Niksan Pharmaceutical

Gidc Industrial Estate, Ankleshwar, Gujarat

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the URSODEOXYCHOLIC ACIDfinished formulations moreover URSODEOXYCHOLIC ACID API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Ursodeoxycholic Acid API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader ofUrsodeoxycholic Acid inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Ursodeoxycholic Acid to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Ursodeoxycholic Acid formulations in many countries for many years. Niksan pharmaceutical currently exports Ursodeoxycholic Acid API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

URSODEOXYCHOLIC ACIDUrsodeoxycholic acid (UDCA), also known as ursodiol, belongs to the class ofbile acids.Specifically, it's a naturally occurring dihydroxy bile acid.It is also classified as a tertiary bile acid.

SYNONYSMS:Ursodiol

IUPAC NAME: (4R)-4-[(1R, 3aS, 3bR, 4S, 5aS, 7R, 9aS, 9bS, 11aR)-4, 7-dihydroxy-9a, 11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid

CAS NO:128-13-2

FORMULA:C24H40O4

MOLECULAR MASS: 392.56g/mol

STORAGE CONDITIONS:Ursodiol should be stored atroom temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place. Store in a tightly closed container.

HOW TO USE:Four to six tablets of 150 mg, two to three tablets of 300 mg or two tablets of 450 mg per day (600- 900 mg ursodeoxycholic acid per day).Two tablets should always be taken after dinner. When taking a dose two or three times daily: for example, one tablet after lunch and two tablets after dinner.

HOW URSODEOXYCHOLIC ACID WORKS:Ursodeoxycholic acid (UDCA), also known as ursodiol, worksthrough multiple mechanisms to protect the liver and dissolve cholesterol gallstones.It alters the composition of bile, reduces cholesterol saturation in bile, protects liver cells, and modulates the immune system.

SIDE EFFECTS OF URSODEOXYCHOLIC ACID: The normal side effects caused by Ursodeoxycholic Acid are Acid or sour stomach, belching bloating or swelling of face, arms, hands, lower legs, or feet, difficulty with moving, loss or thinning of the hair, rapid weight gain, stomach discomfort or upset, tingling of the hands or feet, unusual weight gain or loss.

CDSCO APPROVAL:

Ursodeoxycholic acid SR capsules 01/12/2004

Ursodeoxycholic Acid 300/600 SR Tablets (Additional Strength) 08.12.08

Ursodeoxycholic acid 12/04/2001

Ursodeoxycholic acid tablets 600mg 30.01.08

Ursodeoxycholic Acid Suspension 125mg/5ml and 250 mg /5ml. 11.02.11

Ursodeoxycholic Acid (600mg) S.R Tablet 20/07/2005

FORMULATIONS AVAILABLE IN MARKET:

URSODEOXYCHOLIC ACID 150 MG tablets

URSODEOXYCHOLIC ACID 300 MG tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is the largest manufacturer, Exporter sand supplier of Iguratimod. Iguratimod is a one of the most famous medicine invented by Japanese. Iguratimod is first Launch in India by Niksan Pharmaceutical with manufacturing from first step. Nowadays Niksan Pharmaceutical is one of the leading manufacturer and exporter who manufacturing Iguratimod as well as Intermediates of Iguratimod.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Iguratimod formulations in many countries for many years. Niksan pharmaceutical currently export Iguratimod API and Formulation to countries like Japan, Myanmar, Shrilanka, UAE, Kenya, Vietnam, Australia, Saudi Arabia, United States, United Kingdom, China, and Korea and also in some European countries.

Niksan Pharmaceutical is an Indian based pharmaceutical company so it also supplies and manufactures the Iguratimod to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, and Hyderabad Etc.

Iguratimod is a disease-modifying anti-rheumatic drug (DMARD). It is used in the treatment ofCrohns disease, systemic lupus erythematosus, Wilson's disease, rheumatoid arthritisand

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the CALCIUM LYSINATEfinished formulations moreover Calcium Lysinate API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Calcium Lysinate API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of Calcium Lysinate inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Calcium Lysinate to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Calcium Lysinate formulations in many countries for many years. Niksan pharmaceutical currently exports Calcium Lysinate API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

CALCIUM LYSINATEis a chelated form of calcium, a mineral essential for bone health, muscle function, nerve signaling, and vascular contraction. The lysinate form helps enhance calcium bioavailability and absorption in the body.

SYNONYSMS:Calcium L-lysinate, L-Lysine, calcium salt (2:1), and Bis(L-lysine)calcium salt

IUPAC NAME: Calcium bis(2, 6-diaminohexanoate)

CAS NO:6150-68-1

FORMULA:C12H26CaN4O4

MOLECULAR MASS: 330.44 g/mol

STORAGE CONDITIONS:Store in a cool and dry place. Keep the container tightly closed and away from heat, light, and moisture. Recommended storage temperature: 15C to 30C.

HOW TO USE:Calcium Lysinate is typically used as a dietary supplement. The dosage depends on the individuals calcium requirements and should be determined by a healthcare provider. It may be taken with or without food.

HOW CALCIUM LYSINATE WORKS:Calcium Lysinate works by providing elemental calcium in a chelated form (bound to lysine), which enhances intestinal absorption and minimizes gastrointestinal discomfort. It supports bone mineralization, muscle contraction, and nerve transmission.

PHARMACOKINETICS OF CALCIUM LYSINATE: Chelated calcium forms like Calcium Lysinate are more bioavailable than inorganic salts. They are absorbed in the small intestine and utilized in bone tissue, muscle function, and various metabolic pathways. Unused calcium is excreted via urine and feces

SIDE EFFECTS OF CALCIUM LYSINATE: The normal side effects caused by CALCIUM LYSINATE are Constipation, Bloating, Flatulence, Hypercalcemia (in excessive doses), Nausea (rare), Kidney stone formation (long-term high doses).

PRECAUTIONS: Avoid excessive doses without medical supervision. Patients with a history of kidney stones, hyperparathyroidism, or severe renal impairment should consult their doctor before use. Maintain adequate hydration during supplementation.

FORMULATIONS AVAILABLE IN MARKET:

CALCIUM LYSINATE 500 MG tablets

CALCIUM LYSINATE SACHETS

CALCIUM LYSINATE CAPSULES

CALCIUM LYSINATE SYRUP

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is leading manufacturer and distributer of the Metoclopramide among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Metoclopramide API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Metoclopramide in the domestic level as well as the international market.

Niksan Pharmaceutical provides Metoclopramide API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Metoclopramide API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Metoclopramide is one type of medicationused relieve symptoms caused by slow stomach emptying in people who have diabetes. These symptoms include nausea, vomiting, heartburn, loss of appetite, and feeling of fullness that lasts long after meals.

SYNONYMS: Cerucal, Dihydrochloride, Metoclopramide, Hydrochloride, Metoclopramide, Maxolon, Metaclopramide, Metoclopramide, Metoclopramide Dihydrochloride.

IUPAC NAME:4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide

CAS NO: 364-62-5

FORMULA: C₁₄H₂₂ClN₃O₂

MOLECULAR MASS:299.8g/mol

STORAGE OF METOCLOPRAMIDE:Store at20 to 25C (68 to 77F). [See USP Controlled Room Temperature.] Protect from light by retaining in package until time of use. This product is light sensitive.

APPLICATIONS OF METOCLOPRAMIDE:Metoclopramide is a dopamine receptor antagonist and has been approved by the FDA totreat nausea and vomiting in patients with gastroesophageal reflux disease or diabetic gastroparesis by increasing gastric motility. It is also used to control nausea and vomiting in chemotherapy patients.

HOW TO USE: AdultsAt first, 10 to 15 milligrams (mg) four times a day, taken 30 minutes before symptoms are likely to begin or before each meal and at bedtime, for 4 to 12 weeks. Your doctor may adjust your dose as needed. However, the dose is usually not more than 60 mg per day.

HOW METOCLOPRAMIDE WORKS:It works byincreasing the movements or contractions of the stomach and intestines. It relieves symptoms such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite. Metoclopramide is also used to treat heartburn for patients with gastroesophageal reflux disease (GERD).

CONTRAINDICATIONS OF METOCLOPRAMIDE: Known hypersensitivity to metoclopramide or excipients[44], Gastrointestinal bleeding, Obstruction, Perforation[30].

PHARMACOKINETICS OF METOCLOPRAMIDE: Bilastine haslinear pharmacokinetics in the 2.5220 mg dose range in healthy adult subjects without evidence of accumulation after 14 days of treatment.

SIDE EFFECTS OF METOCLOPRAMIDE: The onset of pharmacological action of metoclopramide is 1 to 3 minutes following an intravenous dose, 10 to 15 minutes following intramuscular administration, and 30 to 60 minutes following an oral dose; pharmacological effects persist for 1 to 2 hours. Metoclopramide is rapidly and well absorbed.

Niksan Pharmaceutical and the Niksan group companies are the worlds top most leading pharmaceutical companies in the exporting, supplying and manufacturing of the Biperiden API and also the finished pharmaceutical products of Biperiden like Biperiden tablets and Biperiden injections. Niksan pharmaceuticals Biperiden product is appreciated widely by our group companies and by the customers all around the world.

Niksan Pharmaceutical is the supplier, manufacturer, supplier, and exporter sand trader in the domestic level as well as the international market.

Niksan Pharmaceutical provides Biperiden API in all over Indian states like Delhi, Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Madhya Pradesh, Haryana, Telangana, Bihar, Karnataka, Kerala, Punjab, Rajasthan, Andhra Pradesh in huge quantity.

Niksan Pharmaceutical also manufacturing, trading, supplying and exporting Biperiden API and Finished formulations in countries of Philippines, Germany, Taiwan, Lebanon, Iran, Ireland, Israel, South Africa, Egypt, Austria, Switzerland, Turkey, Czechia, Greece, Poland, Mexico, Australia, Peru, United States, United Kingdom and many other states.

Biperiden belongs to the anticholinergic class of medicine. Mostly Biperiden is use in the treatment of Parkinson disease worldwide. Dosage forms like oral dosage form (Tablets) and parenteral dosage form (injections) are available in market under the brand name of Akineton.

IUPAC NAME: 1-bicyclo hept-5-en-2-yl-1-phenyl-3-(piperidin-1-yl) propan-1-ol

CAS NO: 541-65-8

FORMULA: C₂₁H₂₉NO

MOLECULAR MASS: 311.46g/mol

STORAGE: Store it in cool dry place. Biperiden is light sensitive drug so keep away from light and also put it in the light resistance container.

APPLICATION: Biperiden is a most widely used as antiparkinson agent it is also use to treat stiffness, tremors, spasms, and poor muscle control of Parkinson's disease.

HOW TO USE: Biperiden is commonly taken with the full glass of water. If taking Biperiden upsets your stomach, take medicine after meal. Maximum dose of Biperiden is 8 tablets (16 mg) per day. The parenteral dosage form must be required to given by medical practitioners or if you have any confusion related to medicine kindly contact your doctor.

CONTRAINDICATIONS: Basically you cannot take the medicine if you have allergic reaction to Biperiden. If you have any bowel disease kindly avoid the use of Biperiden.

Tell your doctor if you have any kidney related disorders. Kindly share the information to doctor if you have any heart disease, epilepsy or ant seizure type disease.

It is also not known whether Biperiden passes into breast milk.so gently do not take Biperiden without first talking to your doctor if you are breast-feeding a baby.

PHARMACOKINETICS: Biperiden is well absorbed through the GI track after oral administration. After the GI administration Biperiden goes to liver and then metabolise there. Although the metabolism of Biperiden is not well known. Excretion of Biperiden is done by urination.

