PRISM PHARMA MACHINERY

Vatva, Ahmedabad, Gujarat

Application & Process:
	The prism compact NewLABOfbd- Fluid Bed Dryer model Fluid bed technology is a offer an effective and efficient method for drying and agglomerating. The Lab Fluid Bed Dryer has universal application for drying of powder and granules.The overall concepts of the NewLABOfbd stream from similar of process based on production model and common needs of consistent processing and ease for operation and cleaning. The Drying process:Warm air is blown through a perforated distributor to rapidly and gently dry materials until the required residual moisture content is reached. Moisture evaporated from product is exhausted with drying air.
	New Design Features:
	Designed strictly compliance with the stipulation of cGMP. Product contact parts AISI 316 / 316 L Quality & Food grade silicon. Capacity available from 1 Kg to 25 Kg for laboratory and pilot scale plants. Single Pot Technology for mixing, drying & Agglomerating Inbuilt Inlet Air handler with S.S. Electric heater, 20 & 5 micron filter & 0.3 micron HEPA. Exhaust air blower with 20 micron filter. Option for Interchangeable Bowl 5 kg, 3 Kg, and 1 Kg. Option for advance PLC controls system with HMI Touch screen.
	Safety Features:
	Explosion flap fitted with aluminum material for safety. Auto shutoff system for over limit temperature & when process is completed. Air pressure switch installed to ensure pressure is in limit. Differential pressure indicator for filter bag, Product sieve and HEPA Filter. Safe earthing system for static current & Overload relay controls.

Fluid Bed Dryer

High Precision Fluidize Fast Drying & Agglomerating Process Technic

Application & Process :

Prism Fluid Bed Processing involves fast drying, cooling and agglomeration of particulate materials. It is ideal for heat sensitive and non heat sensitive products in Pharmaceuticals, Chemicals and Biochemical, Food and Dairy Industries.

The Fluid Bed Dryer have a bed of solid particles which are fluidized by passing a stream of air upward through a specially designed perforated sheet. The upward velocity of air is so maintained so as to slightly lift the solid particles and set them in motion. This motion can be utilized to bring about mixing as well as forward movement of the solids particles. The air is heated and the process hot air evaporates the fluid and dries the solids. Fines get agglomerated to larger granules particles thus providing large size

The machine is designed with correct volume of bowl, air velocity, direction and the temperature of the clean inlet air is maintained throughout the fluidization, retarding, and expansion chambers, filtration area, pitch of the perforations of the plate at the bottom of product container, the leak-proof fluidization space by proper sealing, material of the filters and process controls with electrical & pneumatically.

The uniform drying is achieved by exposing the full surface of every particles of the solid mass to the incoming high velocity hot air.

Option for the process parameters are controlled by using latest PLC controls with HMI touch screen thus making equipment operationally safe and eliminating the possibility of human error. The process consistency with batch records is maintained for every batch every time.

The equipment can be inbuilt CIP system gives a thoroughly cleaned equipment for every batch eliminating contamination of subsequent batches.

Salient Features :

• Design is cGMP - Current Good Manufacturing Practices compliance.
• All contact parts AISI 316 & non contact parts AISI 304.
• Single piece construction with Integrated retarding expansion chamber cum filter bag housing
• Batch type dryer with available capacity 30 kg to 500 kg. Batch size
• Pneumatic Sealing of Filter Bag and Product container by inflatable silicon rubber tube.
• Inlet Air handler with Air Filter- Micro, HEPA and Heat Exchanger Steam or Electric.
• Exhaust air blower with dynamic balance fan.
• Built in Explosion vents and isolation valve protect equipment.
• Automatic Temperature controls for Inlet Air and Process cycle time controls.
• Washable filter media, FDA approved.
• Auto pneumatic filter bag shacking system.
• Sampling pot on product container.
• Electric and Pneumatic controls panel.

