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  58. Other Products 28 Products available

Medicines Tonics and Drugs

We offer a complete product range of Glimepiride, Linagliptin, Carvedilol, Celecoxib and Ketoconazole

GLIMEPIRIDE

  • Supplied By UMA Brothers, India

SYNONYMS: 1-(4-(2-(3-ETHYL-4-METHYL-2-OXO-3- PYRROLINE CARBOXAMIDO) ETHYL) PHENYLSULFONYL)-3-(4-METHYLCYCLOHEXYL) UREA CAS NUMBER: 93479-97-1 , MOLECULAR FORMULA: C24H34N4O5S, MOLECULAR WEIGHT: 490.62 IT IS A WHITE CYRSTALLINE SOLID WITH MELTING RANGE OF 212.2° C TO 214.5° C. IT IS INSOLUBLE IN WATER. STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP   PACKING: OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

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LINAGLIPTIN

  • Supplied By UMA Brothers, India

SYNYNOMS:  1H- PURINE -2, 6-DIONE, 8-[(3R)-3-AMINO-1-PIPERIDINYL]-7-(2-BUTYN-1-YL)-3, 7-DIHYDRO-3-METHYL-1-[(4-METHYL-2QUINAZOLINYL) METHYL]   CAS NUMBER: 668270-12-0 MOLECULAR FORMULA:  C25H28N8O2 AND THE MOLECULAR WEIGHT IS 472.54 G/MOL. LINAGLIPTIN IS A WHITE TO YELLOWISH, NOT OR ONLY SLIGHTLY HYGROSCOPIC SOLID SUBSTANCE. IT IS VERY SLIGHTLY SOLUBLE IN WATER (0.9 MG/ML). IT HAS MELTING POINT 202 °C   STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP   PACKING: OFFERED IN EXPORT WORTHY PACKING OF 5 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

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CARVEDILOL

  • Supplied By UMA Brothers, India

SYNONYMS: 1-(9H-CARBAZOL-4-YLOXY)-3-[2-(2-METHOXY PHENOXY) ETHYLAMINO] PROPAN-2-OL CAS NUMBER: 72956-09-3, MOL FORMULA: C24H26N2O4, MOL. WEIGHT: 406.5 IT IS A WHITE TO OFF-WHITE POWDER WITH ITS MELTING RANGE OF 113 °C- 117 °C. IT IS FREELY SOLUBLE IN DIMETHYLSULFOXIDE; SOLUBLE IN METHYLENE CHLORIDE AND METHANOL; SPARINGLY SOLUBLE IN 95% ETHANOL AND ISOPROPANOL; SLIGHTLY SOLUBLE IN ETHYL ETHER; AND PRACTICALLY INSOLUBLE IN WATER. STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP   PACKING: OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

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CELECOXIB

  • Supplied By UMA Brothers, India

SYNONYMS: 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL) PYRAZOL-1-YL] BENZENESULFONAMIDE CAS NUMBER: 169590-42-5, MOL. FORMULA: C17H14F3N3O2S. MOL. WEIGHT: 381.37.   IT IS YELLOW CRYSTALLINE POWDER, SOLUBLE TO 25 MM IN DMSO AND TO 50 MM IN ETHANOL AND VERY LOW  WATER SOLUBILITY WITH ITS MELTING POINT OF 157 °C TO 158 °C

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KETOCONAZOLE

  • Supplied By UMA Brothers, India

SYNONYMS: 1-[4-[4-[[(2R, 4S)-2-(2, 4-DICHLOROPHENYL)-2-(IMIDAZOL-1-YLMETHYL)-1, 3-DIOXOLAN-4-YL] METHOXY] PHENYL]PIPERAZIN-1-YL] ETHANONE CAS NUMBER: 65277-42-1, MOLECULAR FORMULA: C26H28Cl2N4O4, MOLECULAR WEIGHT: 531.43092 G/MOL. IT IS WHITE COLOUR CRYSTALS OR POWDER WITH ITS MELTING RANGE OF 146°C TO 152°C. IT IS SOLUBLE IN WATER. STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP     PACKING: OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

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BENZOCAINE POWDER

  • Supplied By UMA Brothers, India

SYNONYMS: ETHYL 4-AMINOBENZOATE - CAS NUMBER: 94-09-7, MOL. FORMULA: C9H11NO2, MOL.WEIGHT: 165.18 IT IS WHITE OR ALMOST WHITE ODOURLESS CRYSTALLINE POWDER IT IS SOLUBLE IN ACID WITH MELTING POINT OF 92°C STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP   PACKING: OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