MAJOR AND MINOR SIDE EFFECTS OF BIPERIDEN: There are some minor side effects of Biperiden like eye pain, rash, seizures, dry mouth, upset stomach like side effects are commonly shown in the patient. Some major side effects are also caused by using the Biperiden, but these are some rare side effects like blurred vision, difficulty in urinating, nervousness, hallucinations, fast and irregular heartbeats, and loss of consciousness.

PRECAUTIONS: Biperiden causes blurred vision and drowsiness so kindly avoid driving, operating machinery and performing any hazardous activity. Biperiden cause drowsiness so kindly avoid alcohol when taken medicine. Try to stay in cool places because the threat of heat stroke.

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the EMPAGLIFLOZIN finished formulations moreover EMPAGLIFLOZINAPI. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of EMPAGLIFLOZINAPI and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of EMPAGLIFLOZIN inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the EMPAGLIFLOZIN to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also EMPAGLIFLOZIN formulations in many countries for many years. Niksan pharmaceutical currently exports EMPAGLIFLOZINAPI and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

EMPAGLIFLOZIN is an oral antihyperglycemic agent of the SGLT2 (sodium-glucose co-transporter 2) inhibitor class, used to improve glycemic control in adults with type 2 diabetes mellitus. It also reduces the risk of cardiovascular death in patients with type 2 diabetes and established cardiovascular disease.

SYNONYSMS:Jardiance

IUPAC NAME: (1S)-1, 5-Anhydro-1-C-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-D-glucitol

CAS NO:864070-44-0

FORMULA:C23H27ClO7

MOLECULAR MASS: 450.91 g/mol

STORAGE CONDITIONS:Store at 20C to 25C (68F to 77F). Protect from moisture and light. Store in a tightly closed container in a cool, dry place.

HOW TO USE:The usual starting dose is 10 mg orally once daily in the morning, with or without food. Based on tolerance and clinical response, the dose may be increased to 25 mg once daily. Always use as prescribed by the physician.

HOW EMPAGLIFLOZIN WORKS: Empagliflozin works by inhibiting SGLT2 in the proximal renal tubules. This reduces glucose reabsorption and increases urinaryglucose excretion, thereby lowering blood glucose levels. It also has beneficial effects on blood pressure and weight.

PHARMACOKINETICS OF EMPAGLIFLOZIN:Empagliflozin is rapidly absorbed after oral administration, with peak plasma concentrations occurring at 1.5 hours. It is 86% protein-bound, metabolized mainly by glucuronidation, and excreted via urine and feces. Terminal half-life is approximately 12.4 hours.

SIDE EFFECTS OF EMPAGLIFLOZIN:Urinary tract infections, Increased urination, Genital yeast infections, Dehydration, Hypotension, Increased cholesterol levels, Risk of ketoacidosis (rare), Acute kidney injury (rare)

PRECAUTIONS: Not for use in patients with type 1 diabetes or diabetic ketoacidosis. Monitor renal function before and during treatment. Use cautiously in patients on diuretics, those with low blood pressure, or history of urinary tract infections. Avoid in pregnancy unless necessary.

CDSCO APPROVAL: Emphagliflozin Tablet 10/25 mg 07.05.15

FORMULATIONS AVAILABLE IN MARKET:

EMPAGLIFLOZIN 10 MG Tablets

EMPAGLIFLOZIN 25 MG Tablets

EMPAGLIFLOZIN + METFORMIN Tablets

EMPAGLIFLOZIN + LINAGLIPTIN Tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is leading manufacturer and distributer of the Rivaroxaban among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Rivaroxaban API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Rivaroxaban in the domestic level as well as the international market.

Niksan Pharmaceutical provides Rivaroxaban API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Rivaroxaban API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Rivaroxaban is a factor Xa inhibitor, an anticoagulant. It works by decreasing the clotting ability of the blood and helps prevent harmful clots from forming in the blood vessels. This medicine is available only with your doctor's prescription.

SYNONYMS: Rivaroxaban

IUPAC NAME: 5-chloro-N-[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1, 3-oxazolidin-5-yl]methylthiophene-2-carboxamide

CAS NO: 366789-02-8

FORMULA: C₁₉H₁₈ClN₃O₅S

MOLECULAR MASS:435.88g/mol

STORAGE OF RIVAROXABAN:Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

APPLICATIONS OF RIVAROXABAN:Rivaroxaban is usedto treat deep vein thrombosis (DVT; a blood clot, usually in the leg) and pulmonary embolism (PE; a blood clot in the lung) in adults. Rivaroxaban is also used to prevent DVT and PE from happening again after initial treatment is completed in adults

HOW TO USE: You'll usually take rivaroxabanonce a day just after a meal or snack. It's important to take it with some food to help your body absorb the whole dose. Try to take it at the same time every day.

HOW RIVAROXABAN WORKS:Clotting factors are made by the liver and help stop bleeding. They work with blood cells called platelets that trigger the clotting process to make sure your blood clots properly. Rivaroxaban worksby stopping a clotting factor called factor Xa from working. This thins your blood so it takes longer to clot.

CONTRAINDICATIONS OF RIVAROXABAN: Severe hypersensitivity to rivaroxaban (or any component of the formulation) can occur. Hematologic:Active pathological bleedingis a contraindication for rivaroxaban use. Rivaroxaban should not be taken during pregnancy. If you take rivaroxaban and are planning to get pregnant or you become pregnant while taking it, speak to your doctor or specialist. You will need to be changed to a different medicine.

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the KETOPROFENfinished formulations moreover Ketoprofen API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Ketoprofen API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of Ketoprofen inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Ketoprofen to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Ketoprofen formulations in many countries for many years. Niksan pharmaceutical currently exports Ketoprofen API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

KETOPROFENis a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class. It is used for its analgesic and anti-inflammatory effects in treating pain, inflammation, and fever.

SYNONYSMS:Ketonal, Orudis, Oruvail

IUPAC NAME: (2RS)-2-(3-benzoylphenyl)propanoic acid

CAS NO:22071-15-4

FORMULA:C16H14O3

MOLECULAR MASS: 254.28 g/mol

STORAGE CONDITIONS:Store Ketoprofen at 20C to 25C (68F to 77F). Protect from light, excessive heat, and moisture. Store in a tightly closed container in a dry place.

HOW TO USE:Ketoprofen is usually taken 2 to 3 times daily, depending on the formulation and strength. It should be taken with food or milk to minimize gastrointestinal discomfort. Dosage must be prescribed by a physician based on the condition being treated.

HOW KETOPROFEN WORKS:Ketoprofen works by inhibiting the synthesis of prostaglandins, substances in the body that cause inflammation, pain, and fever. It blocks the enzyme cyclooxygenase (COX), which is essential in prostaglandin production.

PHARMACOKINETICS OF KETOPROFEN:Ketoprofen is rapidly absorbed after oral administration. It binds extensively to plasma proteins (>99%) and is metabolized in the liver via conjugation with glucuronic acid. It is eliminated primarily via the kidneys.

SIDE EFFECTS OF KETOPROFEN:Stomach pain, Nausea, Constipation or diarrhea, Headache, Drowsiness or dizziness, Rash or skin irritation, Increased risk of cardiovascular or gastrointestinal events with long-term use

PRECAUTIONS: Avoid using Ketoprofen in patients with known hypersensitivity to NSAIDs. Use with caution in individuals with peptic ulcer, liver or kidney disorders, or cardiovascular diseases. Always take as prescribed by a doctor. Not recommended during pregnancy and breastfeeding unless absolutely necessary.

FORMULATIONS AVAILABLE IN MARKET:

KETOPROFEN 50 MG tablets

KETOPROFEN 100 MG tablets

KETOPROFEN GEL

KETOPROFEN INJECTON

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

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Niksan Pharmaceutical is one of the leading Manufacturer, Exporter, Distributor, and Supplier of Minoxidil in Ankleshwar, Gujarat, India. To understand the largest accomplishment of clients, we present these products at very realistic price ranges. Niksan Pharmaceutical and Niksan group companies are nowadays one of the largest manufacturers and exporters of Minoxidil API and also finished formulations.

Niksan Pharmaceutical provides Minoxidil to all states of India like Punjab, Rajasthan, Andhra Pradesh, Haryana, Telangana, Bihar, Karnataka, Delhi, Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, and Madhya Pradesh etc. We make all the formulations in the best WHO GMP certified facilities. We also give gift samples to the companies for R&D purpose.

Niksan Pharmaceutical is one of leading manufacturer and exporter of Minoxidil for many years in all the countries like Brazil, Nicaragua, Colombia, Honduras, Ecuador, Mexico, Guatemala, Bolivia, Panama, Costa Rica, Dominican Republic, Uzbekistan, Paraguay, El Salvador, Spain, Peru, Lebanon, Morocco, United Arab Emirates, Tunisia , Portugal, Chile, Italy, Singapore, Bangladesh, Algeria, Philippines, South Africa, Belgium, Sri Lanka, Switzerland, Indonesia, Argentina, Austria, Germany, Romania, Venezuela, Pakistan, Netherlands, Australia, United Kingdom, Canada, France, United States , Ireland, Malaysia, Turkey, Sweden, Egypt, Saudi Arabia, Hong Kong, Croat,

Norway, New Zealand, Greece, Thailand, Denmark, Taiwan, Hungary, Israel, Czechia, South Korea, Iran, Vietnam, Poland, Russia, Ukraine, Japan and many more countries.

Minoxidil is belongs to the antihypertensive agent. It is used in the treatment of hypertension. Minoxidil comes in a solution and foam form which is used in the treatment of male pattern baldness (hair growth).

SYNONYMS: Minossidile, Minoxidil, Minoxidilum.

IUPAC NAME:2, 6-diamino-4-(piperidin-1-yl) pyrimidin-1-ium-1-olate

CAS NO: 38304-91-5

FORMULA: C₉H₁₅N₅O

MOLACULAR MASS: 209.25gmol 1

STORAGE CONDITIONS: Store in cool and dry place. Remember this product is flammable so do no put it near the flames or in kitchen. Keep it away from the reach of the children and pet.

HOW TO USE: Read the instruction given on the label. First wash and clean the scalp area where the Minoxidil solution has to apply. To use the Minoxidil foam first wash your hand with water and dry well your hands and then gently apply the foam on the scalp and massage for 5 to 10 minutes.

HOW MINOXIDIL WORKS: The full mechanism of Minoxidil is not known completely, thus Minoxidil is vasodilator Minoxidil relaxes the blood vessels and by this more oxygen cells will reach to the hair follicles. And by this process hairs gain nutrition by the body.

PHARMACOKINETICS OF MINOXIDIL: Minoxidil is applied by the skin so the absorption of v is done by the skin. Minoxidil works by activating the extracellular signal-regulated kinase (ERK) and Akt and also prevents the death of cells. The half-life of Minoxidil is about 22hrs. Almost 97% of Minoxidil and its residues are excreted by the urination only 3% will be excreted by faeces.

SIDE EFFECTS OF MINOXIDIL: The side effects of Minoxidil are burning; redness and stinging are shown in the patients. If you see some side effects like unwanted facial or body hairs, chest pain, irregular heartbeats, fainting or dizziness contact your doctor. There are some rare side effects like rash, itching or swelling of skin are shown in some patients.

PRECAUTIONS: Before using the product tell your doctor if you have any disease of scalp, hear problem, chest pain, or have any allergic reaction to the Minoxidil. This product is taken clearly when it is needed during the pregnancy period.

