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Pharmaceutical Chemical

Our product range comtains a wide range of Prilocaine, Tazarotene, Secnidazole, Nimodipine and vinpocetine

Prilocaine

  • CAS No. 721-50-6
  • Formula C13H20N2O
  • Molar mass 220.311 G/MOL
  • Supplied By UMA Brothers, India
  • Iupac Name N-(2-methylphenyl)-2-(propylamino)
  • Standard Offered as per in Bp/ep Specifications
  • Packing Offered in Export Worthy Packing with Dry Ice & Ice Gel or as per Our Customer Requirements

Prilocaine is a local anesthetic of the amino amide type. It is often used in dentistry. It is also often combined with lidocaine as topical preparation for dermal anesthesia, for treatment of conditions like paresthesia. It works by blocking nerve signals in the body and used as local anesthetics. This is also used for smaller surgery. Prilocaine binds to the intracellular surface of sodium channels which blocks the subsequent influx of sodium into the cell. This block is reversible and when the drug diffuses away from the cell, sodium channel function is restored and nerve propagation returns. Prilocaine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in purkinje fibers. It Is White Crystalline Powder With Purity More Than 99% And Insoluble In Water And Very Soluble In Acetone & Ethanol (96%).

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Tazarotene

  • Supplied By UMA Brothers, India

We are offering tazarotene. Tazarotene is a retinoid. The chemical classification of tazarotene is retinoids. Tazarotene is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (tig3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. synonyms: ethyl 6-[2-(4, 4-dimethyl-2, 3-dihydrothiochromen-6-yl) ethynyl] pyridine-3-carboxylate cas number: 118292-40-3, mol. Formula: c21h21no2s, mol.weight: 351.46 tazarotene is a soluble in water (partly), chloroform, dmso (>15 mgml), methanol, and ethanol (50 mm) with melting range of 97°c to 98°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Secnidazole

  • Supplied By UMA Brothers, India

We are offering secnidazole. Secnidazole is an anti-ametic, anti-protozoal, and is a nitroimidazole anti-infective analog of metronidazole. Secnidazole is structurally related to the commonly used 5-nitroimidazoles metronidazole and tinidazole. synonyms: 1-(2-methyl-5-nitroimidazol-1-yl) propan-2-ol cas number: 3366-95-8, mol. Formula: c7h11n3o3, mol.weight: 185.18 secnidazole is a crystalline solid. It is soluble in chloroform with melting range of 70°c tp 78°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Nimodipine

  • Supplied By UMA Brothers, India

We are offering nimodipine. Nimodipine is a calcium channel blockader with preferential cerebro vascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure. Nimodipine is a 1, 4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated l-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction & subsequent vasoconstriction. compared to other calcium channel blocking agents, nimodipine exhibits greater effects on cerebral circulation than on peripheral circulation. nimodipine is used to as an adjunct to improve the neurologic outcome following subarachnoid hemorrhage from ruptured intracranial aneurysm. synonyms: 3-o-(2-methoxyethyl) 5-o-propan-2-yl 2, 6-dimethyl-4-(3-nitro phenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate cas number: 66085-59-4, mol. Formula: c21h26n2o7, mol.weight: 418.44 nimodipine is white crystalline powder. It is soluble in methanol (62.5 mgml), dmso (25 mgml), dioxane, water (24.3 mgl) at 25 °c, and ethanol (10 mm) insoluble in 2-hydroxypropyl-b-cyclodextrin with melting point of 125°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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diltiazem

  • Supplied By UMA Brothers, India

We are offering diltiazem. Diltiazem hydrochloride is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of calcium ion on membrane functions. diltiazem hydrochloride is a benzothiazepine calcium channel blocking agent. Diltiazem hydrochloride inhibits the transmembrane influx of extracellular calcium ions into select myocardial and vascular smooth muscle cells, causing dilatation of coronary and systemic arteries and decreasing myocardial contractility. Because of its vasodilatory activity, this agent has been shown to improve the microcirculation in some tumors, thereby potentially improving the delivery of antineoplastic agents to tumor cells. synonyms: [(2s, 3s)-5-[2-(dimethylamino) ethyl]-2-(4-methoxyphenyl)-4-oxo-2, 3-dihydro-1, 5-benzothiazepin-3-yl] acetate; hydrochloride cas number: 42399-41-7, mol. Formula: c22h26n2o4s, mol.weight: 414.52 diltiazem is orange solid powder. It is soluble in water, methanol, and chloroform with melting point of 212°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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vinpocetine

