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Supplied By
UMA Brothers, India
We are offering zonisamide.Zonisamide is an anti-epileptic agent. The mechanism action of zonisamide is as a carbonic anhydrase inhibitor & p-glycoprotein inhibitor. The physiologic effect ofzonisamide is by means of decreased central nervous system disorganized electrical activity. The chemical classi- fication of zonisamide is sulfonamides. Zonisamide is a sulfonamide derivative with an anticonvulsant property the exact mechanism of action remains to be elucidated. zonisamide appears to block sodium & calciumchannels, thereby stabilizing neuronal membranes and suppressing neuronal hyper-synchronization. Although zonisamide shows affinity for the gamma-aminobutyric acid (gaba)benzodiazepine receptor ionophore complex, it does not potentiate the synaptic activity of gaba. In addition, this agent also facilitates both dopaminergic and serotonergic neurotransmission. synonyms: (1, 2-benzoxazol-3-ylmethanesulfonamidecas number: 68291-97-4, mol. Formula: c8h8n2o3s, mol.weight: 212.23zonisamide is an off-white solid powder. It is soluble in water (10 mm), dmso (100 mm), 1.1eq naoh (100 mm), ethanol (25 mm), methanol, and ethyl acetate with melting range of 162c to 167c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements