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Our product range contains a wide range of Dabrafenib Capsules 75mg, Ivermectin Tablet, Nindanib 150mg Soft Gelatin Capsule, Ivermectin Tablets and Sicriptin Tablets
Dabrafenib, sold under the brand name Tafinlar, is a targeted therapy drug used to treat certain types of cancer that have a specific genetic mutation. It is available in capsule form, including a 75mg strength.
Uses
Dabrafenib is a powerful anti-cancer medication used to treat:
Melanoma: It is used either alone or, more commonly, in combination with another drug called trametinib (Mekinist), to treat melanoma (skin cancer) that has spread or cannot be removed by surgery. It is also used with trametinib to help prevent melanoma from returning after surgery.
Non-Small Cell Lung Cancer (NSCLC): It is used in combination with trametinib to treat NSCLC that has spread to other parts of the body.
Anaplastic Thyroid Cancer (ATC): It is used in combination with trametinib to treat ATC that has spread.
Solid Tumors and Low-Grade Glioma: It is also used in combination with trametinib to treat certain other solid tumors and brain tumors (low-grade glioma) in both adults and children.
Important Note: Dabrafenib is only effective in cancers that have a specific genetic mutation, known as the BRAF V600E or V600K mutation. Doctors will perform a specific test on the tumor to confirm the presence of this mutation before prescribing the medication.
Mechanism of Action
Dabrafenib is a type of medicine known as a kinase inhibitor. It specifically targets and blocks the activity of a mutated protein called BRAF. In healthy cells, the BRAF protein is part of a signaling pathway that controls cell growth. However, in cancers with the BRAF V600 mutation, this pathway is overactive, causing cells to grow and divide uncontrollably. By inhibiting this mutated BRAF protein, dabrafenib helps to slow or stop the growth and spread of the cancer cells. When used in combination with trametinib (which targets a different part of the same pathway), the treatment is often more effective and helps to prevent the cancer from developing resistance to the drug.
Administration
Dabrafenib capsules are taken orally, usually twice a day, at evenly spaced intervals (approximately 12 hours apart). The capsules should be swallowed whole with water and should not be crushed, chewed, or opened. It's generally recommended to take dabrafenib on an empty stomach, at least one hour before or two hours after a meal, to maximize absorption. The dosage can vary and may be adjusted by your doctor based on your body weight and how well you tolerate the medication.
Side Effects
As a potent anti-cancer medication, dabrafenib can cause a variety of side effects. When used in combination with trametinib, some side effects may be more frequent or severe. Common side effects include:
Fever and Chills: This is a very common side effect.
Skin Issues: Rash, dry skin, and a thickening of the skin (hyperkeratosis) are common.
Gastrointestinal Issues: Nausea, vomiting, diarrhea, and abdominal pain.
Fatigue and Headache
Joint and Muscle Pain
More serious, but less common, side effects can occur. You should contact your doctor immediately if you experience:
New or Worsening Skin Lesions: Dabrafenib can, in rare cases, lead to the development of new skin cancers. Your skin will be monitored closely by your doctor.
Fever: High fevers may require interrupting treatment.
Cardiomyopathy: Reduced heart function, which can be monitored with regular scans of the heart.
Eye Problems: Swelling in the eye (uveitis), blurred vision, or other vision changes.
Bleeding or Bruising: Dabrafenib can increase the risk of bleeding.
Liver Problems: Symptoms of liver damage, such as yellowing of the skin or eyes (jaundice).
Your doctor will explain how to take Ivermect 12mg Tablet and how much you need. Read the instructions that come with the medicine to make sure you take it correctly. Generally, it is taken on an empty stomach. You usually need to take it only once to get rid of your infection. However, if you do not feel better after taking it, talk to your doctor. To get the most benefit from the medicine, drink lots of fluids and avoid caffeine when taking this medication.
This medicine is generally safe with little or no side effects. Your doctor may get stool and blood tests after taking the medication to see if you have gotten rid of the infection. Remember before taking it, you should ask your doctors advice if you are pregnant or breastfeeding.
Additional Information:
Payment Terms : L/C, D/A, D/P, T/T, Western Union,
Packaging Details : 10*10 TABLETS IN A BOX.
Delivery Time : 7 DAYS
Additional Information:
Payment Terms : L/C, D/A, D/P, T/T, Western Union,
Packaging Details : 10 CAPSULES IN A STRIPS AND 30 CAPSULES IN A BOX.
Delivery Time : 7 DAYS
Ivermectin 12 mg is a medication primarily used as an antiparasitic agent. Here 's a description covering its uses, mechanism of action, and some common aspects:
What it is:
Ivermectin 12 mg is an oral tablet containing 12 milligrams of the active pharmaceutical ingredient ivermectin.
It belongs to a class of medicines known as ectoparasiticides or anthelmintics.
Primary Uses: Ivermectin is approved to treat various parasitic infections in humans, including:
Strongyloidiasis (intestinal threadworm infection): It helps eliminate the parasites from the intestinal tract.
Onchocerciasis (river blindness): It targets the larval forms of the worm that causes this eye and skin infection. While it kills developing worms, it doesn 't treat adult worms, so repeat doses are often needed.
Scabies: It 's effective in treating scabies, a skin infection caused by mites.
