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Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure).Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischaemic heart More..
Telmisartan is indicated in the treatment of essential hypertension.The substance is quickly but to varying degrees absorbed from the gut. The average bioavailability is about 50% (42100%). Food intake has no clinically relevant influence on the kinetics of telmisartan. Plasma protein binding is over 99.5%, mainly to albumin and alpha-1-acid glycoprotein.It has the longest half-life of any ARB (24 hours)and the largest volume of distribution among ARBs (500 liters).Less than 3% of telmisartan is inactivated by glucuronidation in the liver, and over 97% is eliminated in unchanged form via bile and faeces
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Amlodipine is used in the management of hypertension[and coronary artery disease in people with either stable angina (where chest pain occurs mostly after physical or emotional stress)or vasospastic angina (where it occurs in cycles) and without heart failure. It can be used as either monotherapy or combination therapy for the management of hypertension or coronary artery disease. Amlodipine can be administered to adults and children 617 years of age.
Mr. Divyesh Patel (Athos Chemicals)
307, Blu Eminence, Jahangirpura, Dandi Road, Opposite Sangini Gardenia , Surat 395005, Gujarat
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