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Pharmaceuticals Tablets

We offer the best product range of Nateglinide, Gefitinib, DOCETAXEL, flunarizine dihydrochloride and Etamsylate.

Nateglinide

  • Supplied By UMA Brothers, India

We are offering nateglinide. Nateglinide is a glinide. The mechanism of action of nateglinide is as a potassium channel antagonist. Nateglinide is a phenylalanine derivative of the meglitinide class of agents with hypoglycemic activity. Nateglinide compared to repaglitinide binds with a higher affinity to the sur1 subunit and with a faster onset of action and a shorter duration of action. This agent is metabolized by the cytochrome p450 isoenzyme cyp2c9, and, to a lesser extent, by cyp3a4. The parent drug and metabolites are mainly excreted in the urine and its half-life is about 1.5 hours. synonyms: (2r)-3-phenyl-2-[(4-propan-2-ylcyclohexanecarbonyl) amino] propanoic acid cas number: 105816-04-4, mol. Formula: c19h27no3, mol.weight: 317.42 nateglinide is a crystal solid powder. It is soluble in water practically insoluble with melting range of 137°c to 141°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Gefitinib

  • Supplied By UMA Brothers, India

We are offering gefitinib is a kinase inhibitor. The mechanism of action of gefitinib is as a protein kinase inhibitor. Gefitinib is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by astrazeneca under the trade name iressa. synonyms: n-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy) quinazolin-4-amine cas number: 184475-35-2, mol. Formula: c22h24clfn4o3, mol.weight: 446.9 gefitinib is a light-yellow crystalline powder. It is soluble in dmso (89 mgml at 25 °c), methanol (20 mgml), ethanol (4 mgml at 25 °c), dmf (20 mgml), and water (

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Docetaxel

  • Supplied By UMA Brothers, India

We are offering docetaxel tablets. Docetaxel anhydrous is a microtubule inhibitor. The physiologic effect of docetaxel anhydrous is by means of microtubule inhibition. Docetaxel anhydrous is the anhydrous form of docetaxel, a semisynthetic side-chain analogue of paclitaxel with antineoplastic property. Docetaxel binds specifically to the beta-tubulin subunit of microtubules and thereby antagonizes the disassembly of the microtubule proteins. This results in the persistence of aberrant microtubule structures and results in cell-cycle arrest and subsequent cell death. synonyms: taxotere;n-debenzoyl-n-tert-butoxycarbonyl-10-deacetyl taxol;)benz(1, 2-b)oxet-9-ylester, (2ar-(2a-alpha, 4-beta, 4a-beta, 6-beta, 9-alpha(alph cas number: 114977-28-5, mol. Formula: c43h53no14, mol.weight: 807.88 docetaxel is off-white crystlline. It is soluble in chloroform, dichloro- methane, dmso, ethyl acetate, methanol, and ethanol (25 mgml) (unlabeled). Insoluble in water (unlabeled) with melting range of 186°c to 192°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Flunarizine Dihydrochloride

  • Supplied By UMA Brothers, India

We are offering flunarizine dihydrochloride. Flunarizine dihydrochloride is a drug classified as a calcium channel blocker. Flunarizine is a non-selective calcium entry blocker with other actions including histamine h1 receptor blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. It may help to reduce the severity and duration of attacks of paralysis associated with the more serious form of alternating hemiplegia, as well as being effective in rapid onset dystonia-parkinsonism (rdp). synonyms: 1-[bis (4-fluorophenyl) methyl]-4-[(e)-3-phenylprop-2-enyl] piperazine; dihydrochloride cas number: 30484-77-6, mol. Formula: c26h28cl2f2n2, mol.weight: 477.42 flunarizine dihydrochloride is white solid powder. It is soluble in dmso (25mgml), 100% ehanol (5mgml) or chloroform: methanol (1:1; 50mgml) with melting range of 188°c to 190°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Etamsylate

  • Supplied By UMA Brothers, India

We are offering ethamsylate is a haemostatic drug benzenesulfonate derivative used as a systemic hemostatic. It is believed to work by increasing capillary endothelial resistance and promoting platelet adhesion. It also inhibits biosynthesis and action of those prostaglandins which cause platelet disaggregation, vasodilation and increased capillary permeability. synonyms: 2, 5-dihydroxybenzenesulfonic acid; n-ethylethanamine cas number: 2624-44-4, mol. Formula: c10h17no5s, mol.weight: 263.31 ethamsylate is a white solid powder. It is easily soluble in water, soluble in ethanol, slightly soluble in acetone, insoluble in chloroform and ether with melting range of 127°c to 131°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Zidovudine

  • Supplied By UMA Brothers, India

We are offering zidovudine is a dideoxynucleoside compound in which the 3'-hydroxy group on sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of hiv replication acting as a chain-terminator of viral dna during reverse transcription. It improves immunologic function partially reverses the hiv-induced neurological dysfunction, &improves certain other clinical abnormalities associated with aids. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. Zidovudine is a human immunodeficiency virus nucleoside analog reverse transcriptase inhibitor. The mechanism of action of zidovudine is as nucleoside reverse transcriptase inhibitor. The chemical classification of zidovudine is nucleoside analog. Zidovudine is a synthetic dideoxy- nucleoside. After intracellular phosphorylation to its active meta- bolite, zidovudine inhibits dna polymerase, resulting in the inhibition of dna replication & cell death. This agent also decreases levels of available pyrimidines. synonyms: 1-[(2r, 4s, 5s)-4-azido-5-(hydroxymethyl) oxolan-2-yl]-5-methylpyrimidine-2, 4-dione cas number: 30516-87-1, mol. Formula: c10h13n5o5, mol.weight: 283.24 zidovudine is an off-white crystalline powder. It is soluble in water (50 mgml), dmso, and methanol with melting range of 113°c to 115°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Felodipine

  • Supplied By UMA Brothers, India

We are offering felodipine felodipine is a dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. Felodipine is a dihydropyridine calcium channel blocking agent. felodipine inhibits the influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump p-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. synonyms: 5-o-ethyl 3-o-methyl 4-(2, 3-dichlorophenyl)-2, 6-dimethyl-1, 4-dihydropyridine-3, 5-dicarboxylate cas number: 72509-76-3, mol. Formula: c18h19cl2no4, mol.weight: 384.25 felodipine is white or light yellow crystalline powder. It is soluble in dmso (>25 mgml), ethanol (20 mgml), methanol, chloroform, and acetone insoluble in water with melting point of 145°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Metronidazole

  • Supplied By UMA Brothers, India

We are offering metronidazole. Metronidazole is a nitroimidazole used to treat amebiasis; vaginitis; trichomonas infections; giardiasis; anaerobic bacteria &treponemal infections. It has also been proposed as a radiation sensitizer for hypoxic cells according to the fourth annual report on carcinogens. This substance may reasonably be anticipated to be a carcinogen. Metronidazole is a nitroimidazole antimicrobial. The chemical classification of metronidazole is nitroimidazoles. Metronidazole is a synthetic nitroimidazole derivative with antipro- tozoal & antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazoleis readily taken up by obligate anaerobic organisms & is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product reduced metronidazole causes dna strand breaks, thereby inhibiting dna synthesis and bacterial cell growth. Synonyms: 2-(2-methyl-5-nitroimidazol-1-yl) ethanol cas number: 443-48-1, mol. Formula: c6h9n3o3, mol.weight: 171.15 metronidazole is a white to slightly yellow crystalline powder. It is soluble in water (10 mgml at 20 °c), ethanol (5 mgml), methanol, chloroform (

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