Head lice: It can be used to treat head lice, especially when other treatments are not effective.
Lymphatic Filariasis: It 's also used in the management of lymphatic filariasis.
How it Works: Ivermectin works by binding to the muscle and nerve cells of parasites, causing their paralysis and eventual death. This leads to the elimination of the parasite from the body and treats the infection.
Dosage and Administration:
The dosage of Ivermectin 12 mg (or other strengths) is typically based on body weight and the specific parasitic infection being treated.
It is usually taken as a single dose on an empty stomach with a full glass of water.
In some cases, especially for onchocerciasis, repeat doses may be required after a few months (e.g., every 3 to 12 months).
It 's crucial to take the medicine exactly as directed by a doctor and not to self-medicate or alter the dose.
Common Side Effects: While generally well-tolerated, some common side effects can include:
Nausea
Diarrhea
Dizziness
Headache
Rash
Itching
Muscle pain or stiffness
Joint pain
Swollen lymph nodes
Important Considerations:
Not for children weighing less than 15 kg: Ivermectin is generally not recommended for use in children weighing less than 15 kilograms.
Pregnancy and Breastfeeding: Consult a doctor if pregnant or breastfeeding.
Drug Interactions: Inform your doctor about all other medications you are taking, including sedatives, anti-anxiety, or anti-epileptic drugs, as ivermectin can interact with them.
Mazzotti Reaction: In patients treated for river blindness, a severe allergic response called a Mazzotti reaction can occur, characterized by fever, itching, joint pain, etc.
Liver/Kidney Problems: Patients with liver or kidney diseases may experience prolonged drug presence in their system, potentially leading to more side effects.
No COVID-19 Treatment: It 's important to note that ivermectin is not an approved or effective treatment for COVID-19, and its use for this purpose is strongly discouraged by health authorities.
Additional Information:
Payment Terms : L/C, D/A, D/P, T/T, Western Union,
Packaging Details : 10*10 Tablets in a box.
Delivery Time : 7 days
Sicriptin Tablets contain the active ingredient Bromocriptine Mesylate. It belongs to a class of drugs called dopamine agonists and ergot derivatives. This medication is used for a variety of conditions, primarily those related to hormonal imbalances and neurological disorders.
Mechanism of Action
Bromocriptine works by mimicking the effects of dopamine, a neurotransmitter in the brain. It activates dopamine receptors, particularly D2 receptors, which helps regulate various bodily functions, including hormone release.
Key Uses
Sicriptin is prescribed for several different conditions, which are often caused by imbalances in prolactin and growth hormone levels. These include:
Hyperprolactinemia: This is a condition of abnormally high levels of the hormone prolactin in the blood. In women, this can lead to irregular or absent menstrual periods, infertility, and unwanted breast milk production (galactorrhea). In men, it can cause low libido and erectile dysfunction. Sicriptin works by reducing prolactin levels.
Acromegaly: This is a hormonal disorder resulting from an excess of growth hormone in adults, which can cause the abnormal enlargement of bones in the hands, feet, and face. Sicriptin helps by lowering the amount of growth hormone in the body.
Parkinson's Disease: As a dopamine agonist, Sicriptin is used to treat Parkinson's disease, which is caused by a deficiency of dopamine in the brain. It helps to improve motor symptoms like tremors, stiffness, and slow movement.
Lactation Suppression: It can be used to stop breast milk production in women after a stillbirth, miscarriage, or abortion.
Dosage and Administration
The dosage of Sicriptin is highly dependent on the condition being treated and is determined by a doctor. It is typically taken orally with food to reduce side effects like nausea and stomach upset. It is important to take the tablets exactly as prescribed and not to stop the medication suddenly without consulting a doctor, as this can lead to withdrawal effects.
Side Effects
Common side effects of Sicriptin are often mild and may include:
Nausea and vomiting
Headache
Dizziness or lightheadedness, especially when standing up (orthostatic hypotension)
Constipation
Fatigue or drowsiness
Nasal congestion
More serious, but less common, side effects can occur. Patients should seek immediate medical attention if they experience:
Hallucinations or confusion
Uncontrolled body movements
Changes in vision
Severe hypotension (very low blood pressure)
Signs of liver problems, such as yellowing of the skin or eyes.
Important Considerations
Prescription-only: Sicriptin is a powerful medication and should only be taken under the supervision of a healthcare professional.
Blood Pressure: It is known to cause changes in blood pressure, so patients should have their blood pressure monitored regularly, especially when starting the medication or changing the dose.
Pregnancy and Breastfeeding: Sicriptin is generally not recommended for breastfeeding women as it suppresses lactation. Its use during pregnancy should be carefully discussed with a doctor, and it is only prescribed if the benefits outweigh the risks.
Alcohol: Alcohol consumption should be avoided while taking Sicriptin, as it can increase the risk of side effects
Additional Information:
Payment Terms : L/C, D/A, D/P, T/T, Western Union,
Packaging Details : 1*10 tablets in a box
Delivery Time : 7 DAYS
Mr. Tarun Kumawat (Marshall Healthcare)
12 Suvarna Residency Behind Sanidhya Flora TP 76/b, Chandkheda, Ahmedabad, Gujarat - 382424
https://www.marshallhealthcares.com
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