metabolite, a77 1726, which blocks dihydroorotate dehydrogenase, a key enzyme of de novo pyrimidine synthesis, thereby preventing the expansion of activated t lymphocytes. This agent also inhibits various protein tyrosine kinases, such as protein kinase c (pkc), thereby inhibiting cell proliferation.
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Famciclovir

Famciclovir
  • Min. Order (MOQ) 25 Kilogram
Famciclovir is a herpes simplex virus nucleoside analog dna polymerase inhibitor. The mechanism of action of famciclovir is as a dna polymerase inhibitor and dna polymerase inhibitor. The chemical classification of famciclovir is nucleoside analog.Famciclovir is a diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral dna by interfering competitively with dna polymerase.
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Naproxen

Naproxen
  • Min. Order (MOQ) 25 Kilogram
Naproxen is an anti-inflammatory agent with analgesic & antipyretic properties. Both the acid & its sodium salt are used in the treatment of rheumatoid arthritis & other rheumatic or musculoskeletal disorders, dysmenorrhea & acute gout. Naproxen is a nonsteroidal antiinflam- matory drug. The mechanism of action of naproxen is as a cyclooxy- genase inhibitor. The chemical classification of naproxen is nonsteroidal anti-inflammatory compounds.Naproxen is a propionic acid derivative and a non-steroidal antiinflam- matory drug with anti-inflammatory, antipyretic & analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and ii, resulting in a decreased formation of precursors of prosta- glandins & thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. naproxen also causes a decrease in the formation of thromboxane a2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
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Nelfinavir

Nelfinavir
  • Min. Order (MOQ) 25 Kilogram
Nelfinavir is a potent hiv protease inhibitor. It is used in combination with other antiviral drugs in the treatment of hiv in both adults and children. Nelfinavir is a protease inhibitor. The mechanism of action of nelfinavir is as a hiv protease inhibitor. Nelfinavir is a synthetic antiviral agent that selectively binds to and inhibits human immunodeficiency virus (hiv) protease. Nelfinavir has activity against hiv 1 and 2. Nelfinavir mesylate is an inhibitor of hsp90.
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Tolnaftate

Tolnaftate
  • Min. Order (MOQ) 25 Kilogram
Tolnaftate is a synthetic antifungal agent. Tolnaftate is a thiocar- bamate derivative with either fungicidal or fungistatic property. tolnaftate is a selective, reversible and non-competitive inhibitor of membrane-bound squalene-2, 3- epoxidase, and an enzyme involved in the biosynthesis of ergosterol. Inhibition leads to the accumulation of squalene and a deficiency in ergosterol, an essential component of fungal cell walls, thereby increasing membrane permeability, disrupting cellular organization and causing cell death. In addition, this agent may also distort the hyphae and stunts mycelial growth in susceptible fungi.
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Torasemide

Torasemide
  • Min. Order (MOQ) 25 Kilogram
Torasemide is a loop diuretic. The physiologic effect of torsemide is by means of increased diuresis at loop of henle. Torasemide is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and has a relatively long half-life.
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Valacyclovir Hydrochloride

Valacyclovir Hydrochloride
  • Min. Order (MOQ) 25 Kilogram
Valacyclovir is a herpes simplex virus nucleoside analog dna polymerase inhibitor, herpes zoster virus nucleoside analog dna polymerase inhibitor & herpesvirus nucleoside analog dna polymerase inhibitor. The mechanism of action of valacyclovir is as a dna polymerase inhibitor. The chemical classification of valacyclovir is nucleoside analog. Valacyclovir is the hydrochloride salt of the l-valyl ester of the antiviral drug acyclovir. Orally administered, valacyclovir is rapidly converted to acyclovir which inhibits viral dna replication after further conversion to the nucleotide analog acyclovir triphosphate by viral thymidine kinase, cellular guanyl cyclase, and a number of other cellular enzymes.acyclovir triphosphate competitively inhibits viral dna polymerase; incorporates into and terminates the growing viral dna chain; and inactivates viral dna polymerase. The greater antiviral activity of acyclovir against herpes simplex virus (hsv) compared with varicella-zoster virus (vzv) is due to its more efficient phosphorylation by hsv thymidine kinase.
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Valdecoxib

Valdecoxib
  • Min. Order (MOQ) 25 Kilogram
Valdecoxib is a sulfonamide derivative and non-steroidal anti-inflammatory drug (nsaid) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (cox)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This nsaid does not inhibit cox-1 at therapeutic concentrations and therefore does not interfere with blood coagulation.
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LOMUSTINE

LOMUSTINE
  • Min. Order (MOQ) 25 Kilogram
Lomustine is an alkylating agent of value against both hematologic malignancies and solid tumors. Lomustine is an alkylating drug. The mechanism of action of lomustine is as an alkylating activity.Lomustine is a nitrosourea with antineoplastic activity. lomustine alkylates and crosslinks dna, thereby inhibiting dna and rna synthesis. This agent also carbamoylates dna and proteins resulting in inhibition of dna & rna synthesis and disruption of rna processing. Lomustine is lipophilic and crosses the blood-brain barrier.
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