CDSCO APPROVAL: Minoxidil topical lotion is approved by CDSCO in India in may-1988,

Minoxidil Topical Solution 5% is approved by CDSCO in India in 16.05.2002

Niksan Pharmaceutical is the largest manufacturer and exporter of the Nandrolone phenyl propionateamong all over the world. Niksan Pharmaceutical is one of biggest the supplier, manufacturer, exporter and distributor of the Nandrolone phenyl propionateAPI and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan pharmaceutical is also large exporters of the API and finished pharmaceutical products of Nandrolone phenyl propionate in many countries for years. The countries where we exporting are Poland, United States, United Kingdom, Brazil, Jordan, Lebanon, Israel, Vietnam, Bangladesh, Paraguay, Argentina, Dominican Republic, Sudan, Hong Kong, Seychelles, Algeria, Iran, Bulgaria, Lithuania, Poland, Sri Lanka, Romania, Uruguay, Russia, Thailand, Afghanistan, Latvia, Lithuania, United Arab Emirates, Seychelles, Peru, Azerbaijan, Venezuela, Morocco, Cote D Ivories, St Lucia, South Korea, Congo, Philippines, Colombia, Burkina Faso, Sudan, Guinea, Djibouti, Netherlands, Nigeria and Germany.

Niksan Pharmaceutical provides API and finished formulations of Nandrolone phenyl propionate in all over Indian states Like Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu Kashmir, Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Etc.

Nandrolone phenyl propionate is one type of anabolic steroid. Nandrolone phenyl propionate used in the treatment of breast cancer and osteoporosis in woman. Nandrolone phenyl propionate given by intra muscular route

SYNONYMS: 19NTPP, Nadrolone phenylpropionate, Nandrolon phenylpropionate, Nandrolone phenylpionate, Nandrolone phenylpropionate, Norandrolone phenyl propionate, Norandrostenolone phenylpropionate, Nortestosterone phenylpropionate, NTPP

IUPAC NAME: [(8R, 9S, 10R, 13S, 14S, 17S)-13-methyl-3-oxo 2, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl] 3-phenylpropanoate

CAS NO: 62-90-8

FORMULA: C₂₇H₃₄O₃

MOLECULAR MASS: 406.6 g/mol

STORAGE CONDITIONS:Store the medicine in room temperature and dry place. Place the medication away from direct heat and light. Do not keep medicine in bathroom or humid place. Keep away from children and pets.

HOW TO USE NANDROLONE PHENYL PROPIONATE: This medication is given intra muscularly. This medication is only given by the doctor or person who has experienceabout it. Do not take over dose of this medicine. Kindly use sterilise injection to give the medication to patients.

HOW NANDROLONE PHENYL PROPIONATE WORKS: Nandrolone phenyl propionate gives androgen effect by binding with the androgen receptor. And after that it binds with the specific nucleotide sequences of the chromosomal DNA and gives the androgenic activity.

PHARMACOKINETICS: Nandrolone phenyl propionate will absorb quickly after the I.M. administration. 58% of the medicine binds with the plasma protein. The half-life of the I.M. dose is 5-7 days. The medicine excreted by the urination.

SIDE EFFECTS: Nandrolone phenyl propionate cause virilism in which women develops masculine characteristics. And this drug also causes erection of penis. The other normal side effects are acne, breast pain, enlarged breast, need of urination. Contact your doctor if you see side effects like chills, insomnia, leg cramps, altered interest in sexual intercourse, cancer of prostate gland, liver problems, high Ca+ in blood.

PRECAUTIONS: Tell your doctor if you are allergic to the medicine. Talk about your medical history if you have any problem like heart problem, liver problem, kidney disease, cancer. Do not take this medication in pregnancy. Kindly avoid alcohol and marijuana products while taking the medication.

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the MONTELUKAST finished formulations moreover Montelukast API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Montelukast API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of Montelukast inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Montelukast to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Montelukast formulations in many countries for many years. Niksan pharmaceutical currently exports Montelukast API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

MONTELUKAST should be used to treat seasonal or perennial allergic rhinitis only in adults and children who cannot be treated with other medications. Montelukast is in a class of medications calledleukotriene receptor antagonists (LTRAs).Montelukast is an orally dosed drug (available as a film-coated tablet, chewable tablet, or oral granules) that is FDA-approved for treating chronic asthma and prophylaxis and preventing exercise-induced bronchoconstriction.

SYNONYSMS:

Niksan Pharmaceutical is leading manufacturer and distributer of the Esomeprazole among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Esomeprazole API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Esomeprazole in the domestic level as well as the international market.

Niksan Pharmaceutical provides Esomeprazole API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Esomeprazole API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Esomeprazole is one type of medication which is works by decreasing the amount of acid made in the stomach.

SYNONYMS: (S)-omeprazole, Esomeprazol, somprazole, Esomeprazole, Esomeprazolum, Perprazole

IUPAC NAME:5-methoxy-2-[(S)-(4-methoxy-3, 5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1, 3-benzodiazole

CAS NO: 119141-88-7

FORMULA: C₁₇H₁₉N₃O₃S

MOLECULAR MASS: 345.4 g/mol

STORAGE OF ESOMEPRAZOLE:Esomeprazole 0.4 and 0.8 mg/mL as the sodium salt in the infusion solutions tested is chemically and physically stable for at least 2 days at room temperature and 5 days under refrigeration.

APPLICATIONS OF ESOMEPRAZOLE: esomeprazole is usedto treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older.

HOW TO USE: Usually take esomeprazoleonce a day, first thing in the morning. You can take it with or without food. If you take esomeprazole twice a day, take 1 dose in the morning and 1 dose in the evening. Swallow tablets and capsules whole with a drink of water (non-fizzy).

HOW ESOMEPRAZOLE WORKS:Esomeprazole is a type of medicine called a proton pump inhibitor (PPI). Proton pumps are enzymes in the lining of your stomach that help it make acid to digest food. Esomeprazoleprevents proton pumps from working properly. This reduces the amount of acid the stomach makes.

CONTRAINDICATIONS OF ESOMEPRAZOLE: contraindicated in patients withknown hypersensitivity to substituted benzimidazoles or to any component of the formulation. Hypersensitivity reactions may include anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, and urticaria

PHARMACOKINETICS OF ESOMEPRAZOLE: Esomeprazole isextensively metabolized in the liver by the cytochrome P450 (CYP) enzyme system. The major part of esomeprazole's metabolism is dependent upon the CYP2C19 isoenzyme, which forms the hydroxy and desmethyl metabolites. The remaining amount is dependent on CYP3A4 which forms the sulphone metabolite.

SIDE EFFECTS OF ESOMEPRAZOLE: Headaches. Make sure you rest and drink plenty of fluids. ., Feeling sick, Try taking esomeprazole with or after a meal or snack. ., Being sick. Take, small, frequent sips of water to avoid, dehydration, Diarrhoea, Constipation, Stomach pain, Farting (flatulence).

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the DAPAGLIFLOZINfinished formulations moreover Dapagliflozin API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Dapagliflozin API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of Dapagliflozin inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Dapagliflozin to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Dapagliflozin formulations in many countries for many years. Niksan pharmaceutical currently exports Dapagliflozin API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

DAPAGLIFLOZINis an oral antihyperglycemic agent that belongs to the class of SGLT2 inhibitors. It is used for the treatment of type 2 diabetes mellitus, and also helps in reducing the risk of hospitalization for heart failure in patients with or without diabetes.

SYNONYSMS:Forxiga, Farxiga

IUPAC NAME: (2S, 3R, 4R, 5S, 6R)-2-[4-chloro-3-[[4-(propyl)phenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3, 4, 5-triol

CAS NO:461432-26-8

FORMULA:C21H25ClO6

MOLECULAR MASS: 408.87 g/mol

STORAGE CONDITIONS:Store at room temperature, between 20C to 25C (68F to 77F). Protect from moisture and light. Store in a tightly closed container.

HOW TO USE:The recommended starting dose is 5 mg once daily, taken in the morning with or without food. The dose can be increased to 10 mg once daily based on individual tolerance and clinical response. Use only as prescribed by your physician.

HOW DAPAGLIFLOZIN WORKS:Dapagliflozin inhibits the sodium-glucose co-transporter 2 (SGLT2) in the proximal renal tubules, reducing the reabsorption of filtered glucose and increasing urinary glucose excretion. This mechanism improves glycemic control and contributes to weight and blood pressure reduction.

PHARMACOKINETICS OF DAPAGLIFLOZIN:Dapagliflozin is rapidly absorbed after oral administration, with peak plasma concentrations occurring within 2 hours. It is extensively protein-bound, metabolized primarily by UGT1A9 into inactive metabolites, and excreted mostly via urine. The terminal half-life is about 12.9 hours.

SIDE EFFECTS OF DAPAGLIFLOZIN: The normal side effects caused by Dapagliflozin are Genital yeast infections, Urinary tract infections, Increased urination, Thirst, Constipation, Hypoglycemia (especially when combined with insulin or sulfonylureas), Dehydration, Rare risk of diabetic ketoacidosis.

PRECAUTIONS: Avoid use in patients with type 1 diabetes or diabetic ketoacidosis. Monitor renal function periodically. Caution should be taken in patients with low blood pressure, elderly patients, or those on diuretics. Use in pregnancy only if clearly needed.

CDSCO APPROVAL:

Dapagliflozin Tablet 5mg/10mg 25.02.15

FORMULATIONS AVAILABLE IN MARKET:

DAPAGLIFLOZIN 5 MG Tablets

DAPAGLIFLOZIN 10 MG Tablets

DAPAGLIFLOZIN + METFORMIN Tablets

DAPAGLIFLOZIN + SAXAGLIPTIN Tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the LAFUTIDINEfinished formulations moreover LAFUTIDINE API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of LAFUTIDINE API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of LAFUTIDINE inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the LAFUTIDINE to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also LAFUTIDINE formulations in many countries for many years. Niksan pharmaceutical currently exports LAFUTIDINE API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

LAFUTIDINEis a histamine H-receptor antagonist used mainly for the treatment of gastric ulcers, gastroesophageal reflux disease (GERD), and other acid-related gastrointestinal disorders. It reduces gastric acid secretion and promotes mucosal defense

SYNONYSMS:FRG-8813, (+)-Lafutidine

IUPAC NAME: 2-[[2-[(furanylmethyl)thio]ethyl]amino]-N-[4-(piperidin-1-ylmethyl)phenyl]acetamide

CAS NO:118288-08-7

FORMULA:C22H29N3O4S

MOLECULAR MASS: 431.55 g/mol

STORAGE CONDITIONS:Store Lafutidine in a tightly closed container at room temperature (20C to 25C). Keep away from excessive heat, moisture, and direct light.

HOW TO USE:Typical adult dose for peptic ulcer 10 mg twice daily or as directed by a physician. Dosage may vary depending on the severity of the condition and patient profile.

HOW LAFUTIDINE WORKS:Lafutidine competitively inhibits histamine H receptors on gastric parietal cells, reducing both basal and stimulated gastric acid secretion. It also enhances mucosal blood flow and stimulates mucus secretion, offering gastroprotective effects.

PHARMACOKINETICS OF LAFUTIDINE:

Absorption: Rapidly absorbed after oral administration.

Metabolism: Extensively metabolized in the liver.

Elimination half-life: 24 hours.

Excretion: Mainly through urine as metabolites.

SIDE EFFECTS OF LAFUTIDINE: The normal side effects caused by lafutidine are Headache, diarrhea, constipation, dry mouth, rash, dizziness, or nausea. Rarely: hypersensitivity reactions, liver enzyme elevation.

PRECAUTIONS: Use with caution in patients with renal or hepatic impairment. Not recommended in pregnancy or lactation unless prescribed. Avoid exceeding recommended dose.

CDSCO APPROVAL:

Lafutidine Tablets-5mg/10mg 16.11.09

Lafutidine Tablets-5mg/10mg 19.01.10

FORMULATIONS AVAILABLE IN MARKET:

LAFUTIDINE 10 MG tablets

LAFUTIDINE + DOMPERIDONE tablets/capsules

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

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Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the PERMETHOL SODIUMfinished formulations moreover Permethol Sodium API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of PERMETHOL SODIUM API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader of Permethol Sodium inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Permethol Sodium to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Permethol Sodium formulations in many countries for many years. Niksan pharmaceutical currently exports Permethol Sodium API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

PERMETHOL SODIUMalso known as

Niksan Pharmaceutical is leading manufacturer and distributer of theBilastineamong the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Bilastine API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Bilastine in the domestic level as well as the international market.