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ATORVASTATIN CALCIUM

  • Supplied By UMA Brothers, India

SYNONYMS: CALCIUM, (3R, 5R)-7-[2-(4-FLUOROPHENYL)-3-PHENYL-4-(PHENYL CARBAMOYL)-5-PROPAN-2-YLPYRROL-1-YL]-3, 5-DIHYDROXYHEPTANOATE   CAS NUMBER: 134523-03-8, MOL. FORMULA: C66H68CAF2N4O10, MOL.WEIGHT: 1155.36   IT IS A WHITE TO OFF WHITE CRYSTALLINE POWDER, INSOLUBLE IN AQUEOUS SOLUTIONS OF PH 4 AND BELOW. ATORVASTATIN CALCIUM IS VERY SLIGHTLY SOLUBLE IN DISTILLED WATER, PH 7.4 PHOSPHATE BUFFER, AND ACETONITRILE; SLIGHTLY SOLUBLE IN ETHANOL AND FREELY SOLUBLE IN METHANOL WITH ITS MELTING RANGE OF 176°C TO 178°C.   STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP   PACKING: OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS

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FLUTICASONE PROPIONATE

  • Supplied By UMA Brothers, India

SYNONYMS: FLUTICASONE, CAS NO: 80474-14-2, MOLECULAR WEIGHT: 500.6, MOLECULAR FORMULA: C25H31F3O5S  IT IS A WHITE POWDER, PRACTICALLY INSOLUBLE IN WATER, FREELY SOLUBLE IN DIMETHYL SULFOXIDE AND DIMETHYLFORMAMIDE, AND SLIGHTLY SOLUBLE IN METHANOL AND 95% ETHANOL WITH MELTING RANGE 272 °C TO 273 °C STANDARD: OFFERED OF PHARMACEUTICAL GRADE BP/USP/EP   PACKING: OFFERED IN EXPORT WORTHY PACKING OR AS PER OUR CUSTOMER REQUIREMENTS

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Quetiapine

  • Synonyms 2-[2-(4-BENZO [B] [1, 4] Benzothiazepin-6-Ylpiperazin-1-YL) Ethoxy] Ethanol
  • Cas Number 111974-69-7
  • Mol. Formula C21H25N3O2S
  • Mol.weight 383.51
  • Standard Offered of Pharmaceutical Grade BP/USP/EP
  • Packing Offered in Export Worthy Packing or as per Our Customer Requirements
  • Supplied By UMA Brothers, India

Quetiapine is a dibenzothiazepine and antipsychotic agent that targets the serotonin 5-ht2 receptor; histamine h1 receptor, adrenergic alpha1 and alpha2 receptors, as well as the dopamine d1 receptor and dopamine d2 receptor. It is used in the treatment of schizophrenia; bipolar disorder & depressive disorder. Quetiapine is an atypical antipsychotic. Quetiapine is a dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-ht 1a and 5-ht2 receptors. With a lower affinity, this agent also reversibly binds to dopamine d1 and d2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine h1 receptors. Quetiapine Is White Solid Powder. It Is Soluble In Dmso, And Water With Melting Point Of 223.40°C.

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Isosorbide Dinitrate

  • Supplied By UMA Brothers, India

We are offering isosorbide dinitrate is a vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action. Isosorbide dinitrate is a nitrate vasodilator. The physiologic effect of isosorbide dinitrate is by means of vasodilation. The chemical classification of isosorbide dinitrate is nitrates. Isosorbide dinitrate is the dinitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide dinitrate relaxes vascular smooth muscle by formation of the free radical nitric oxide (no), which is identical to the endothelium-derived relaxing factor (edrf). No activates guanylyl cyclase, thereby increasing the synthesis of cgmp within smooth muscle, resulting in dephosphorylation of light chain myosin and relaxation of peripheral arteries and veins. In addition, isosorbide dinitrate relaxes coronary arteries, thereby increasing the blood circulation through the ischemic area. synonyms: [(3s, 3as, 6r, 6as)-3-nitrooxy-2, 3, 3a, 5, 6, 6a-hexahydrofuro[3, 2-b]furan-6-yl] nitrate cas number: 87-33-2, mol. Formula: c6h8n2o8, mol.weight: 236.14 isosorbide dinitrate is a white to light yellow crystal powder. It is soluble in acetone alcohol ether, in chloroform, in water with melting point of 700°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Piroxicam

  • Supplied By UMA Brothers, India

We are offering piroxicam. Piroxicam is a cyclooxygenase inhibiting, non-steroidal antiinflammatory agent (nsaid) that is well established in treating rheumatoid arthritis and osteoarthritis & used for musculoskeletal disorders dysmenorrhea and postoperative pain. Its long half-life enables it to be administered once daily. It is a nonsteroidal antiinflammatory drug. The mechanism action of piroxicam is as a cyclooxygenase inhibitor. The chemical classi- fication of piroxicam is nonsteroidal antiinflammatory compounds. Piroxicam is a nonsteroidal oxicam derivative with anti-inflammatory, antipyretic and analgesic properties. As a non-selective, nonsteroidal anti-inflammatory drug (nsaid), piroxicam binds and chelates both isoforms of cyclooxygenases (cox1 and cox2), thereby stalling phospholipase a2 activity and conversion of arachidonic acid into prostaglandin precursors at the rate limiting cyclooxygenase enzyme step. This results in inhibition of prostaglandin biosynthesis. As a second, independent effect, piroxicam inhibits the activation of neutrophils thereby contributing to its overall anti-inflammatory effects. synonyms: 4-hydroxy-2-methyl-1, 1-dioxo-n-pyridin-2-yl-1$l^ {6}, 2-benzothiazine-3-carboxamide cas number: 36322-90-4, mol. Formula: c15h13n3o4s, mol.weight: 331.35 piroxicam is off-white to pale yellow solid powder. It is soluble in water (partly miscible), dmso (25 mgml warm), ethanol (5 mgml warm), chloroform, ethyl acetate, dmf (~20 mgml), and 1:1 solution of dmso: pbs (ph 7.2) (~0.5 mgml) with melting range of 198°c to 200°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Efavirenz

  • Supplied By UMA Brothers, India

We are offering efavirenz is a human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitor. The mechanism of action of efavirenz is as a non-nucleoside reverse transcriptase inhibitor, cytochrome p450 3a inducer, cytochrome p450 2b6 inducer, cytochrome p450 2c9 inhibitor, cytochrome p450 2c19 inhibitor, and cytochrome p450 3a4 inhibitor. The chemical classification of efavirenz is non-nucleoside analog. Efavirenz is a synthetic non-nucleoside reverse transcriptase (rt) inhibitor with antiviral activity. Efavirenz binds directly to the human immunodeficiency virus type 1 (hiv-1) rt, an rna-dependent dna polymerase, blocking its function in viral dna replication. In combination with other antiretroviral drugs, this agent has been shown to significantly reduce hiv viral load, retarding or preventing damage to the immune system and reducing the risk of developing aids. Efavirenz induces activity of the cytochrome p450 system, accelerating its own metabolism. synonyms: (4s)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1h-3, 1-benzoxazin-2-one cas number: 154598-52-4, mol. Formula: c14h9clf3no2, mol.weight: 315.67 efavirenz is a white to slightly pink crystalline powder. It is soluble in methanol with melting range of 134°c to 136°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Azithromycin

  • Supplied By UMA Brothers, India

We are offering azithromycin. Azithromycin is a semi-synthetic macrolide antibiotic structurally related to erythromycin. It has been used in the treatment of mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis. Azithromycin anhydrous is a macrolide antimicrobial. The chemical classification of azithromycin anhydrous is macrolides. Azithromycin is an azalide antibiotic, which inhibits the growth of gram negative bacteria, such as haemophilus influenza. Azithromycin functions by interfering with 50s ribosomal subunit formation and translation, which inhibits the formation of proteins essential for bacterial survival studies involving capillary electrophoresis suggest that azithromycin can be used as a chiral selector for enantiomeric separation of compounds. In addition, azithrmycin can be used to increase chloride efflux and selectively reduces tumor necrosis factor α in human cystic fibrosis cells. Furthermore, azithromycin reduces lps-induced pulmonary neutrophilia in mice, via suppressing the expression of il-1β. synonyms: (2r, 3s, 4r, 5r, 8r, 10r, 11r, 12s, 13s, 14r)-11-[(2s, 3r, 4s, 6r)-4-(dimethy lamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3, 4, 10-trihydroxy-13-[(2r, 4r, 5s, 6s)-5-hydroxy-4-methoxy-4 cas number: 83905-01-5 mol. Formula: c38h72n2o12, mol.weight: 748.98 azithromycin is a white crystalline powder. It is soluble in dmso (100 mgml at 25 °c), ethanol (100 mgml at 25 °c), water (

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Miconazole

  • Supplied By UMA Brothers, India

We are offering miconazole. Miconazole is an imidazole antifungal agent, developed by janssen pharmaceutica, commonly applied topically to the skin or tomucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol a critical component of fungal cell membranes. It can also be used against certain species of leishmania protozoa which are a type of unicellular parasites that also contain ergosterol in their cell membranes. In addition to its antifungal & antiparasitic actions, it also has some antibacterialproperties. It is marketed in various formulations under various brand names. Miconazole is also used in ektachrome film developing in the final rinse of the kodak e-6 process and similar fuji cr-56 process, replacing formaldehyde. Fuji hunt also includes miconazole as a final rinse additive in their formulation of the c-41ra rapid access color negative developing process. synonyms: 1-[2-(2, 4-dichlorophenyl)-2-[(2, 4-dichlorophenyl) methoxy] ethyl] imidazole cas number: 22916-47-8, mol. Formula: c18h14cl4n2o, mol.weight: 416.13 miconazole is a white to white to pale cream crystalline powder. It is soluble in water 1g100ml (20 °c with melting range of 159°c to 163°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Stanozolol

  • Supplied By UMA Brothers, India

We are offering stanozolol. Stanozolol is a synthetic steroid that has anabolic and androgenic properties. Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema. Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes. synonyms: stanozol; stanozolol; stanazol; winstrol l; 1, 10a, 12a-trimethyl-1, 2, 3, 3a, cas number: 10418-03-8, mol. Formula: c21h32n2o, mol.weight: 328.49 stanozolol is a white crystalline solid. It is soluble inethyl acetate and acetone; very slightly sol in benzene with melting range of 229°c to 242°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Nevirapine

  • Supplied By UMA Brothers, India

We are offering nevirapine. Nevirapine is a potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of hiv infections and aids. Nevirapine is a human immunodeficiency virus 1 non-nucleoside analog reverse transcriptase inhibitor. The mechanism of action of nevirapine is as a non-nucleoside reverse transcriptase inhibitor, cytochrome p450 3a inducer, and cytochrome p450 2b6 inducer. The chemical classification of nevirapine is non-nucleoside analog. Nevirapine is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces hiv viral loads & increases cd4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing aids. synonyms: 11-cyclopropyl-4-methyl-5h-dipyrido [2, 3-e: 2', 3'-f] [1, 4] diazepin-6-one cas number: 129618-40-2, mol. Formula: c15h14n4o, mol.weight: 266.3 nevirapine is a white to white crystalline powder. It is soluble in chloroform and methanol with melting range of 246°c to 248°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Aripiprazole

  • Supplied By UMA Brothers, India

We are offering aripiprazole. Aripiprazole is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of serotonin receptor, 5-ht1a and dopamine d2 receptors, where it also functions as a post-synaptic antagonist, and an antagonist of serotonin receptor, 5-ht2a. Aripiprazole is an atypical antipsychotic. Aripiprazole is a quinoline derivate and atypical anti-psychotic agent. Aripiprazole has partial agonistic activity at dopamine d2 receptors as well as potent antagonistic activity on serotonin 5-ht2a receptors. This drug stabilizes dopamine and serotonin activity in the limbic and cortical system. Aripiprazole is used in managing symptoms of schizophrenia and of acute manic and mixed episodes associated with bipolar I disorders. synonyms: 7-[4-[4-(2, 3-dichlorophenyl) piperazin-1-yl] butoxy]-3, 4-dihydro-1h-quinolin-2-one cas number: 129722-12-9 mol. Formula: c23h27cl2n3o2, mol.weight: 448.39 aripiprazole is a colourless flake crystalline solid. It is soluble in water with melting point of 139°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Lansoprazole

  • Supplied By UMA Brothers, India

We are offering lansoprazole. Lansoprazole is a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. Lansoprazole prodrug is converted to an active sulfonamide derivative in the acidic environment of the gastric parietal cell; the sulfonamide derivative binds to the gastric proton pump h+k+ atpase and forms a stable disulfide bond with the sulfhydryl group near the potassium-binding site on the luminal side, resulting in inactivation of the atpase and a reduction in gastric acid secretion. This agent does not have anticholinergic or histamine h2 -receptor antagonistic properties. A 2, 2 2-trifluoroethoxypyridyl deri- vative of timoprazole that is used in therapy of stomach ulcers & zollinger-ellison syndrome. The drug inhibits h (+) –k (+)-exchanging atpase which is found in gastric parietal cells. Lansoprazole is a racemic mixture of (r)- and (s)-isomers. synonyms: 2-[[3-methyl-4-(2, 2, 2-trifluoroethoxy) pyridin-2-yl] methylsulfinyl]-1h-benzimidazole cas number: 103577-45-3, mol. Formula: c16h14f3n3o2s, mol.weight: 369.36 lansoprazole is white crystalline powder. It is soluble in methanol, ethanol (14 mgml at 25 °c), dmf (~30 mgml), and dmso (74 mgml at 25 °c) insoluble in water with melting range of 173°c to 175°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Metoprolol

  • Supplied By UMA Brothers, India

We are offering metoprolol. Metoprolol is a selective adrenergic beta-1 blocking agent that is commonly used to treat angina pectoris; hypertension; & cardiac arrhythmias. Metoprolol is a cardioselective 1-adrenergic blocking agent used for acute myocardial infarction (mi), heart failure, angina pectoris & mild to moderate hypertension. It may also be used for supraventricular & tachyarrhythmias and prophylaxis for migraine headaches. metoprolol is structurally similar to bisoprolol, acebutolol and atenolol in that it has two substituents in the para position of the benzene ring.the 1-selectivity of these agents is thought to be due in part to the large substituents in the para position. At low doses, metoprolol selectively blocks cardiac 1-adrenergic receptors with little activity against 2-adrenergic receptors of the lungs & vascular smooth muscle. Receptor selectivity decreases with higher doses. Unlike propranolol & pindolol, metoprolol does not exhibit membrane-stabilizing or intrinsic sympa thomimetic activity. Membrane-stabilizing effects are only observed at doses much higher than those needed for -adrenergic blocking activity. Metoprolol possesses a single chiral centre and is administered as a racemic mixture. synonyms: 1-[4-(2-methoxyethyl) phenoxy]-3-(propan-2-ylamino) propan-2-ol cas number: 37350-58-6, mol. Formula: c15h25no3, mol.weight: 267.36 metoprolol is a pink solid powder. It is soluble in water, and dmf with melting point of 120°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Perindopril