  • Supplied By UMA Brothers, India

We are offering vinpocetine. Vinpocetine is a synthetic derivative of the minor vincarmine from the vinca genus of plants. This compound is a cyclic nucleotide pde (ca2+-dependedcalmodulin-stimulated phosphodiesterase) inhibitor. Studies suggest that vinpocetine’s selective inhibition of pde1 may induce vascular relaxation by increasing cyclic gmp contents in vascular smooth muscle. synonyms: 3a, 16a-apovincaminic acid ethyl ester;(3a, 16a)-eburnamenine-14-carboxylic acid ethyl ester;cavinton;ethyl apovincamin-22-oate;eburnamenine;eburnamenine-14-carboxylic acid ethyl ester;rgh-4405;vinpocetin cas number: 42971-09-5, mol. Formula: c22h26n2o2, mol.weight: 350.45 vinpocetine is a white crystalline solid. It is soluble in dmso (5 mgml), dmf (with warming) (3 mgml), ethanol (50 mm), acetic acid, acetone (25 mgml), and chloroform insoluble in water with melting range of 147°c to 149°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Selegiline Hydrochloride

  • Supplied By UMA Brothers, India

We are offering selegiline hydrochloride. Selegiline hydrochloride is a selective, irreversible inhibitor of type b monoamine oxidase. It is used in newly diagnosed patients with parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. Selegiline hydrochloride is the hydrochloride salt form of selegiline, a levorotatory acetylenic derivative of phenethylamine with antiparkin sonian effect. As a selective monoamine oxidase (mao) inhibitor, selegiline has the greatest affinity for type b mao, found mainly in the brain. selegiline is converted by mao b to an active moiety, which binds irreversibly at the active site of the enzyme's cofactor fad (flavin adenine dinucleotide) molecule. This prevents the oxidative deamination of catecholamines and serotonin by mao b, and leads to an increase in these neurotransmitters' activities resulting in improved motor function. In addition, this agent may inhibit re-uptake of dopamine by the neuron and prolongdopamine activity. synonyms: (2r)-n-methyl-1-phenyl-n-prop-2-ynylpropan-2-amine; hydrochloride cas number: 14611-52-0, mol. Formula: c13h18cln, mol.weight: 223.74 selegiline is a crystalline solid. It is soluble in water (25 mgml), chloroform, ethanol, and methanol with melting range of 141.5°c tp 142.5°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Ketoprofen

  • Supplied By UMA Brothers, India

We are offering ketoprofen. Ketoprofen is an ibuprofen-type anti-inflammatory analgesic and antipyretic. It is used in the treatment of rheumatoid arthritis and osteoarthritis. Ketoprofen is a propionic acid derivate and nonsteroidal antiinflam matory drug (nsaid) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I & ii, resulting in a decreased formation of precursors of prostaglan- dins & thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane a2 synthesis, by thromboxanesynthase, thereby inhibiting platelet aggregation. synonyms: 2-(3-benzoylphenyl) propanoic acid cas number: 22071-15-4, mol. Formula: c16h14o3, mol.weight: 254.28 ketoprofen is a white crystalline solid powder. It is soluble in ethanol (51 mgml at 25 °c), dmso (51 mgml at 25 °c), water (

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Oxymetazoline Hydrochloride

  • Supplied By UMA Brothers, India

We are offering oxymetazoline hydrochloride is a direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (from martindale, the extra pharmacopoeia, 30th ed, and p1251) oxymetazoline hydrochloride is the hydrochloride salt form of oxymetazoline, an imidazole derivative with a direct acting sympathomimetic property. Oxymetazoline binds to and activates alpha-2 adrenergic receptors. Upon nasal or ocular administration, oxymetazoline constricts the arterioles in the nose and eye, resulting in decreased nasal and conjunctival congestion, respectively. Since vascular beds widely express α1 receptors, the action of oxymetazoline results in vasoconstriction due to its action on endothelial α2 receptors. Oxymetazoline hydrochloride is an inhibitor of sr-2c and an activator of sr-1a, sr-1b, sr-1d and sr-2c. synonyms: 6-tert-butyl-3-(4, 5-dihydro-1h-imidazol-2-ylmethyl)-2, 4-dimethylphenol; hydrochloride cas number: 2315-02-8, mol. Formula: c16h25cln2o, mol.weight: 296.84 oxymetazoline hydrochloride is off-white solid powder. It is soluble in water (50 mgml), alcohol (1: 3.6), methanol, dmso (59 mgml), and ethanol (59 mgml) with melting range of 300°c to 303°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Empagliflozin

  • Formula C23H27CLO8
  • CAS No 864070-44-0
  • Molecular Weight 466.91
  • Iupac Name 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy) Benzyl) Benzene
  • Standard Offered as per in House Specifications
  • Packing Offered in Export Worthy Packing or as per Our Customer Requirements
  • Supplied By UMA Brothers, India

Empagliflozin is new molecule to fight type 2 diabetes. It is good inhibitor of sodium-glucose co-transporter 2 (sglt2; slc5a2) with antihyper glycemic activity. It improves glycemic control in adults with type 2 diabetes mellitus.   It is formulated as coated tablets and film-coated tablets for oral route of administration. Empagliflozin is a sodium-dependent glucose transporter-2 inhibitor (sglt-2 inhibitor). The drug candidate leads to reductions in hepatic glucose production and amelioration of glucotoxicity. It Is White Colour Powder With Purity More Than 99% And Have Boiling Point 665 C Degree And Flash Point Is 356 C Degree.

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  • Ashok Shah
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