Optional Features :

• Additional Product container.
• Advance PLC controls with touch screen
• Double scan AHU with Dehumidifier.
• Steam or Electric Heater
• Exhaust AHU with Filter
• Silencer at exhaust blower.
• CIP - WIP system.
• Explosion proof motor and push button.
• Solid flow detection System.
• Differential Pressure gauge for filter.
• Standard model machine with contact parts in S.304 & Non contact parts epoxy painted.

Safety Features :

• Product Bowl interlocking mechanism.
• Automatic Temperature & controls, Process cycle controls.
• Explosion flap ensure at retarding chamber.
• Safe earthling system for static current.
• Air pressure switch installed to ensure pressure is in limit.
• Overload relay Protection and Emergency stop button.

High precision low temperature vacuum Drying & Mixing Process Technology

Application & Process :

The Roto Double Cone Vacuum Dryer is suitable for drying the material which can not operate at low Temperature easily oxidized, poisonous in nature. The Double Cone Rotating Vacuum Drying Equipment is a new drier that integrates mixing and drying in the one body and equips with condenser and vacuum pump. Therefore the vacuum drier is formed. The drier is advanced in design, simple in inner structure, easy for cleaning, to discharge all raw material, convenient in operation and improving work environment. Meanwhile raw material is rotating accompanying with the rotating of container; raw materials cannot be accumulated onto the wall of container, so it has high efficiency heat transfer and high speed drying which save energy. Raw materials are dried uniformly and have good quality at low temperature. It can widely apply to dry raw materials of pharmaceuticals, chemical, Pesticides, foodstuff , dyestuff and so on industries. The equipment is in conformity with the requirements of "GMP". If the solvent does not recover, the condenser may be not used.

• 1. Material that cannot undertake high temperature.
• 2. Material that is easy to oxidize.
• 3. Material that do not permit to destruct.
• 4. To recover material with residual volatile.
• 5. Material with vigorous irritative and toxicity

The Roto Cone Vacuum Drier consists of a jacketed double conical shell rotating around 6 RPM with under the state of vacuum inside the shell, pass steam or hot water in to jacket for heating. The large heating surface area presented by the internals of the cone ensures uniform drying of the product, as the product gently tumbles while the cone rotates slowly. The vaporized steam can be pumped out through vacuum exhaust pipe when the damp raw material absorbed heat. The diffusive action induced by the tumbling cone constantly presents a fresh layer to come into contact with the indirectly heated walls of the shell, the dry speed of raw material is quickened and uniform drying efficiency is raised too. A well designed sealing system enable maintenance of deep vacuum inside the shell, and also ensures positive circulation of a heating media in the jacket.

Salient Features :

• Design is cGMP - Current Good Manufacturing Practices compliance
• All Product contact parts AISI 316/ 316L & non contact parts AISI 304.
• Simple & compact Design for Easy to operate, clean, convenient & user friendly.
• Automated mixing and Drying process in single bowl.
• Dust free operation.
• High vacuum operation
• Low temperature drying.
• Solvent recovery
• Continuous rotation of container, material will make complex impacting motion in the container and reach to uniform mixing and drying at low temperature.
• Continues vacuum maintenance during process.
• Vacuumized closed system with condenser, Receiver for solvent recovery & Cyclone separator to recovery the solid particle.
• Rapid & Complete discharge / Zero holdup after discharge
• The product dried is homogeneous with uniform properties.
• Very low value of final moisture even at low drying temperatures.
• Inside Filter assembly with 5 Micron.

Safety Features :

• Temperature controls, Process controls, Vacuum relief valve, Over load protection and Emergency stop.

Optional Features :

• Option for advance PLC Controls with HMI touch screen.
• Option for Flame Proof Electrical.
• Option for lump breaker.
• Option for condenser, Receiver & Cyclone for solvent recovery.
• Option for heating media steam/ hot water / hot oil.