  • Supplied By UMA Brothers, India

We are offering perindopril is an angiotensin-converting enzyme inhibitor. It is used in patients with hypertension & heart failure. Perindopril is an angiotensin converting enzyme inhibitor. The mechanism of action of perindopril is as an angiotensin-converting enzyme inhibitor. Perindopril is a non-sulfhydryl angiotensin converting enzyme (ace) inhibitor with antihypertensive activity. Upon hydrolysis, perindopril is converted to its active form perindoprilat, inhibiting ace & the conver- sion of angiotensin I to angiotensin ii; consequently, angiotensin ii-mediated vasoconstriction & angiotensin ii-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis & natriuresis ensue. synonyms: (2s, 3as, 7as)-1-[(2s)-2-[[(2s)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2, 3, 3a, 4, 5, 6, 7, 7a-octahydroindole-2-carboxylic acid cas number: 82834-16-0, mol. Formula: c19h32n2o5, mol.weight: 368.47 perindopril is a light pink solid powder. It is soluble in water, chloroform, and methanol with melting range of 100°c to 101°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Topiramate Liquid

  • Type Pure
  • Purity 100%
  • Form Liquid
  • Grade Superior
  • Usage Industrial
  • Stroage Cool & Dry Place
  • Packing Drum
  • Supplied By UMA Brothers, India

Topiramate is a sulfamate-substituted monosaccharide with anti- convulsant property. Although the mechanism of action has not been fully elucidated, topiramate antagonizeskainateampa subtype of the glutamate receptors, which are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. This antagonistic action results in stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing & decreasing propagation of synaptic impulses, thereby impedes seizure occurrences. In addition, this agent augments gamma-aminobenzoic acid (gaba) activity & thereby attenuating gabanergic inhibitory transmission.

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Zaleplon

  • Supplied By UMA Brothers, India

We are offering zaleplon. Zaleplon is a gamma-aminobutyric acid a receptor agonist. The mechanism of action of zaleplon is as a gaba an agonist. The physiologic effect of zaleplon is by means of central nervous system depression. Zaleplon is a nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative anxiolytic & muscle relaxant properties. zaleplon interacts with the gamma-aminobutyric acid (gaba) -a receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of gaba. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the gaba-achloride ion channel receptor complex and potentiates t-butyl-bicyclophospho- rothionate (tbps) binding. synonyms: n-[3-(3-cyanopyrazolo [1, 5-a] pyrimidin-7-yl) phenyl]-n-ethylacetamide cas number: 151319-34-5, mol. Formula: c17h15n5o, mol.weight: 305.33 zaleplon is an off-white powder. It is easily soluble in methanol (sparingly), and dmso with melting range of 186°c to 187°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Ezetimibe

  • Supplied By UMA Brothers, India

We are offering ezetimibe ezetimibe is an azetidine derivative and anticholesteremic agent that inhibits intestinal sterol absorption. It is used to reduce total cholesterol; ldl cholesterol, and apolipoproteins b in the treatment of hyperlipidemias. Ezetimibe is a dietary cholesterol absorption inhibitor. The physiologic effect of ezetimibe is by means of decreased cholesterol absorption. Ezetimibe is an azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe appears to interact physically with cholesterol transporters at the brush border of the small intestine and inhibits the intestinal absorption of cholesterol and related phytosterols. As a result, ezetimibe causes a decrease in the level of bloodcholesterol or an increase in the clearance of cholesterol from the bloodstream. Overall, the following effects observed are a reduction of hepatic cholesterol stores and a reduction of total cholesterol, ldl cholesterol, and other triglycerides in the blood. synonyms: (3r, 4s)-1-(4-fluorophenyl)-3-[(3s)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl) azetidin-2-one cas number: 163222-33-1, mol. Formula: c24h21f2no3, mol.weight: 409.43 ezetimibe is a white solid powder. It is soluble in water (

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Gliclazide

  • Supplied By UMA Brothers, India

We are offering gliclazide. Gliclazide is an oral sulfonylurea hypoglycemic agent which stimulates insulin secretion. Gliclazide is a short-acting, relatively high-potency, second-generation sulfonylurea compound with hypoglycemic activity. Gliclazide also increases peripheral insulin sensitivity. This agent is metabolized by cyp2c9. synonyms: 1-(3, 3a, 4, 5, 6, 6a-hexahydro-1h-cyclopenta[c] pyrrol-2-yl)-3-(4-methylphenyl) sulfonylurea cas number: 21187-98-4, mol. Formula: c15h21n3o3s, mol.weight: 323.41 gliclazide is a white crystalline powder. It is soluble in chloroform with melting range of 180°c to 182°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Ramipril