Niksan Pharmaceutical provides BilastineAPI in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Bilastine API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Bilastine is one type ofantihistamine medicationused to treat hives (urticaria), allergic rhinitis and itchy inflamed eyes (allergic conjunctivitis) caused by an allergy. It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H₁receptor, preventing these allergic reactions.

SYNONYMS: Bilastina, Bilastine

IUPAC NAME: 2-[4-(2-4-[1-(2-ethoxyethyl)-1H-1, 3-benzodiazol-2-yl]piperidin-1-ylethyl)phenyl]-2-methylpropanoic acid

CAS NO: 202189-78-4

FORMULA: C₂₈H₃₇N₃O₃

MOLECULAR MASS: 463.6g/mol

STORAGE OF BILASTINE:No special storage conditions are required.

APPLICATIONS OF BILASTINE:Bilastine is an antihistamine medicine used widelyto relieve allergic symptoms like runny nose, sneezing, redness of the nose, watery eyes, itching, and rash. It stops the action of a natural substance called histamine produced in your body during an allergic reaction.

HOW TO USE: 20 mg bilastine (1 tablet) once daily for the relief of symptoms of allergic rhinoconjunctivitis (SAR and PAR) and urticaria. The tablet should be takenone hour before or two hours after intake of food or fruit juice.

HOW BILASTINE WORKS:It worksby blocking the effects of a chemical messenger known as 'histamine', which is naturally involved in allergic reactions. In short, it helps to relieve the discomfort and unpleasant symptoms that occurred due to allergic conditions, like blocked/runny/itchy nose, red/watery eyes, and skin rashes.

CONTRAINDICATIONS OF BILASTINE: Bilastine is contraindicated inpatients who are hypersensitive to the active substance bilastine or to any of the excipients. Special warnings and precautions: Efficacy and safety of bilastine in children under 12 years of age have not been established.

PHARMACOKINETICS OF BILASTINE: Bilastine haslinear pharmacokinetics in the 2.5220 mg dose range in healthy adult subjects without evidence of accumulation after 14 days of treatment.

SIDE EFFECTS OF BILASTINE: In some cases, you may experienceabdominal pain, headache, dizziness, dry mouth, sore throat, nausea, cold-like nose symptoms (in children), or diarrhea (in children). Most of these side effects of BILASTINE do not require medical attention and gradually resolve over time.

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is leading manufacturer and distributer of the Pantoprazole among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Pantoprazole API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Pantoprazole in the domestic level as well as the international market.

Niksan Pharmaceutical provides Pantoprazole API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Pantoprazole API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Pantoprazole is a type of medicine called aproton pump inhibitor (PPI). Proton pumps are enzymes in the lining of your stomach that help it make acid to digest your food. Pantoprazole prevents proton pumps from working properly. This reduces the amount of acid the stomach makes.

SYNONYMS: Pantoprazol, Pantoprazole, Pantoprazolum

IUPAC NAME:6-(difluoromethoxy)-2-[(3, 4-dimethoxypyridin-2-yl)methanesulfinyl]-1H-1, 3-benzodiazole

CAS NO: 102625-70-7

FORMULA: C₁₆H₁₅F₂N₃O₄S

MOLECULAR MASS: 383.37

STORAGE OF PANTOPRAZOLE:Store PROTONIX I.V. for Injection vials at20 - 25C (68 - 77F); excursions permitted to 15 - 30C (59 - 86F). [See USP Controlled Room Temperature.] Protect from light.

APPLICATIONS OF PANTOPRAZOLE:Pantoprazole reduces the amount of acid your stomach makes. It's used forheartburn, acid reflux and gastro-oesophageal reflux disease (GORD) GORD is when you keep getting acid reflux. It's also taken to prevent and treat stomach ulcers.

HOW TO USE: For the treatment of conditions where the stomach produces too much acid, pantoprazole is usually taken twice a day. The delayed-release tablets are usually taken with or without food, and the granules are usually taken 30 minutes before a meal. Take pantoprazole at around the same time(s) every day.

HOW PANTOPRAZOLE WORKS:Proton pumps are enzymes in the lining of your stomach that help it make acid to digest your food. Pantoprazoleprevents proton pumps from working properly. This reduces the amount of acid the stomach makes.

CONTRAINDICATIONS OF PANTOPRAZOLE: Pantoprazole is contraindicated in patients with a history of hypersensitivity to the drug itself, components of the formulation, and/or other benzimidazole PPIs, including omeprazole, lansoprazole, rabeprazole, esomeprazole, or dexlansoprazole.

PHARMACOKINETICS OF PANTOPRAZOLE:Pantoprazole is extensively metabolized in the liver through the cytochrome P-450 system, predominantly by CYP2C19 demethylation with subsequent sulfation and has a serum elimination half-life of about 1.1 hours. Pantoprazole does not accumulate, andits pharmacokinetics are not altered by multiple daily dosing.

SIDE EFFECTS OF PANTOPRAZOLE: Check with your doctor immediately if you or your child hasstomach cramps, bloated feeling, watery and severe diarrhea which may also be bloody sometimes, fever, nausea or vomiting, or unusual tiredness or weakness. Pantoprazole may increase your risk of having fractures of the hip, wrist, and spine.

Niksan Pharmaceutical is leading manufacturer and distributer of the Lithium Carbonate among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Lithium Carbonate API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Lithium Carbonate in the domestic level as well as the international market.

Niksan Pharmaceutical provides Lithium CarbonateAPI in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Lithium Carbonate API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Lithium Carbonate is a medication used to treat manic episodes of bipolar disorder.

SYNONYMS: Dilithium Carbonate, Lithii Carbonas, Lithium Carbonate, Lithonate

IUPAC NAME: dilithium(1+) carbonate

CAS NO: 554-13-2

FORMULA: Li₂CO₃

MOLECULAR MASS: 73.891g/mol

STORAGE OF LITHIUM CARBONATE:Conditions for Safe Storage, Including Any Incompatibilities:Store in a cool, dry area. Store material tightly sealed in properly labeled containers. Do not store together with acids. See section 10 for more information on incompatible materials.

APPLICATIONS OF LITHIUM CARBONATE:Lithium carbonate is a medication usedto treat manic episodes of bipolar disorder. Lithium has been used to treat manic episodes since the 19th century³.

HOW TO USE: Take this medication by mouth as directed by your doctor, usually 2-3 times daily. Take lithium with or immediately after meals to lessen stomach upset. Do not crushor chew this medication. Doing so can release all of the drug at once, increasing the risk of side effects.

HOW LITHIUM CARBONATE WORKS:Lithium may workby changing the release of chemicals like dopamine or serotonin in your brain. Taking lithium helps you to have more control over your emotions. It helps you cope better with bipolar mood swings.

CONTRAINDICATIONS OF LITHIUM CARBONATE: Lithium should generally not be given to patients withsignificant renal or cardiovascular disease, severe debilitation or dehydration, or sodium depletion, and to patients receiving diuretics, since the risk of lithium toxicity is very high in such patients.

PHARMACOKINETICS OF LITHIUM CARBONATE:Lithium carbonate is not metabolized before excretion^Label. Lithium is primarily eliminated through the kidneys and elimination in the feces is insignificant^Label.The half life of lithium carbonate is 18 to 36 hours^Label.Other sources say it may be 7 to 20 hours⁷.

SIDE EFFECTS OF LITHIUM CARBONATE: Drowsiness, weightgain, and mildly shaking hands (fine tremor) may occur.

PRECAUTIONS: Take care in hot weather or during activities that cause you to sweat heavily such as during hot baths, saunas, or exercise. Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using lithium. Lithium may harm an unborn baby.

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is leading manufacturer and distributer of the Brivaracetam among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Brivaracetam API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Brivaracetam in the domestic level as well as the international market.

Niksan Pharmaceutical provides Brivaracetam API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Brivaracetam API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Brivaracetam is one type of medication which is used to alone and in combination with other medications to control partial onset seizures (seizures that involve only one part of the brain) in adults, children, and infants 1 month of age and older.

SYNONYMS: Brivaracetam

IUPAC NAME:(2S)-2-[(4R)-2-oxo-4-propylpyrrolidin-1-yl]butanamide

CAS NO: 357336-20-0

FORMULA: C₁₁H₂₀N₂O₂

MOLECULAR MASS: 212.15 g/mol

STORAGE OF BRIVARACETAM:The diluted solution should not be stored for more than 4 hours at room temperature and may be stored in polyvinyl chloride (PVC) bags.

APPLICATIONS OF BRIVARACETAM:Brivaracetam is used alone and in combination with other medicationsto control partial onset seizures (seizures that involve only one part of the brain) in adults, children, and infants 1 month of age and older. Brivaracetam is in a class of medications called anticonvulsants.

HOW TO USE: It isusually taken with or without food twice daily. Take brivaracetam at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Swallow the tablets whole; do not split, chew, or crush them.

HOW BRIVARACETAM WORKS:Brivaracetam is in a class of medications called anticonvulsants. It works bydecreasing abnormal electrical activity in the brain.

CONTRAINDICATIONS OF BRIVARACETAM: Brivaracetam is contraindicated inpatients who are allergic to the drug. It should also be avoided in patients with a history of kidney or liver disease, depression or suicidal thoughts, with alcohol and during pregnancy or breastfeeding.

PHARMACOKINETICS OF BRIVARACETAM: The tablets are completely absorbed and brivaracetam rapidly enters the brain. Its half-life isabout nine hourswith most of the dose being metabolised and excreted in the urine.

SIDE EFFECTS OF BRIVARACETAM: Brivaracetam may causechanges in mood or behavior, problems with coordination, or unusual tiredness or weakness. Tell your doctor right away if you start to feel depressed, anxious, angry, getting upset easily, restless, or have thoughts about hurting yourself.

PRECAUTIONS: Tell your doctor right away if you start to feel depressed, anxious, angry, getting upset easily, restless, or have thoughts about hurting yourself.

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the GLICLAZIDEfinished formulations moreover Gliclazide API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Gliclazide API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader ofGliclazide inthe domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Gliclazide to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Gliclazide formulations in many countries for many years. Niksan pharmaceutical currently exports Gliclazide API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

GLICLAZIDEis an oral antihyperglycemic agent, specifically categorized as a sulfonylurea.It is used to treat type 2 diabetes by stimulating the pancreas to release more insulin.Furthermore, gliclazide is classified as a second-generation sulfonylurea, alongside other drugs like glibenclamide and glipizide.It also falls under theBCS Class II drug categorydue to its low solubility and high permeability.

SYNONYSMS:Glimicron, Gliclazida, Diamicron

IUPAC NAME: 1-(3, 3a, 4, 5, 6, 6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea

CAS NO:21187-98-4

FORMULA:C15H21N3O3S

MOLECULAR MASS: 323.412g/mol

STORAGE CONDITIONS:Store this medication atroom temperature between 59 and 86 degrees F (15 and 30 degrees C) away from heat, light and moisture. Do not store in the bathroom. Keep this and all medications out of the reach of children. MEDICAL ALERT: Your condition can cause complications in a medical emergency.

HOW TO USE:Swallow your gliclazide tablets whole with a drink of water. Do not chew them. If you are taking 2 doses a day, take 1 dose with your breakfast and 1 dose with your evening meal. If you are taking slow-release gliclazide, take your dose once a day with breakfast.

HOW GLICLAZIDE WORKS: Gliclazide, atype 2 diabetesbystimulating the pancreas to release more insulin.It also improves the body's sensitivity to insulin, making it more effective at controlling glucose levels.Essentially, it helps the body use insulin more efficiently and effectively.