Vacuum Shelf Tray Dryer

High precision low temperature vacuum Drying & Mixing Process Technology

Application & Process :

The Vacuum Shelf Tray Dryers are used to het and dry material under the state of vacuum is called vacuum drying and where difficulties in drying materials due to high toxic contents, hygroscopic in nature, heat sensitive. It is widely used in the pharmaceutical, Herbal, chemical & foodstuff.

The Vacuum Shelf Dryer is basically a tray dryer working under vacuum conditions. Its use vacuum to pump air and humidity out from the closed heat chamber due to vacuum making the chamber on the vacuum state thus increased drying rate greatly and saved energy. The boiling point of the material to be brought down for drying and the entire system is in closed loops so, no contamination occurs. The evaporation's evolved during the drying process is cooled down through a connected condenser and collected in receiver. The vacuum shelf dryer when combined with solvent extraction system, ensures that almost all of evaporating vapors is recovered and condensed in to a receiver. Vacuum shelf dryer is closed chamber with heavy structure with air lock doors, Jacketed and insulated body. Inside chamber there are shelves for resting tray. Shelves are manufactured in hollow construction with baffles cum stiffeners, inlet and outlet nozzle. Hot media is passed through the Inlet Header to each shelf, so heat transfer to the surface, which in turn heats up trays placed on the shelves. The hot media flows out from the shelves through the Outlet Header.

Salient Features :

• Design is cGMP with product contact parts AISI 316.
• Vacuumize shelves drying on low temperature system for high toxic. Hygroscopic & heat sensitive materials.
• Vacuumize closed system can be with condenser, Receiver for solvent recovery.
• Very low value of final moisture even at low drying temperatures.
• Safety feature: Vacuum relief valve, Safety pressure relief valve, Temperature Controller & Overload protection.
• Option for heating media can be steam/ hot water / hot tharmic fluid.
• Option features: condenser & Receiver for solvent recovery & Evaporation cooling, PLC Controls, Explosion Proof Electrical

Ribbon Vacuum Mixer Dryer

Low Temperature Vacuum Mixing &Drying Process Technik

Application & Process :

The Ribbon Vacuum Mixer Dryer is suitable for mixing and drying the material which can not operate at low Temperature easily oxidized, poisonous in nature. It operates at low Temperature efficiently under vacuum. It is used for raw materials drying and mixing powder or granules of Pharmaceutical Materials, Crystalline, Insecticides, Pesticides, and Food industry and heat sensitive products.

The Ribbon Vacuum Mixer Dryer consists of a jacketed cylindrical shell with rotating with specially designed Double Helical Ribbon Agitator type blade by rigid fabricated structure motor, gear box. There is provision for application of vacuum inside the shell and circulation of heating media in the jacket during the rotation of the stirrer. The large heating surface area presented by the internals of the cylindrical shell ensures uniform drying of the product, as the product gently moving while the ribbon stirrer rotates. The diffusive action induced by the mixing stirrer constantly presents a fresh layer to come into contact with the indirectly heated walls of the shell. A well designed sealing system enable maintenance of deep vacuum inside the shell, and also ensures positive circulation of a heating media in the jacket.

In operation, material is filled to the top of the outer ribbon. The shaft rotates at relatively low speed and the moving ribbons push the material back and forth mixing it. The outer ribbon rotation displaces the material from the ends to the center while the inner ribbon rotations move the material from the center to the ends. This counter-current action results in homogenous blending. Mixing is achieved in 15 to 20 minutes with 90 to 95 % or better homogeneity. The bottom discharge provided for unloading of the material and easy cleaning of the mixing drum. Specially designed self adjusting sealing arrangement of unique design is provided to ensure that no black particle enters into the mixing drum.

