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Prilocaine is a local anesthetic of the amino amide type. It is often used in dentistry. It is also often combined with lidocaine as topical preparation for dermal anesthesia, for treatment of conditions like paresthesia.
It works by blocking nerve signals in the body and used as local anesthetics. This is also used for smaller surgery.
Prilocaine binds to the intracellular surface of sodium channels which blocks the subsequent influx of sodium into the cell. This block is reversible and when the drug diffuses away from the cell, sodium channel function is restored and nerve propagation returns.
Prilocaine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation.
The antiarrhythmic actions are mediated through effects on sodium channels in purkinje fibers.
It Is White Crystalline Powder With Purity More Than 99% And Insoluble In Water And Very Soluble In Acetone & Ethanol (96%).
Empagliflozin is new molecule to fight type 2 diabetes. It is good inhibitor of sodium-glucose co-transporter 2 (sglt2; slc5a2) with antihyper glycemic activity. It improves glycemic control in adults with type 2 diabetes mellitus. It is formulated as coated tablets and film-coated tablets for oral route of administration.
Empagliflozin is a sodium-dependent glucose transporter-2 inhibitor (sglt-2 inhibitor). The drug candidate leads to reductions in hepatic glucose production and amelioration of glucotoxicity.
It Is White Colour Powder With Purity More Than 99% And Have Boiling Point 665 C Degree And Flash Point Is 356 C Degree.