PHARMACOKINETICS OF GLICLAZIDE:Gliclazide is a sulphonylurea drug with anintermediate half-life of around 11 hours. It is extensively metabolised, and renal clearance accounts for only 4% of total drug clearance. The molecule contains an azabicyclo-octyl group which confers special properties on the basic sulphonylurea moiety.

SIDE EFFECTS OF GLICLAZIDE:Stomach ache or indigestion, Feeling sick (nausea) , Being sick (vomiting), frequent sips of water or squash to avoid dehydration, Diarrhoea, Drink lots of fluids, Constipation.

PRECAUTIONS: Tell your doctor if you are allergic to the medicine. Ask your doctors advice if you have medical history like diabetes, heart problem, liver problem, kidney disease, breast cancer or tumour. If you are taking the other medication kindly tell your doctor about it. Avoid combination with alcohol, Dont Take This Medicine During Pregnancy & Breast-Feeding.

Niksan Pharmaceutical is leading manufacturer and distributer of the Lercanidipine among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Lercanidipine API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Lercanidipine in the domestic level as well as the international market.

Niksan Pharmaceutical provides Lercanidipine API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Lercanidipine API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Lercanidipine is acalcium channel blocker medicineused to treat high blood pressure (hypertension). If you have high blood pressure, taking lercanidipine helps prevent heart disease, heart attacks and strokes.

SYNONYMS: Lercanidipine, Lercanidipino

IUPAC NAME: 3-1-[(3, 3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl 5-methyl 2, 6-dimethyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate

CAS NO: 100427-26-7

FORMULA: C₃₆H₄₁N₃O₆

MOLECULAR MASS:611.72 g/mol

STORAGE OF LERCANIDIPINE:Storebelow 30C. Protect from light and moisture. C08CA13 - lercanidipine; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.

APPLICATIONS OF LERCANIDIPINE:Lercanidipine is usedto treat high blood pressure. Your GP may also prescribe it to prevent: heart disease. heart attacks.

HOW TO USE: It's best to take lercanidipine in the morning but you can take it at any time of day. Try to make sure you take it at the same time every day.Take lercanidipine on an empty stomach, at least 15 minutes before a meal.

HOW LERCANIDIPINE WORKS:Lercanidipine is a type of medicine called a calcium channel blocker. Like other calcium channel blockers, lercanidipine works byblocking calcium going into muscles in the heart and blood vessels. Muscles need calcium to contract, so when you block the calcium, it makes the muscle cells relax and widen.

CONTRAINDICATIONS OF LERCANIDIPINE: Lercanidipine is contraindicated in patients withsevere hepatic impairment or renal impairment (GFR < 30 ml/min), including patients undergoing haemodialysis(see section 4.2 and section 4.3). Lercanidipine has been associated with the development of cloudy peritoneal effluent in patients on peritoneal dialysis.

PHARMACOKINETICS OF LERCANIDIPINE: Lercanidipine isslowly but completely absorbed from the gut. It has a total bioavailability of 10% due to an extensive first-pass effect, or up to 40% if taken after a fatty meal. Highest blood plasma levels are reached after 1.5 to 3 hours.

SIDE EFFECTS OF LERCANIDIPINE: Headaches. Make sure you rest and drink plenty of fluids, Reddening of your face, neck or chest (flushing) This usually happens when you first start taking lercanidipine, A fast, pounding or irregular heartbeat (palpitations), Swollen ankles (oedema)

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is leading manufacturer and distributer of the Melatonin among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Melatonin API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Melatonin in the domestic level as well as the international market.

Niksan Pharmaceutical provides Melatonin API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Melatonin API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Melatonin are two types:natural and synthetic (manmade). Natural melatonin is made from the pineal gland of animals. This form could be contaminated with a virus, so it's not recommended. The synthetic form of melatonin doesn't carry this risk.

SYNONYMS: Melatonin, N-Acetyl-5-methoxytryptamine

IUPAC NAME:N-[2-(5-methoxy-1H-indol-3-yl)ethyl]

CAS NO: 73-31-4

FORMULA: C₁₃H₁₆N₂O₂

MOLECULAR MASS:232.278g/mol

STORAGE OF MELATONIN:It has been found as melatonin has an acceptable stability in all storage conditions tested: Darkness at -32C, darkness at 4C, darkness at 25C, darkness at 50C, light at -32C, light at 4C, light at 25C and light at 50C until day 13, except the samples kept at room temperature in light.

APPLICATIONS OF MELATONIN:People most commonly use melatonin forinsomnia and improving sleep in different conditions, such as jet lag. It is also used for depression, chronic pain, dementia, and many other conditions, but there is no good scientific evidence to support most of these uses.

HOW TO USE: The usual starting dose isone 2mg slow release tablet taken 30 minutes to 1 hour before bedtime.

HOW MELATONIN WORKS:Melatonin isa hormone that your brain produces in response to darkness. It helps with the timing of your circadian rhythms (24-hour internal clock) and with sleep. Being exposed to light at night can block melatonin production.

CONTRAINDICATIONS OF MELATONIN: Bleeding disorders: Melatonin might make bleeding worse in people with bleeding disorders. Depression: Melatonin can make symptoms of depression worse. High blood pressure: Melatonin can raise blood pressure in people who are taking certain medications to control blood pressure. Avoid using it.

PHARMACOKINETICS OF MELATONIN: melatoninregulates the sleep-wake cycle by chemically causing drowsiness and lowering the body temperature. Melatonin is also implicated in the regulation of mood, learning and memory, immune activity, dreaming, fertility and reproduction. Melatonin is also an effective antioxidant.

SIDE EFFECTS OF MELATONIN: In some cases, Feeling sleepy or tired in the daytime. Do not drive, cycle or use tools or machinery if you're feeling this way, Headache. Make sure you rest and drink plenty of fluids, Stomach ache, Feeling sick (nausea) , Feeling dizzy, Feeling irritable or restless, Dry mouth, Dry or itchy skin.

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is worlds leading manufacturer, trader, exporter and supplier of the Fluorometholone API and Fluorometholone formulations. Niksan Pharmaceutical manufactures large quantity of Fluorometholone API and finished products in Ankleshwar, Gujarat, India. Niksan Pharmaceutical and Niksan group companies are the largest manufacturers and suppliers of Fluorometholone products.

Niksan Pharmaceutical provides best quality product of Fluorometholone in all states of India like Kerala, Punjab, Rajasthan, Telangana, Bihar, Karnataka, Jammu and Kashmir, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Delhi, Tamil Nadu, Odisha, Madhya Pradesh, Andhra Pradesh, Haryana and many other states.

Niksan Pharmaceutical exporting very big quantity of the fines quality products of Fluorometholone in all over world for many years in a countries like Puerto Rico, Taiwan, Pakistan, United States, South Korea, United Arab Emirates, Australia, Canada, Saudi Arabia, Malaysia, Thailand, Philippines, Indonesia, United Kingdom, Vietnam, Romania, Finland, Russia, Thailand, Afghanistan, Latvia, Lithuania Uzbekistan, Finland, Turkey, Pakistan, Rwanda, South Africa, Denmark, Malawi, Croatia, Malaysia, Netherland, South Africa, Slovenia, Ireland, Zambia, Cyprus, Nigeria, Paraguay, Argentina Cameroon, Arab Emirates, Seychelles, Peru, Switzerland, Tunisia, France, Hungary, , Dominican Republic, Sudan, Hong Kong, Seychelles, Algeria, Iran Netherlands, Azerbaijan, , Uruguay, Colombia Venezuela, Morocco, Cote D Ivoire, St Lucia, South Korea, Brazil, Egypt, Singapore, Jordan, Lebanon, Israel, Vietnam, Bangladesh, , United Sweden Congo, Philippines, Hungary, Mauritius, Vanuatu, Malta, Kazakistan, Slovenia, Bolivia, Japan, Uganda, Australia and many more countries.

Fluorometholone belongs to the corticosteroid class of medicine. Fluorometholone use in the treatment of certain eye conditions like redness of eye, itching of eye, or swelling of eye.

Fluorometholone normally comes in the form of eye drops.

SYNONYMS: Fluorometholon, Fluoromtholone, Fluorometholone, Fluorometholonum,

Fluorometolona

IUPAC NAME: (1R, 2S, 8S, 10S, 11S, 14R, 15S, 17S)-14-acetyl-1-fluoro-14, 17-dihydroxy-2, 8, 15-trimethyltetracyclo heptadeca-3, 6-dien-5-one

CAS NO: 426-13-1

FORMULA: C₂₂H₂₉FO₄

MOLECULAR MASS:376.46g/mol

STORAGE CONDITIONS: Store in cool and dry place. Keep away from direct heat and sun light. Do not touch the tip of the container. Do not store in bathroom or humid place.

HOW TO USE: To apply the eye drops wash your hand and eye first. Shake the bottle well before using. Do not touch the tip of the container. If you are wearing the eye lances remove your eye lance before using the medication.

HOW FLUOROMETHOLONE WORKS: Fluorometholone works by relieving the eye symptoms like eye redness, swelling, itching, irritation by inhibiting the inflammatory response.

PHARMACOKINETICS: Fluorometholone absorbed in the aqueous hour after the ophthalmic administration. After that Fluorometholone metabolizes in the kidney. The half-life of the Fluorometholone is between 7-13 hours. Fluorometholone eliminated through kidney and by feces.

SIDE EFFECTS: Blurred vision may occur whenever you apply the medication. Burning anditching also seen for 2-3 minutes after applying the medicine. Tell your doctor if problem like eye pain, high pressure inside eye, vision problem seen in the patient. By using this type of medicine the risk of eye infection, blurred vision, or eye pain also increase.

PRECAUTION: Tell your doctor if you have allergic reaction from the Fluorometholone.

The medication cause blurred vision and irritation in eye so kindly do not operate any vehicle or machineries after applying the medication. Tell your doctor if you had any eye surgery.

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

Niksan Pharmaceutical is one of the leading manufacturer, supplier and exporter of the Ondansetron. The best product manufactured by Niksan Pharmaceutical is Ondansetron. We manufacture, supply and export best quality product of OndansetronAPI along with Ondansetronformulations.

Niksan Pharmaceutical is the largest manufacturer, trader and supply of Ondansetron in all-over Ankleshwar, Gujarat, India.

Niksan Pharmaceutical manufacture and supply the Ondansetron product to the Indian states like Maharashtra, Goa, Sikkim, Madhya Pradesh, Uttar Pradesh, Assam, Haryana, Delhi, Bihar, Meghalaya, Tamilnadu, Kerala, Gujarat, Rajasthan, Rajasthan, Punjab, Karnataka, and other states.

Niksan Pharmaceutical is manufacturer , supplier and exporter of Ondansetron in many countries from many years like New Zealand, United States, Paraguay, Indonesia, Mexico, Australia, Chile, Nepal, Venezuela, Ecuador, Puerto Rico, Colombia, Uruguay, Kenya, Bolivia, Canada, Peru, Bangladesh, Portugal, Ireland, United Kingdom, Iraq, United Arab Emirates, Singapore, Sweden, Iran, Pakistan, Spain, Argentina, Philippines, Saudi Arabia, Finland, Denmark, Switzerland, Netherlands, Germany, South Africa, Thailand, Egypt, Austria, Malaysia, Italy, Belgium, France, Poland, Vietnam, Turkey, Brazil and many more countries.

Ondansetron belongs to 5-HT3 antagonist class of medicine. Ondansetron used as an anti-emetic agent to prevent nausea and vomiting caused by the cancer therapy. It is also used to prevent vomiting caused by motion sickness.

IUPAC NAME: 9-methyl-3-[(2-methyl-1H-imidazol-1-yl) methyl]-2, 3, 4, 9-tetrahydro-1H-carbazol-4-one

CAS NO: 99614-02-5

FORMULA: C₁₈H₁₉N₃O

MOLECULAR MASS:293.4g/mol

STORAGE CONDITIONS: Store in cool and dry place, away from heat and light. Do not put in bathroom or ant misty place. Keep away from children.