  • Supplied By UMA Brothers, India

We are offering ramipril is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat. Ramipril is an angiotensin converting enzyme inhibitor. The mechanism of action of ramipril is as an angiotensin-converting enzyme inhibitor. Ramipril is a prodrug and nonsulfhydryl angiotensin converting enzyme (ace) inhibitor with antihypertensive activity. Ramipril is converted in the liver by de-esterification into its active form ramiprilat, which inhibits ace, thereby blocking the conversion of angiotensin I to angiotensin ii. This abolishes the potent vasoconstrictive actions of angiotensin ii & leads to vasodilatation. This agent also causes an increase in bradykinin levels and a decrease in angiotensin ii-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. synonyms: (2s, 3as, 6as)-1-[(2s)-2-[[(2s)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3, 3a, 4, 5, 6, 6a-hexahydro-2h-cyclopenta[b]pyrrole-2-carboxylic acid cas number: 87333-19-5, mol. Formula: c23h32n2o5, mol.weight: 416.51 ramipril is a white solid powder. It is soluble in water (

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Tinidazole

  • Supplied By UMA Brothers, India

We are offering tinidazole. tinidazole is a nitroimidazole antitrichomonal agent effective against trichomonas vaginalis, entamoeba histolytica, and giardia lamblia infections. Tinidazole is a nitroimidazole antimicrobial. The chemical classification of tinidazole is nitroimidazoles. Tinidazole is a 5-nitroimidazole derivative with antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized & yields nitrite anions & metronidazole. Metronidazole's nitro group in turn is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and dna strand breaks with multiple hits having an additive effect and ultimately leading to cell death. synonyms: 1-(2-ethylsulfonylethyl)-2-methyl-5-nitroimidazole cas number: 19387-91-8, mol. Formula: c8h13n3o4s, mol.weight: 247.27 tinidazole is a white crystalline solid powder. It is soluble in chloroform and methanol insoluble in water with melting range of 127°c to 128°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Citalopram

  • Supplied By UMA Brothers, India

We are offering citalopram. Citalopram is a furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition. Citalopram is a bicyclic phthalene derivative and selective serotonin reuptake inhibitor (ssri), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotran smitter serotonin (5-ht) in presynaptic cells in the central nervous system, thereby increasing levels of 5-ht within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased seroto- nergic neurotransmission results in antidepressive and anxiolytic effects. synonyms: 1-[3-(dimethylamino) propyl]-1-(4-fluorophenyl)-3h-2-benzofuran-5-carbonitrile cas number: 59729-33-8, mol. Formula: c20h21fn2o, mol.weight: 324.39 citalopram is a white powder. It is soluble in water (4 mgml), methanol, dmso (25 mgml), and ethanol (20 mgml) with melting range of 182°c to 183°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Omeprazole

  • Supplied By UMA Brothers, India

We are offering omeprazole. Omeprazole is a 4-methoxy-3, 5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of stomach ulcers and zollinger-ellison syndrome. The drug inhibits an h (+)-k (+)-exchanging atpase which is found in gastric parietal cells. A highly effective inhibitor of gastric acid secretion used in the therapy of stomach ulcers and zollinger-ellison syndrome. Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles that suppress gastric acid secretion by specific inhibition of the h+ k+ atpase enzyme system at the secretory surface of the gastric parietal cell. synonyms: 6-methoxy-2-[(4-methoxy-3, 5-dimethylpyridin-2-yl) methyl sulfinyl]-1h-benzimidazole cas number: 73590-58-6, mol. Formula: c17h19n3o3s, mol.weight: 345.42 omeprazole is white to white crystalline powder. It is soluble in water (0.5 mgml), dmso (25 mgml), and ethanol (4.5 mgml) with melting range of 156.2°c to 157.2°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Rafoxanide

  • Supplied By UMA Brothers, India

rafoxanide confirms to the highest standards for use in all dosage forms. The rafoxanide is ideal for veterinary use. The product complies with bp vet. Our rafoxanide has good stability & consistency. Vmf or drug master file - open part is available to assure about the quality standards of the products. Rafoxanide is available with various micron sizes for use in suspension grade, oral suspension or drenches. description : case no. : 37052 - 78 -9 molecular formula : c19h11cl2l2no3 molecular weight : 626.01 chemical name : 3� chloro 4� (p chlorophenoxy) 3, 5 - diiodo salicylanilide therapeutic category : anthelmintics specifications : appearance : a grayish white to brown powder solubility : practically insoluble in water, soluble in 25 parts of acetone in ho parts of chloroform & in 35 parts of ethyl acetate, slightly soluble in methanol, loss on drying (at 90 degree celsius under vacuum for 4 hrs) - nmt 0.5% related substances (by tlc) as per bp vet sulphated ash : nmt 0.1%, assay - 98 - 101% packing : offered in export worthy drums of 25/50 kilos shipping caution : it requires specific type of shipping as it is toxic in nature