Salient Features :

• Design is cGMP- Current Good Manufacturing Practices compliance.
• All contact parts AISI 316 & non contact parts AISI 304.
• Continuous rotation of ribbon blade, material will make continuous movement motion in the container and reach to uniform mixing and drying at low temperature.
• Dust free operation.
• High vacuum operation
• Fast and uniform homogeneous mixing & draying at low temperature.
• Solvent recovery
• Continues vacuum maintain during process.
• Very low value of final moisture even at low drying temperatures.
• Option for two type design of shell 1. Cylindrical type and 2. "U" shape.
• Continues vacuum maintenance during process.
• Vacuumized closed system with condenser, Receiver for solvent recovery & Cyclone separator to recovery the solid particle.
• Rapid & Complete discharge / Zero holdup after discharge
• Heating media can be used steam/ hot water / hot oil.

Optional Features :

• Option for two type designed of shell 1. Cylindrical type and 2."U" shape.
• Option for Flame Proof Electrical.
• Option for Automatic Charging
• Option for lump breaker.
• Option for condenser, Receiver & Cyclone for solvent recovery.
• Option for advance PLC Controls with HMI touch screen.

Safety Features :

• Temperature controls, Vacuum relief Valve, Over load protection and Emergency stop.

Low temperature Vacuumized drying process Technic

Application & Process :

The Vacuum Paddle Mixer Dryer is suitable for mixing and drying the material which can not operate at low Temperature easily oxidized, poisonous in nature. It operates at low Temperature efficiently under vacuum. It is used for raw materials drying and mixing powder or granules of Pharmaceutical Materials, Crystalline, Insecticides, Pesticides, and Food industry and heat sensitive products.

• Material that cannot undertake high temperature.
• Material that is easy to oxidize.
• Material that do not permit to destruct.
• To recover material with residual volatile.
• Material with vigorous irritative and toxicity

The Vacuum Paddle Mixer Dryer consists of a jacketed cylindrical shell with rotating with specially designed Paddle Agitator type blade by rigid fabricated structure motor, gear box. There is provision for application of vacuumized inside the shell and circulation of heating media in the jacket during the rotation of the stirrer. The large heating surface area presented by the internals surface of the shell ensures uniform drying of the product, as the product gently moving & fluidized while the Paddle stirrer rotates. The diffusive action induced by the mixing stirrer constantly presents a fresh layer to come into contact with the indirectly heated walls of the shell. A well designed sealing system enable maintenance of deep vacuum inside the shell, and also ensures positive circulation of a heating media in the jacket.

In operation, material is filled to the top of the shell. The shaft rotates at relatively low speed and the moving paddles push and fluidized the material back and forth mixing it. The outer Paddle rotation displaces the material from the ends to the center while the inner paddle rotations move the material from the center to the ends. This counter-current action results in homogenous blending. Mixing is achieved in 15 to 20 minutes with 90 to 95 % or better homogeneity. The bottom discharge provided for unloading of the material and easy cleaning of the mixing drum. Specially designed self adjusting sealing arrangement of unique design is provided to ensure that no black particle enters into the mixing drum.

Salient Features :

• Design is cGMP- Current Good Manufacturing Practices compliance.
• All contact parts AISI 316 & non contact parts AISI 304.
• Continuous rotation of paddle stirrer, material will make continuous movement and fluidized in the container and reach to uniform mixing and drying at low temperature.
• Dust free operation.
• High vacuum operation
• Fast and uniform homogeneous mixing & draying at low temperature.
• Solvent recovery
• Continues vacuum maintain during process.
• Very low value of final moisture even at low drying temperatures.
• Option for two type design of shell 1. Cylindrical type and 2. "U" shape.
• Continues vacuum maintenance during process.
• Vacuumized closed system with condenser, Receiver for solvent recovery & Cyclone separator to recovery the solid particle.
• Rapid & Complete discharge / Zero holdup after discharge
• Heating media can be used steam/ hot water / hot oil.
• Rigid drive with reduction gear box, motor and stuffing box for shaft sealing.
• Charging pot, Vacuum connection, , sight glasses, Vacuum relief valve & gauge are provided on top of the shell.
• Connection at jacket will be provided for steam Inlet, safety valve, Pressure gauge and steam trap.
• The discharge with butterfly valve/Slide valve at bottom side of the shell

Optional Features :

• Option for two type designed of shell 1. Cylindrical type and 2."U" shape.
• Option for Flame Proof Electrical.
• Option for Automatic Charging
• Option for lump breaker.
• Option for condenser, Receiver & Cyclone for solvent recovery.
• Option for advance PLC Controls with HMI touch screen.

