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Supplied By
UMA Brothers, India
We are offering pamidronate disodium is the disodium salt of the synthetic bisphospho- nate pamidronate. Although its mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation.Pamidronate disodium salt is a bisphosphonate compound, which inhibits farnesyl diphosphate synthase & bone resorption. Studies suggest that pamidronate disodium salt stimulates polymorphonuclear leukocyte and platelet derived nitric oxide production. It is believed that this nitric oxide production can lead to a negative feedback mechanism, which could restrict the inflammatory process and reduce bone resorption. Furthermore, bisphosphonates induce endothelial cell death, cancer cell apoptosis, and nuclear factor-b pathway activation, via the endothelial protein c receptor. synonyms: disodium; [3-amino-1-hydroxy-1-[hydroxy (oxido) phosphoryl] propyl] hydroxyphosphinate; pentahydratecas number: 57248-88-1, mol. Formula: c3h9nna2o7p2.xh2o, mol.weight: 279.03pamidronate disodium is white crystalline powder. It is soluble in water: 28 mgml with melting point of 300c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements
GST : 27AGPPS8689E1ZF
4.7/5
Ashok Shah (Uma Brothers)
C-110, Bhaveshwar Plaza, 189, Lbs Marg, Ghatkopar West., Mumbai, Maharashtra - 400086, India
https://www.umabrothers.in
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