Medical Implants

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Implantation Service

Implantation testing is a critical procedure used to evaluate the local biological effects of medical device materials when surgically implanted into living tissue. This study is essential for assessing the biocompatibility of materials that come into prolonged contact with body tissues, ensuring they do not cause harmful reactions.

The test involves implanting the material—often subcutaneously or into muscle—and monitoring the surrounding tissue over time. Key tissue responses observed include:

Inflammation – an immune reaction to the foreign material
Fibrosis – the development of fibrous tissue around the implant
Tissue integration or rejection – indicating healing or adverse reaction

These observations help determine if the material is safe and suitable for long-term use in medical devices such as pacemakers, orthopedic implants, or surgical sutures. Implantation testing is a vital part of preclinical safety assessment in accordance with international biocompatibility standards like ISO 10993.

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