Design is cGMP with product contact parts AISI 316.Vacuumize shelves drying on low temperature system for high toxic. Hygroscopic & heat sensitive materials.Vacuumize closed system can be with condenser, Receiver for solvent recovery.Very low value of final moisture even at low drying temperatures.Safety feature: Vacuum relief valve, Safety pressure relief valve, Temperature Controller & Overload protection.Option for heating media can be steam hot water hot tharmic fluid.Option features: condenser & Receiver for solvent recovery & Evaporation cooling, PLC Controls, Explosion Proof Electrical

Available in 24, 48, 96 & 192 Trays.Design is cGMP Current Good Manufacturing Practices compliance.All contact parts AISI 316304 & non contact parts AISI 304 M.S. with painted.Highly effective uniform air re-circulating system by low speed fan.Inlet air filter and damper at inlet and exhaust air damper for air flow controls.Controls panel with Digital temperature controller and process timer controller.Mobile trolleys are provided which are used to load and unload the trays into the dryer.

High speed mixing & granulatingDesign is cGMP Current Good Manufacturing Practices complianceAll Product contact parts AISI 316 & non contact parts AISI 304.Automated maxing and granulating process in single bowl.High Precision mixing and granulation with Short Batch Time, Problem free Cleaning and Residue Free Discharge.Unique design with four arm mixing impeller with blade angle to pushing product radically outward.Chopper blade designed to cuts lumps and make granules.Dual speed mixing impeller for mixing and intensify chopper for granulating.Flush fitting discharge plug is electro pneumatically operated.Air pursing for seal for both shafts.

Design is cGMP Current Good Manufacturing Practices complianceAll Product contact parts AISI 316 316L & non contact parts AISI 304.Simple & compact Design for Easy to operate, clean, convenient & user friendly.Automated mixing and Drying process in single bowl.Dust free operation.High vacuum operationLow temperature drying.Solvent recoveryContinuous rotation of container, material will make complex impacting motion in the container and reach to uniform mixing and drying at low temperature.Continues vacuum maintenance during process.Vacuumized closed system with condenser, Receiver for solvent recovery & Cyclone separator to recovery the solid particle.Rapid & Complete discharge Zero holdup after dischargeThe product dried is homogeneous with uniform properties.Very low value of final moisture even at low drying temperatures.Inside Filter assembly with 5 Micron

Fluid Bed Dryer

High Precision Fluidize Fast Drying & Agglomerating Process Technic

Application & Process :

PrismFluid BedProcessing involves fast drying, cooling and agglomeration of particulate materials. It is ideal for heat sensitive and non heat sensitive products in Pharmaceuticals, Chemicals and Biochemical, Food and Dairy Industries.

TheFluid Bed Dryerhave a bed of solid particles which are fluidized by passing a stream of air upward through a specially designed perforated sheet. The upward velocity of air is so maintained so as to slightly lift the solid particles and set them in motion. This motion can be utilized to bring about mixing as well as forward movement of the solids particles. The air is heated and the process hot air evaporates the fluid and dries the solids. Fines get agglomerated to larger granules particles thus providing large size

The machine is designed with correct volume of bowl, air velocity, direction and the temperature of the clean inlet air is maintained throughout the fluidization, retarding, and expansion chambers, filtration area, pitch of the perforations of the plate at the bottom of product container, the leak-proof fluidization space by proper sealing, material of the filters and process controls with electrical & pneumatically.

The uniform drying is achieved by exposing the full surface of every particles of the solid mass to the incoming high velocity hot air.