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Allopurinol

  • Supplied By UMA Brothers, India

We are offering allopurinol is axanthine oxidase inhibitor that decreases uric acid production. It also acts as an antimetabolite on some simpler organisms. Allopurinol is a xanthine oxidase inhibitor. The mechanism of action of allopurinol is as a xanthine oxidase inhibitor. Allopurinol is a structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. The massive cell lysis associated with the treatment of some malignancies. Synonyms: 1, 2-dihydropyrazolo [3, 4-d] pyrimidin-4-one cas number: 315-30-0 mol. Formula: c5h4n4o, mol.weight: 136.11 allopurinol is a fluffy white to off-white powder. It is insoluble in water with melting point of 300°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Finasteride

  • Supplied By UMA Brothers, India

We are offering finasteride. Finasteride is an orally active 3-oxo-5-alpha-steroid 4-dehydrogenase inhibitor. It is used as a surgical alternative for treatment of benign prostatic hyperplasia. Finasteride is a 5-alpha reductase inhibitor. The mechanism of action of finasteride is as a 5-alpha reductase inhibitor. Finasteride is a synthetic 4-azasteroid compound. finasteride competitively binds to and inhibits steroid type ii 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (dht) and reducing serum dht levels.the reduction in serum dht levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation. synonyms: (1s, 3as, 3bs, 5ar, 9ar, 9bs, 11as)-n-tert-butyl-9a, 11a-dimethyl-7-oxo-1, 2, 3, 3a, 3b, 4, 5, 5a, 6, 9b, 10, 11-dodecahydroindeno[5, 4-f]quinoline-1-carboxamide cas number: 98319-26-7, mol. Formula: c23h36n2o2, mol.weight: 372.54 finasteride is off-white crystalline powder. It is soluble in water (0.05 mgml), dmso (75 mgml at 25 °c), ethanol (75 mgml), methanol, and chloroform with melting range of 252°c to 254°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Norfloxacin

  • Supplied By UMA Brothers, India

We are offering norfloxacin. Norfloxacin is a synthetic, broad-spectrum fluoroquinolone with antibacterial activity. Norfloxacin inhibits activity of dna gyrase, thereby blocking bacterial dna replication.norfloxacin concentrates in the renal tubules and bladder and is bactericidal against a wide range of aerobic gram-positive and gram-negative organisms.norfloxacin inhibits bacterial dna gyrase. Norfloxacin is a quinolone antimicrobial. The chemical classification of norfloxacin is quinolones. synonyms: 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid cas number: 70458-96-7, mol. Formula: c16h18fn3o3, mol.weight: 319.33 norfloxacin is off-white to light yellow cryst powder. It is soluble in dmso and methanol (sparingly) with melting range of 210°c to 211°c. standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Cinnarizine

  • Supplied By UMA Brothers, India

We are offering cinnarizine. Cinnarizine is a piperazine derivative having histamine h1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces parkinsonian disorders. Cinnarizine is an anti-histaminic drug which is mainly used for the control of vomiting due to motion sickness. It acts by interfering with the signal transmission between vestibular apparatus of the inner ear and the vomiting centre of the hypothalamus. The disparity of signal processing between inner ear motion receptors and the visual senses is abolished, so that the confusion of brain whether the individual is moving or standing is reduced. Vomiting in motion sickness is actually a physiological compensatory mechanism of the brain to keep the individual from moving so that it can adjust to the signal perception. Cinnarizine could be also viewed as a nootropic drug because of its vasorelaxating abilities (due to calcium channel blockage), which happen mostly in brain. It is also effectively combined with other nootropics, primarily piracetam; in such combination each drug potentiate the other in boosting brain oxygen supply. synonyms: 1-benzhydryl-4-[(e)-3-phenylprop-2-enyl] piperazine cas number: 298-57-7, mol. Formula: c26h28n2, mol.weight: 368.51 cinnarizine is a white powder. It is soluble in chloroform with melting range of 117°cto 120°c. Standard: offered of pharmaceutical grade bpuspep packing: offered in export worthy packing of 25 kilos or as per our customer requirements

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Dextromethorphan Hydrobromide

  • Synonyms Dextromethorphansigmareference*Standard; Dmhm; D-3-Methoxy-N-Methylmorphinan Hydrobromide
  • CAS Number 6700-34-1
  • MOL. Formula C18H28BRNO2
  • MOL. Weight 370.32
  • Standard Offered of Pharmaceutical Grade BP/USP/EP
  • Packing Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements
  • Supplied By UMA Brothers, India

Methyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center.this compound is an nmda receptor antagonist (receptors, n-methyl-d-aspartate) and acts as a non-competitive channel blocker. Dextromethorphan hydrobromide is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity. Dextromethorphan Hydrobromide Is A White Solid Powder. It Is Soluble In Chloroform And Methanol With Melting Range Of 116°C TO 119°C.