HOW TO USE: This medication come in mouth dissolving formulation, so do not chew or break the medicine. Place medicine on the tip of the tongue and allow dissolving it. Swallow the medicine after dissolves in the mouth.

HOW ONDANSETRON WORKS: Ondansetron used as anti-emetic agent. Ondansetron blocks the action of 5-HT3 receptor which causes the nausea and vomiting symptoms.

PHARMACOKINETICS: Ondansetron absorbed in GI after the oral administration. Almost 73% drug binds with the plasma protein. The half life of Ondansetron is 3-4 hours. Ondansetron eliminated from body by urination and feces.

SIDE EFFECTS: Side effects cause by Ondansetron is dizziness, light headedness, drowsiness, headache, tiredness. Other side effects like chest pain, irregular heartbeats, fainting, and abdominal pain. Muscle pain seen in the patients.

PRECAUTIONS: Before taking the medication tell your doctor if you are allergic towards the medicine. The medicine makes you dizzy so kindly avoid drinking alcohol and cannabis. This drug makes you dizzy so kindly avoid driving or operating machineries.

CDSCO APPROVAL: R-Ondansetron (As HCl. Dihydrate) (1mg/ml) injection approved by CDSCO in India in 12.01.2007,

Ondansetron Fast Dissolving Strips 4mg/8mg (New dosage form) approved by CDSCO in India in22.11.2011

Ondansetron orally disintegrating tablet (4mg/8mg) (additional dosage form)approved by CDSCO in India in 10.10.2007

Ondansetron tablet and injection approved by CDSCO in India in12.02.1994

Ondansetron Rapid Film Oral Strip 4/8 mg approved by CDSCO in India in16.11.2010

Ondansetron Hydrochloride Mouth Melting Strips 4mg approved by CDSCO in India in29.03.2012

R (+) Ondansetron (2mg/4mg) tablet approved by CDSCO in India in15.04.2005

Ondansetron Hydrochloride Oral Spray 2mg (Each spray delivers ondansetron-2mg)approved by CDSCO in India in 08.11.2012

R (-) Ondansetron oral Solution (1mg/5ml) approved by CDSCO in India in27.05.2005

Niksan Pharmaceutical is leading manufacturer and distributer of the Lacosamide among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Lacosamide API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Lacosamide in the domestic level as well as the international market.

Niksan Pharmaceutical provides Lacosamide API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Lacosamide API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Lacosamide is one type ofanticonvulsants medication.It works by decreasing abnormal electrical activity in the brain.

SYNONYMS: Erlosamide, Harkoseride, Lacosamida, Lacosamide

IUPAC NAME: (2R)-N-benzyl-2-acetamido-3-methoxypropanamide

CAS NO: 175481-36-4

FORMULA: C₁₃H₁₈N₂O₃

MOLECULAR MASS:250.2936 g/mol

STORAGE OF LACOSAMIDE:stored in glass or polyvinyl chloride (PVC) bags at ambient room temperature 15-30C (59-86F). Keep them away from light and moisture.Keep all medicines out of reach of children. The oral solution should be used within 7 weeks of opening the bottle.

APPLICATIONS OF LACOSAMIDE:Lacosamide is usedto control partial onset seizures(seizures that involve only one part of the brain) in adults and children 1 month of age and older.

HOW TO USE: Lacosamide comes as a tablet and as an solution (liquid) to take by mouth. It isusually taken twice a day with or without food. Take lacosamide at around the sametimes every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

HOW LACOSAMIDE WORKS:Lacosamide is an antiepileptic drug approved in the USA and Europe as adjunctive therapy for partial-onset seizures. Studies suggest that lacosamideselectively enhances slow inactivation of voltage-gated sodium channels and possibly interacts with collapsin response mediator protein-2.

CONTRAINDICATIONS OF LACOSAMIDE: Lacosamide is contraindicated in patients who have demonstrated a hypersensitivity to the drug or its ingredients, Depression, suicidal ideation, Hepatic disease, Phenylketonuria, Pregnancy, Breast-feeding.

PHARMACOKINETICS OF LACOSAMIDE: The maximum Lacosamide plasma concentrations occur about 1-4 hours after oral administration, and the pharmacokinetics of Lacosamide aredose proportional. Food does not affect absorption. approximately 0.6 L/kg; thus close to the volume of total body water. Lacosamide is a CYP2C19 substrate.

SIDE EFFECTS OF LACOSAMIDE Common lacosamide (Vimpat) side effects include dizziness, headache, and nausea. Fatigue and vision changes are also possible. These side effects are more likely with higher doses of lacosamide andusually go away over time.

PRECAUTIONS: you should know that lacosamide may make you dizzy or drowsy and may cause blurred vision or problems with coordination and balance.Do not drive a car, operate machinery, or participate in activities requiring alertness or coordination until you know how this medication affects you.

Niksan Pharmaceutical is the largest manufacturer and exporter of the Cilostazol among all over the world. Niksan Pharmaceutical is one of biggest the supplier, manufacturer, exporter and distributer of the Cilostazol API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical provides API and finished formulations of Cilostazol in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu Kashmir Etc.

Niksan pharmaceutical is also large exporter of the API and finished pharmaceutical products of Cilostazol in many countries for years. The countries where we exporting are Puerto Rico, Brazil, Honduras, Argentina, Nicaragua, Philippines, Colombia, Guatemala, Uruguay, Mexico, Chile, Dominican Republic, Panama, South Korea, United States, El Salvador, Venezuela, Taiwan, Indonesia, Bolivia, Peru, Ecuador, Romania, Hong Kong, Thailand, United Arab Emirates, Iraq, Serbia, Spain, Bulgaria, Greece, Pakistan, Hungary, Portugal, Vietnam, Egypt, Iran, Poland, Czechia, Germany, Malaysia, Saudi Arabia, Canada, United Kingdom, Australia, Japan, Turkey, Italy and many more countries.

Cilostazol is belongs to drugs class called platelet-aggregation inhibitors. It is works by improving blood flow in legs. Cilostazol is anti-platelet type of drug and it also used as vasodilator.

Cilostazol stops blood cells to combine or stick together and inhibits blood clots. Cilostazol is used to increase the blood flow because of that the Oxygen flow in body also increases. Cilostazol is one type of vasodilators so it is also helps blood to flow smoothly in body.

SYNONYMS: Cilostazol, Cilostazole, Cilostazolum

IUPAC NAME: 6-[4-(1-cyclohexyl-1H-1, 2, 3, 4-tetrazol-5-yl) butoxy]-1, 2, 3, 4-tetrahydroquinolin-2-one

CAS NO: 73963-72-1

FORMULA: C₂₀H₂₇N₅O₂

MOLECULR MASS: 369.46g/mol

STORAGE: Store it in cool and dry place, away from moisture and direct light. Does not store this medicine in bathroom or any humidly place. Keep medicine away from the reach of children and pets.

APPLICATIONS: Cilostazol is widely used as vasodilator. Cilostazol is also use in the treatment ofintermittent claudication. Cilostazol also use to treat cramp, ache, fatigue, classically it is used in calf muscle during the workout.

HOW TO USE: Follow all directions on your prescription label or as your doctor recommends you. Take Cilostazol two times per day on an empty stomach. Take medicine at least 45 minutes or 2 hours before meal. Cilostazol takes time like 8-12 weeks to improve your symptoms. But if your symptoms do not improve after 3-4 weeks treatments tell you doctor. Try to take medicine at a same time each day to improve effectiveness.

HOW CILOSTAZOL WORKS: Cilostazol and Cilostazol metabolites are one type of posphodiesterase III inhibitors (PDA III inhibitors). Cilostazol inhibits activity of posphodiesterase and also quash cAMP degradation so by that cAMP increased in Blood vessels and platelets and by this activity the platelet degradation inhibits and also blood clotting reduced by the activity.

SIDE EFFECTS OF CILOSTAZOL: The common side effects of Cilostazol are headache, upset bowel movements, runny nose, normal rash, dizziness. There are some major side effects are also cause by the Cilostazol like difficulty in breathing, chest pain, swelling of (face, tongue, fingers, and throat). Take your doctors instructions at the minute if you have symptoms like Fever, chills, body aches, flu symptoms. Paining while urinating or bloody urine Shortness of breath, swelling of feet and fingersChest pain, irregular heartbeats.

Niksan Pharmaceutical is leading manufacturer and distributer of the Lornoxicam among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Lornoxicam API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Lornoxicam in the domestic level as well as the international market.

Niksan Pharmaceutical provides Lornoxicam API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Lornoxicam API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Lornoxicam (chlortenoxicam)is a newnonsteroidal anti-inflammatory drug (NSAID) of the oxicam classwith analgesic, anti-inflammatory and antipyretic properties.

SYNONYMS: Chlortenoxicam, Lornoxicam, Lornoxicamum

IUPAC NAME: 6-chloro-4-hydroxy-2-methyl-1, 1-dioxo-N-(pyridin-2-yl)-2H-1-thieno[2, 3-e][1, 2]thiazine-3-carboxamide

CAS NO: 70374-39-9

FORMULA: C₁₃H₁₀ClN₃O₄S₂

MOLECULAR MASS:371.81 g/mol

STORAGE OF LORNOXICAM:No special storage conditions are required.

APPLICATIONS OF LORNOXICAM:LORNOXICAM is usedto reduce and relieve pain and inflammation (swelling) in osteoarthritis and rheumatoid arthritis. LORNOXICAM works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins.

HOW TO USE: It should be taken with food or milk to avoid getting an upset stomach. It can cause serious complications like stomach bleeding and kidney problems if taken for a long time. Lornoxicam can raise your risk of blood clots, heart attack, or a stroke.

HOW LORNOXICAM WORKS:LORNOXICAM is used to reduce and relieve pain and inflammation (swelling) in osteoarthritis and rheumatoid arthritis. LORNOXICAM works byblocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins.

CONTRAINDICATIONS OF LORNOXICAM: The drug is contraindicated in patients who must not take other NSAIDs, possible reasons including salicylate sensitivity, gastrointestinal bleeding and bleeding disorders, and severe impairment of heart, liver or kidney function.

PHARMACOKINETICS OF LORNOXICAM: Lornoxicam is eliminated following biotransformation to 5'-hydroxy-lornoxicam, which does not undergo enterohepatic recirculation.Glucoroconjugated metabolites are excreted in urine and faeces with a half-life of about 11 hours. Lornoxicam and its metabolites bind extensively to plasma albumin.

SIDE EFFECTS OF LORNOXICAM: Allergic reaction like fever, chills, rash, hives, breathing difficulty, swelling over your face, lips, throat, running/stuffy nose and sneezing, Swelling (inflammation) of the intestine, Diarrhea, nausea, vomiting and indigestion, Blood disorders, Vision trouble, sensitivity to light.

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Niksan Pharmaceutical is leading manufacturer and distributer of the Closantel Sodium among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Closantel Sodium API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Closantel Sodium in the domestic level as well as the international market.

Niksan Pharmaceutical provides Closantel Sodium API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Closantel Sodium API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Closantel Sodium is one type of synthetic anti parasitic agentwhich is highly effective against adults and larvae (6 to weeks old) of liver flukes (Fasciola hepatica), and against several important gastrointestinal roundworms.

SYNONYMS: Closantel sodium, Closantel(sodium)

IUPAC NAME: sodium;2-[[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]carbamoyl]-4, 6-diiodophenolate

CAS NO: 61438-64-0

FORMULA: CHClINNaO

MOLECULAR MASS: 685.1 g/mol

STORAGE OF CLOSANTEL SODIUM:Store at room temperature.