Option for the process parameters are controlled by using latest PLC controls with HMI touch screen thus making equipment operationally safe and eliminating the possibility of human error. The process consistency with batch records is maintained for every batch every time.

The equipment can be inbuilt CIP system gives a thoroughly cleaned equipment for every batch eliminating contamination of subsequent batches.

Salient Features :

• Design is cGMP - Current Good Manufacturing Practices compliance.
• All contact parts AISI 316 & non contact parts AISI 304.
• Single piece construction with Integrated retarding expansion chamber cum filter bag housing
• Batch type dryer with available capacity 30 kg to 500 kg. Batch size
• Pneumatic Sealing of Filter Bag and Product container by inflatable silicon rubber tube.
• Inlet Air handler with Air Filter- Micro, HEPA and Heat Exchanger Steam or Electric.
• Exhaust air blower with dynamic balance fan.
• Built in Explosion vents and isolation valve protect equipment.
• Automatic Temperature controls for Inlet Air and Process cycle time controls.
• Washable filter media, FDA approved.
• Auto pneumatic filter bag shacking system.
• Sampling pot on product container.
• Electric and Pneumatic controls panel.

High Effective Hot Air Re-circulation - Tray Drying Technic

Application & Process :

Tray Drying Ovens are used for drying of pharmaceutical powders, granules, Pigments, Food, Bakery, Electrodes, Chemical, and Plastic etc in an effective and economical way by hot air re-circulation.

Tray dryer is an enclosed insulated chamber in which trays are placed on top of each other. Heat transfer is done by circulation of hot air by electric heaters or any other heating media. Blower fans are installed inside to ensure proper circulation and transfer of heat.

Salient Features :

• Available in 24, 48, 96 & 192 Trays.
• Design is cGMP - Current Good Manufacturing Practices compliance.
• All contact parts AISI 316/304 & non contact parts AISI 304/ M.S. with painted.
• Highly effective uniform air re-circulating system by low speed fan.
• Inlet air filter and damper at inlet and exhaust air damper for air flow controls.
• Controls panel with Digital temperature controller and process timer controller.
• Mobile trolleys are provided which are used to load and unload the trays into the dryer.

Tray Dryer

High Effective Hot Air Re-circulation - Tray Drying Technic

Application & Process :

Tray Drying Ovens are used for drying of pharmaceutical powders, granules, Pigments, Food, Bakery, Electrodes, Chemical, and Plastic etc in an effective and economical way by hot air re-circulation.

Tray dryer is an enclosed insulated chamber in which trays are placed on top of each other. Heat transfer is done by circulation of hot air by electric heaters or any other heating media. Blower fans are installed inside to ensure proper circulation and transfer of heat.

Salient Features :

• Available in 24, 48, 96 & 192 Trays.
• Design is cGMP - Current Good Manufacturing Practices compliance.
• All contact parts AISI 316/304 & non contact parts AISI 304/ M.S. with painted.
• Highly effective uniform air re-circulating system by low speed fan.
• Inlet air filter and damper at inlet and exhaust air damper for air flow controls.
• Controls panel with Digital temperature controller and process timer controller.
• Mobile trolleys are provided which are used to load and unload the trays into the dryer.

The Fluid Bed Dryer have a bed of solid particles which are fluidized by passing a stream of air upward through a specially designed perforated sheet. The upward velocity of air is so maintained so as to slightly lift the solid particles and set them in motion. This motion can be utilized to bring about mixing as well as forward movement of the solids particles. The air is heated and the process hot air evaporates the fluid and dries the solids. Fines get agglomerated to larger granules particles thus providing large size. The machine is designed with correct volume of bowl, air velocity, direction and the temperature of the clean inlet air is maintained throughout the fluidization, retarding, and expansion chambers, filtration area, pitch of the perforations of the plate at the bottom of product container, the leak-proof fluidization space by proper sealing, material of the filters and process controls with electrical & pneumatically.