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Fluconazole Powder

  • Supplied By UMA Brothers, India

Fluconazole Used for Treating and Preventing Certain Yeast and Fungal Infections. Fluconazole is An Azole Antifungal and Kills Sensitive Fungi By Interfering with the Formation of the Fungal Cell Membrane fluconazole is An Antifungal Medication that is Administered Orally or Intravenously. It is Used to Treat a Variety of Fungal Infections, Especially candida infections of the Vagina ("yeast Infections'), Mouth, Throat, and Bloodstream. It is also Used to Prevent Infections in People with Weak Immune Systems, Including Those with Neutropenia Due to Cancer Chemotherapy, Transplant Patients, Those with Advanced Hiv Infections, and Premature Babies. Its Mechanism of Action Involves Interfering with Synthesis of the Fungal Cell Membrane. Fluconazole, the First of a New Subclass of Synthetic Triazole Antifungal agents, is Available as Tablets for Oral Administration, as a Powder for Oral Suspension, and as a Sterile Solution for Intravenous Use in Glass and Plastic Containers.

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Serratiopeptidase

  • Supplied By UMA Brothers, India

serratiopeptidase is a type of enzyme which is white in color. The product is used for pain inflammation conditions such as arthritis, minor muscle trauma, sinusitis, bronchitis, carpal tunnel, syndrome etc. It is primarily a proteolytic enzyme insolated from the non-pathogenic enterobacteria. Serratia e15 is found in silkworms. Serratiopeptidase is a naturally occurring, physiological agent with no inhibitory effects on prostagladins and is devoid of gastrointestinal side effects. Serratiopeptidase has been shown to be effective in transferring various antibiotics such as pencillin, gentamycin and cegatoxime to the site of infection. It could significantly enhance effectiveness of antibiotics against biofilm and can inhibit biofilm formation. Serratiopeptidase is a viable alternative to salicylates, ibuprofen and many more potent nsaids. it is soluble in water, insoluble in alcohol & ether, loss of drying 5% activity 2200-2500 u/mg. Serratiopeptidase is derived from the bacteria belonging to the genus serratia. It can be absorbed through the intestines and transported directly into the blood stream. It binds to alpha 2 - macroglobulin in the blood in the ratio of 1:1, which helps to mask its antigenicity but retains its enzymatic activity and is slowly transferred to the site of infection. functions : serratiopeptidase acts upon inflammation by thinning the fluids in the body that collect around injured areas. This also enhances tissue repair and reduces pain. Pain is also reduced by this enzymes ability to block amines. Serratiopeptidase also has the unique ability to dissolve the dead and damages tissue that is by product of healing response without harming living tissue. benefits : super protein : digesting enzyme which breaks down non-living matter in the human body powerful anti : inflammatory, aids treatment of fibromyaliga, arthritis, rheumatism, multiple, sclerosis etc., cancer and tumor preventative no side effects or stomach irritation improving blood circulation by reducing levels of dead tissue digests scar tissue build up from surgeries or injuries fights building up of fibrin reduces blood : cotscysts & arterial plaque anti - edemic prevents swelling and fluid retention shown to help chronic sinusitis sufferers

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Tacrolimus

  • Synonyms 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;
  • Cas Number 104987-11-3
  • Mol. Formula C44H69NO12
  • Mol.weight 804.02
  • Standard Offered of Pharmaceutical Grade BP/USP/EP
  • Packing Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements
  • Supplied By UMA Brothers, India

Tacrolimus is a macrolide isolated from the culture broth of a strain of streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of t-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Tacrolimus anhydrous is a calcineurin inhibitor immunosuppressant. The mechanism of action of tacrolimus anhydrous is as a calcineurin inhibitor. Anhydrous from of tacrolimus, a macrolide isolated from streptomyces tsukubaensis. Tacrolimus binds to the fkbp-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo & prevents the activation of t-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent. Tacrolimus Is A White Crystalline Solid Powder. It Is Soluble In Chloroform And Methanol With Melting Range Of 90°C TO 92°C.

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Bicalutamide

  • Synonyms N-[4-CYANO-3-(Trifluoromethyl) Phenyl]-3-(4-Fluorophenyl) Sulfonyl-2-Hydroxy-2-Methylpropanamide
  • CAS Number 90357-06-5
  • MOL. Formula C18H14F4N2O4S
  • MOL. Weight 430.37
  • Standard Offered of Pharmaceutical Grade BP/USP/EP
  • Packing Offered in Export Worthy Packing of 25 Kilos or as per Our Customer Requirements
  • Supplied By UMA Brothers, India

Bicalutamide is a synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It binds to the androgen receptor. Bicalutamide Is A Off-White Crystalline Solid. It Is Slightly Soluble In Chloroform And Absolute Ethanol; Sparingly Soluble In Methanol; Soluble In Acetone And Tetrahydrofuan Practically Insoluble In Water At 37 Deg C (5 Mg/1000 Ml) With Melting Range Of 191°C To 193°C .

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