APPLICATIONS OF CLOSANTEL SODIUM: Closantel is asynthetic anti parasitic agentwhich is highly effective against adults and larvae (6 to weeks old) of liver flukes (Fasciola hepatica), and against several important gastrointestinal roundworms (e.g. Bunostomum, Haemonchus, Oesophagostomum, Ostertagia - Teladorsagia, Strongyloides, Trichostrongylus).

HOW TO USE: 5.25 g of closantel sodium, 1 g of hydroxypropyl cyclodextrin and 0.5 g of povidone are dissolved in each 100 mL of the mixed solvent.

HOW CLOSANTEL SODIUM WORKS:causes an initial burst of contractions of much greater amplitude and frequency than normal in tissue vessel, the stimulation of amplitude and frequency lasted for nearly 15 min and is accompanied by a rise in muscle tone, which reaches a maximum at 16 min, at a level greater than 1.5 times.

CONTRAINDICATIONS OF CLOSANTEL SODIUM: It is widely used in management of parasitic infestation in animals but iscontraindicated in humans and in high dose in milk producing animalsbecause of its secretion in milk.

PHARMACOKINETICS OF CLOSANTEL SODIUM: Rapidly absorbed into the systemic circulation with peak plasma levels at 24-48 hours after dosing. In plasma, closantel is bound 99% to albumin.

SIDE EFFECTS OF CLOSANTEL SODIUM Its inhibition interrupts their development to adult worms. This drug possesses some side effects:hyper acute anaphylactic reactions in cattle; hypersensitivity reactions; overdoses can cause reduced visibility or blindness, anorexia, lack of coordination and general weakness.

PRECAUTIONS:

P202 Do not handle until all safety precautions have been read and understood.

P260Do not breathe mist or vapors. P264 Wash skin thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

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Niksan Pharmaceutical is among worlds top most manufacturer, supplier, exporter and trader of the Adapalene finished formulations moreover Adapalene API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Adapalene API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical provides API and finished formulations of Adapalene in all over Indian states Like Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, Jammu Kashmir Etc.

Niksan pharmaceutical is also large exporter of the API and finished pharmaceutical products of Adapalene in many countries for years. The countries where we exporting are Nepal, Sri Lanka, Malaysia, Philippines, Kenya, Singapore, Hong Kong, Pakistan, United Arab Emirates, United States, Puerto Rico, Argentina, Egypt, Qatar, Taiwan, Algeria, Jordan, Uruguay, United Kingdom, Canada, Bangladesh, New Zealand, Saudi Arabia, Australia, Colombia, France, Vietnam, Ireland, Iraq, Thailand, South Africa, Ecuador, Serbia, Peru, Indonesia, Morocco, Israel, Greece, Romania, Mexico, Iran, Switzerland, Norway, Italy, Denmark, Belgium, South Korea, Netherlands, Venezuela, Hungary, Chile, Sweden, Germany, Ukraine, Spain, Poland, Brazil, Turkey, Russia, Japan and many more countries.

Adapalene is one kind of skin care product. Adapalene belongs to the retinoid like compound. Adapalene used in skin care and works by stopping the pimples from forming under the skin.

SYNONYMS: Adapalene, Adapalnem, Adapaleno, Adapalenum

IUPAC NAME: 6-[3-(adamantan-1-yl)-4-methoxyphenyl] naphthalene-2-carboxylic acid

CAS NO: 106685-40-9

FORMULA: C₂₈H₂₈O₃

MOLECULAR MASS: 412.52g/mol

STORAGE CONDITIONS: Store in cool and dry place, away from direct heat and light.

Do not place in bathroom or kitchen. Keep away from the children and pet.

HOW TO USE: Use this medication on your skin. Wash clean and dry your skin before using the medication. Wash your hands before using the gel, tube or lotion. Do not apply medicine on eyes.

HOW ADAPALENE WORKS: Adapalene works by inhibiting the acne formulation under the skin. Adapalene binds with the retinoid receptor and activates it. Adapalene also use in the beauty care products.

PHARMACOKINETICS: Adapalene absorbed through skin after topical application, used only 2g of 0.3% gel. The half-life of Adapalene 0.3% gel id between 7-51 hours. Almost 25% of drug metabolised in the body. 75% of drug remains unchanged and eliminated by the biliary route.

SIDE EFFECTS: The stinging like sensation occurs after applying the medicine. Side effects like burning, irritation, swelling of skin, itching, dryness of skin, burning are seen in the first 5-6 days of using the medicine. If you see side effects like irritation, intense burning, redness of eye, skin discolouration contact your doctor.

PRECAUTIONS: Before using the medication tell your doctor if you are allergic to Adapalene. Tell your doctor if you have any problem like skin problem, eczema etc. Do not apply this medicine on open wounds. Do not apply on eye or burned part of skin.

CDSCO APPROVAL: Adapalene 0.1% w/w approved by CDSCO in India in 15.03.2001,

Adapalene 0.1% + Benzoyl Peroxide 2.5% gel approved by CDSCO in India in 31.10.2008,

Adapalene + clindamycin gel approved by CDSCO in India in 01.05.2003

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Niksan Pharmaceutical is leading manufacturer and distributer of the Alpha Lipoic Acid 80% Coated among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Alpha Lipoic Acid 80% Coated API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Alpha Lipoic Acid 80% Coated in the domestic level as well as the international market.

Niksan Pharmaceutical provides Alpha Lipoic Acid 80% Coated API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Alpha Lipoic Acid 80% Coated API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Alpha Lipoic Acid 80% Coated is one type of biological antioxidantthat is proven to quench hydroxyl radicals, hypochlorous acid and singlet oxygen, increases the levels of CoQ (ubiquinone) which recycles vitamin E, and regenerates glutathione.

SYNONYMS: -Lipoic acid, Alpha lipoic acid, Thioctic acid, 6, 8-Dithiooctanoic acid

IUPAC NAME: (R)-5-(1, 2-dithiolan-3-yl)pentanoic acid

CAS NO: 1077-28-7

FORMULA: C₈H₁₄O₂S₂

MOLECULAR MASS: 206.33g/mol

STORAGE OF ALPHA LIPOIC ACID 80% COATED:Recommended storage temperature:2 - 8 CKeep in a dry place.

APPLICATIONS OF ALPHA LIPOIC ACID 80% COATED:Alpha Lipoic Acid is a biological antioxidant that is proven toquench hydroxyl radicals, hypochlorous acid and singlet oxygen, increases the levels of CoQ (ubiquinone) which recycles vitamin E, and regenerates glutathione.

HOW TO USE: Alpha-lipoic supplements arebest taken on an empty stomach, as certain foods can lower the acid's bioavailability (40). Though there is no set dosage, most evidence suggests that 300600 mg is sufficient and safe. Alternatively, you can follow the instructions on the back of the bottle.

HOW ALPHA LIPOIC ACID 80% COATED WORKS:Alpha-lipoic acid is an antioxidant made by the body. It is found in every cell, where ithelps turn glucose into energy. Antioxidants attack "free radicals, " waste products created when the body turns food into energy.

PHARMACOKINETICS OF ALPHA LIPOIC ACID 80% COATED: Alpha lipoic acid (ALA) is an antioxidant. It isquickly absorbed from the gastrointestinal tract. It dissolves in both water and fat in the body. ALA is rapidly absorbed after oral ingestion of 50 to 600 mg thioctic acid. The time required to reach the maximum plasma concentrations was about0.5 to 1 h.

SIDE EFFECTS OF ALPHA LIPOIC ACID 80% COATED: The most common side effects areheadache, heartburn, nausea, and vomiting. When applied to the skin: Alpha-lipoic acid is possibly safe for most adults when used as a cream for up to 12 weeks. It might cause a rash in some people.

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Niksan Pharmaceutical is leading manufacturer and distributer of the Leflunomide among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Leflunomide API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Leflunomide in the domestic level as well as the international market.

Niksan Pharmaceutical provides Leflunomide API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Leflunomide API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Leflunomide is in a class of medications calleddisease-modifying antirheumatic drugs (DMARDs). It works by decreasing inflammation and slowing the progress of the condition, which can help improve the physical activity of people with rheumatoid arthritis.

SYNONYMS: Leflunomida, Leflunomide, Lflunomide, Leflunomidum

IUPAC NAME: 5-methyl-N-[4-(trifluoromethyl)phenyl]-1, 2-oxazole-4-carboxamide

CAS NO: 75706-12-6

FORMULA: C₁₂H₉F₃N₂O₂

MOLECULAR MASS:270.2073 g/mol

STORAGE OF LEFLUNOMIDE:Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

APPLICATIONS OF LEFLUNOMIDE:Leflunomide is a medication used in themanagement and treatment of rheumatoid arthritis. It is in the non-biologicalDMARDsclass of medications.

HOW TO USE: Leflunomideusually is given as a 20 mg tablet once a day. Sometimes, patients are given 10 mg, especially if they experienced side effects with the higher dose. Leflunomide should be taken with food. Complete benefits may not be experienced until 612 weeks after starting the medication.

HOW LEFLUNOMIDE WORKS:Leflunomide is used to relieve symptoms caused by active rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain. This medicine works bystopping the body from producing too many of the immune cells that are responsible for the swelling and inflammation.

CONTRAINDICATIONS OF LEFLUNOMIDE: Leflunomide is contraindicated insevere hepatic impairment due to hepatotoxicity. Other contraindications include hypersensitivity, previous or current skin reactions, immunosuppression, and impaired bone marrow function.

PHARMACOKINETICS OF LEFLUNOMIDE: Approximately 90% of a single dose of leflunomide is eliminated, 43% in urine, primarily as leflunomide glucuronides and an oxalinic acid derivative. Leflunomide is a prodrug that israpidly and almost completely metabolized following oral administrationto its pharmacologically active metabolite.

SIDE EFFECTS OF LEFLUNOMIDE: In some cases, Bloody or cloudy urine, cough, difficult or painful, breathing, difficult, burning, or painful urination, dizziness, fever, frequent urge to urinate, headache.

PRECAUTIONS: Blood or bone marrow problems, history of or-Bone marrow dysplasia or.Immune systemproblem or.Infection, severe or uncontrolled or.Tuberculosis, history of or.Weak immune systemUse is not recommended in patients with these conditions.

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Niksan Pharmaceutical is leading manufacturer and distributer of the Desloratadine among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Desloratadine API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Desloratadine in the domestic level as well as the international market.

Niksan Pharmaceutical provides Desloratadine API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Desloratadine API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Desloratadine is one type of antihistamine. It is used to relieve the symptoms of hay fever and hives of the skin. Antihistamines work by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.

SYNONYMS: Descarboethoxyloratadine, Desloratadina, Desloratadine

IUPAC NAME: 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^3, 8]pentadeca-1(11), 3(8), 4, 6, 12, 14-hexaene

CAS NO: 100643-71-8

FORMULA: C₁₉H₁₉ClN₂

MOLECULAR MASS: 310.82 g/mol

STORAGE OF DESLORATADINE:

Blisters: This medicinal productdoes not require any special storage conditions.

Bottles: This medicinal product does not require any special temperature storage conditions.

APPLICATIONS OF DESLORATADINE: Desloratadine is used in adults and childrento relieve hay fever and allergy symptoms, including sneezing; runny nose; and red, itchy, tearing eyes. It is also used to relieve symptoms of urticaria (hives; red, itchy raised areas of the skin), including itching and rash.

HOW TO USE: Desloratadine comes as a tablet, oral solution (liquid), and an orally disintegrating tablet to take by mouth. It isusually taken once a day with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

HOW DESLORATADINE WORKS:Desloratadine is an antihistamine. It is used to relieve the symptoms of hay fever and hives of the skin. Antihistamines workby preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.

CONTRAINDICATIONS OF DESLORATADINE: Desloratadine products are contraindicated inpatients who are hypersensitive to Desloratadine or to any of the product ingredients or to loratadine. The anticholinergic activity of H1-antagonists may result in thickened bronchial secretions in the respiratory tract thereby aggravating asthma or an asthmatic attack.

PHARMACOKINETICS OF DESLORATADINE: Desloratadine iswell absorbed from the gut and reaches highest blood plasma concentrations after about three hours. In the bloodstream, 83 to 87% of the substance are bound to plasma proteins. Desloratadine is metabolized to 3-hydroxydesloratadine in a three-step sequence in normal metabolizers.

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Niksan Pharmaceutical is top leading manufacturer, supplier, exporter and trader in Indian states and also in world other countries. Orlistat is the best product of Niksan Pharmaceutical which exporting as a form of API and finished formulation.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader in the domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supply and manufacture the Orlistat to all Indian states like Andhra Pradesh, Jammu & Kashmir, Punjab, Delhi, Maharashtra, Karnataka, Chandigarh, Gujarat, Tamil Nadu, Haryana, West Bengal, Telangana, Kerala, Uttar Pradesh, Rajasthan, Madhya Pradesh, Bihar and many other states of India.

Niksan pharmaceutical and Niksan group companies are exporter, supplier and manufacturer of the API and also Orlistat formulations in many countries for many years. Niksan pharmaceutical currently exports Orlistat API and Formulation to countries like Mexico, Brazil, Colombia, Chile, Venezuela, Dominican Republic, Ecuador, Paraguay, Lebanon, United Kingdom, Bolivia, Argentina, Panama, Peru, Uruguay, Philippines, Pakistan, Guatemala, Costa Rica, Iraq, Spain, Germany, Belgium, Malaysia, Czechia, United Arab Emirates, Egypt, Nigeria, Bangladesh, Switzerland, Italy, Denmark, Vietnam, Ireland, United States, Portugal, Austria, Singapore, Australia, Finland, Saudi Arabia, Canada, Poland, South Africa, Indonesia, Sweden, Netherlands, Romania, Taiwan, France, Turkey, Thailand, Iran, Japan and many other countries.

Orlistat is used to treatment of obesity.

SYNONYMS: Orlipastat, Orlipastatum, Orlistat, Tetrahydrolipstatin

IUPAC NAME: (2S)-1-[(2S, 3S)-3-hexyl-4-oxooxetan-2-yl] tridecan-2-yl (2S)-2-formamido-4-methylpentanoate

CAS NO: 96829-58-2

FORMULA: C₂₉H₅₃NO₅

MOLECULAR MASS: 495.73 g/mol

STORAGE OF Orlistat: Store it in cool and dry place, away from moisture and direct light. Keep away from children or pets. Do not store this medicine in bathroom and kitchen or any humidly place.

APPLICATIONS OF Orlistat: Orlistat is used to control your diet plan and help you in lose weight. Orlistat is also used to treatment of behaviour changes and reduce-calorie.

HOW TO USE: Orlistat is distributed as a capsule form so you can take it by mouth with or without food. Take Orlistat before meal or 1 hour after meal.

HOW OrlistatWORKS: Orlistat breaks down fat in your diet by blocking enzymes.

CONTRAINDICATIONS: Kindly avoid this tablet if you have anorexia nervosa, Bulimia or liver tissue death. If you are patent of liver damage or liver failure kindly avoid Orlistat medication. Do not take Orlistat if you have high amount of oxalic acid in your urine. If you have low thyroid hormone level in your body kindly avoid Orlistat drug. Do not take Orlistat during pregnancy. If you have allergic to Orlistat tell your doctor before taking medication.

PHARMACOKINETICS OF Orlistat: Systemic absorption of Orlistat is minimal after the administration. Half life is approximately 1 to 2 hour after administration. 99% Orlistat drug bound to plasma proteins. Time of peak plasma concentration is 8 hour and peak plasma concentration is less than 5 mg/ml. Orlistat largely eliminated by feces.

SIDE EFFECTS OF Orlistat: Most common side effects of Orlistat are loose stools

Clay-collared stools, Diarrhea, Rectal pain, Nausea, Vomiting and Stomach pain. Weaknesses, Dark urine, Itching, Loss of appetite, yellowing of the skin or eyes are other side effects of Orlistat. In the rare case patient may see Headache, Back pain, Skin rash and cough.

FORMULATIONS AVAILABLE IN MARKET:

Orlistat 60 MG capsules

Orlistat 120 MG capsules

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Niksan Pharmaceutical is leading manufacturer and distributer of the Deflazacort among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Deflazacort API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Deflazacort in the domestic level as well as the international market.

Niksan Pharmaceutical provides Deflazacort API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Deflazacort API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Deflazacort is one type of medication which is used to reducing inflammation (swelling) and by changing the way the immune system works.

SYNONYMS: Deflazacort

IUPAC NAME: [2-[(1S, 2S, 4R, 8S, 9S, 11S, 12S, 13R)-11-hydroxy-6, 9, 13-trimethyl-16-oxo-5-oxa-7-azapentacyclo[10.8.0.02, 9.04, 8.013, 18]icosa-6, 14, 17-trien-8-yl]-2-oxoethyl] acetate

CAS NO: 14484-47-0

FORMULA: C₂₅H₃₁NO₆

MOLECULAR MASS:441.517g/mol

STORAGE OF DEFLAZACORT:Store it atroom temperature (25C).

APPLICATIONS OF DEFLAZACORT: Deflazacort is usedto treat Duchenne muscular dystrophy(DMD; a progressive disease in which the muscles do not function properly) in adults and children 2 years of age and older. Deflazacort is in a class of medications called corticosteroids.

HOW TO USE: Deflazacort comes as a tablet and a suspension (liquid) to take by mouth. It isusually taken once a day with or without food. Take deflazacort at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

HOW DEFLAZACORT WORKS:It worksby reducing inflammation (swelling) and by changing the way the immune system works.

CONTRAINDICATIONS OF DEFLAZACORT: If you are allergic to deflazacort or similar medicines.

If you have an infection and you are not taking any anti-infective medicine. If you are having or recently had any vaccination with a live vaccine. Taking deflazacort during early pregnancy may increase the risk of cleft lip and palate in a newborn.

PHARMACOKINETICS OF DEFLAZACORT: Deflazacort is a corticosteroid prodrug with an active metabolite, 21-deflazacort, whichbinds to the glucocorticoid receptor to exert anti-inflammatory and immunosuppressive effects on the body.

SIDE EFFECTS OF DEFLAZACORT: headache, thin, fragile skin, red or purple blotches or lines under the skin, increased hair growth, acne, bulging eyes, irregular or absent menstrual periods, slowed healing of cuts and bruises.

PRECAUTIONS: This medicinemay increase your risk of developing blood clots. Check with your doctor right away if you or your child have swelling and pain in your arms, legs, or stomach, chest pain, shortness of breath, loss of sensation, confusion, or problems with muscle control or speech.

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NIiksan Pharmaceutical is the worlds leading pharmaceutical company in the field of manufacturing, supplying and exporting of Loperamide and API. Niksan pharmaceutical provides wide range of API and Finished pharmaceutical products of Loperamide to the Niksan group companies and also to our customers in very affordable price.

Niksan Pharmaceutical are the manufacturer, supplier and exporter of the Loperamide in domestic and as well as worldwide.

Niksan Pharmaceutical are manufacturing and supplying Loperamide in the all over the Indians states like Punjab, Tamilnadu, Gujarat, Delhi, Uttar Pradesh, Bihar, Rajasthan, Maharashtra, west Bengal, Assam, Odisha.

Niksan Pharmaceutical manufacture and exports large quantity of Loperamide among the other nations from many years like Zimbabwe, Philippines, Tanzania, Singapore, Cambodia, Nepal, Ghana, Latvia, New Zealand, Kenya, Nigeria, South Africa, Netherlands, Puerto Rico, Indonesia, United Kingdom, France, United States, Canada, Moldova, Vietnam, Malaysia, Iraq, Sri Lanka, United Arab Emirates , Hong Kong, Jordan, Belgium, Australia, Ireland, Italy, Algeria, Pakistan, Thailand, Bangladesh, Taiwan, Saudi Arabia, Morocco, Israel , South Korea, Switzerland, Egypt, Iran, Romania , Sweden, Peru, Greece, Mexico, Spain , Colombia, Germany, Turkey, Poland, Japan, Brazil and many other countries.

Loperamide comes in the medicine class called antidiarrheal agents. Loperamide used in the treatment of diarrhoea and also use to control the frequency of diarrhoea. Loperamide is also used in the inflammatory bowel disease and short bowl syndromes.

SYNONYMS: Loperamid, Loperamida, Lopramide, Loperamide, Loperamidum.

IUPAC NAME: 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-N, N-dimethyl-2, 2-diphenylbutanamide

CAS NO: 53179-11-6

FORMULA: C₂₉H₃₃ClN₂O₂

MOLECULAR MASS: 477.04 g/mol (513.51 with HCl)gmol

STORAGE CONDITION: Store medication at room temperature in dry place. Put it away from light and excessive heat. Do not put medication in bathroom or in kitchen. Keep it away from the range of children and pet.

HOW TO USE LOPERAMIDE: Take the medicine by mouth after the each loose stool. The dosage form might be different in children and adult. Do not take more than 8 mg dose in 24 hours. If you are taking the chewing tablet of Loperamide take it in empty stomach. Ask for your doctors advice if needed.

HOW LOPERAMIDE WORKS: Loperamide decrease the flow of liquid and electrolyte to the bowel, by doing this the bowel movement becomes slow by this the bowel movement will be decrease.

PHARMACOKINETIKCS OF LOPERAMIDE: Loperamide plasma concentrations will reach highest in 5hrs after taking the capsules and administration of liquid make it fast in approx. 2.5 hrs. The half-life of Loperamide is average 9.5-11.5 hrs. Loperamide binds with approximately 97% of plasma. The excretion of Loperamide is mostly done by feces.

SIDE EFFECTS OF LOPERAMIDE: The common side effects like dizziness, drowsiness, weakness. If taken in more quantity it can cause constipation also. Stop taking medicine if you see some side effects like nausea, vomiting, stomach pain, constipation, fast irregular heartbeats. The allergic reaction of this drug is rare but if you find effects like rash/itching, irritation tell your doctor about it.

PRECAUTIONS OF LOPERAMIDE: If you are taking the rapidly dissolving tablets keep your hand dry before taking medicine out of packet. Place tablet in mouth wait for it to dissolve and the swallow it with saliva. Stop taking medicine if you see some side effects like nausea, vomiting, stomach pain, constipation, fast irregular heartbeats. Tell your doctor if you have any allergic reaction with Loperamide.

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Niksan Pharmaceutical is one of the biggest manufacturer, supplier, exporter and trader of the SEVELAMER CARBONATE finished formulations moreover SEVELAMER CARBONATE API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of SEVELAMER CARBONATE API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical is the suppliers, manufacturer, exporters and trader ofSEVELAMER CARBONATE in the domestic level as well as the international market.

Niksan Pharmaceutical is an Indian based pharmaceutical company so it also supplies and manufactures the SEVELAMER CARBONATE to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu & Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also SEVELAMER CARBONATE formulations in many countries for many years. Niksan pharmaceutical currently exports SEVELAMER CARBONATE API and Formulation to countries like New Zealand, Jordan, Belgium, United Kingdom, Australia, Italy, Ireland, Hong Kong, Morocco, , Portugal, France, South Africa, Philippines, Malaysia, Singapore, Israel, Greece, Saudi Arabia, Egypt, Taiwan, Netherlands, South Korea, Switzerland, Algeria, Pakistan, Canada, Vietnam, United States, Germany, Brazil and many other countries.

SEVELAMER CARBONATE is a phosphate binder used to treat hyperphosphatemia. Its medication used to control the levels of the nutrient, phosphate, in the blood.